U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    Ctnnb1 catenin beta 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 84353, updated on 27-Nov-2024

    Summary

    Official Symbol
    Ctnnb1provided by RGD
    Official Full Name
    catenin beta 1provided by RGD
    Primary source
    RGD:70487
    See related
    EnsemblRapid:ENSRNOG00000054172 AllianceGenome:RGD:70487
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Catnb
    Summary
    Enables several functions, including alpha-catenin binding activity; delta-catenin binding activity; and ionotropic glutamate receptor binding activity. Involved in several processes, including cellular response to insulin-like growth factor stimulus; cellular response to lithium ion; and cellular response to mechanical stimulus. Located in several cellular components, including dendritic shaft; intercalated disc; and lateral plasma membrane. Part of protein-containing complex. Used to study colon adenocarcinoma and lung carcinoma. Biomarker of Alzheimer's disease and colorectal cancer. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant intellectual developmental disorder 19; exudative vitreoretinopathy 7; hepatocellular carcinoma (multiple); reproductive organ cancer (multiple); and urinary system cancer (multiple). Orthologous to human CTNNB1 (catenin beta 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 1354.8), Lung (RPKM 1330.0) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ctnnb1 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (129517576..129544661)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (120640008..120667110)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (129601511..129628378)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134480116 Neighboring gene uncharacterized LOC102550417 Neighboring gene unc-51 like kinase 4 Neighboring gene uncharacterized LOC134480250 Neighboring gene uncharacterized LOC120094299

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables I-SMAD binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables I-SMAD binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables RNA polymerase II-specific DNA-binding transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables RNA polymerase II-specific DNA-binding transcription factor binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables SMAD binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables alpha-catenin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables alpha-catenin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables alpha-catenin binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables alpha-catenin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables cadherin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cadherin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables cadherin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables cadherin binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables cadherin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables delta-catenin binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables disordered domain specific binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables disordered domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone methyltransferase binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ionotropic glutamate receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables molecular function activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables nitric-oxide synthase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables nuclear estrogen receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nuclear estrogen receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nuclear receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nuclear receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleic acid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein phosphatase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein phosphatase binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein phosphatase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-containing complex binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables signaling receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription coactivator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables transcription coregulator binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription corepressor binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transcription corepressor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transmembrane transporter binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transmembrane transporter binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in Schwann cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within T cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in T cell differentiation in thymus IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within T cell differentiation in thymus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in acinar cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within acinar cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in adherens junction assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in adherens junction assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in adherens junction assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within adherens junction organization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within animal organ development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in anterior/posterior axis specification IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within anterior/posterior axis specification ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in apoptotic signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in astrocyte-dopaminergic neuron signaling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in astrocyte-dopaminergic neuron signaling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in bicellular tight junction assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in bone remodeling IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in bone resorption IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within bone resorption ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in branching involved in blood vessel morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within branching involved in blood vessel morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in branching involved in blood vessel morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in branching involved in ureteric bud morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within branching involved in ureteric bud morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within canonical Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in canonical Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in canonical Wnt signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell adhesion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cell adhesion NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell fate specification IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell fate specification ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell maturation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell maturation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cell morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cell-cell adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell-cell adhesion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cell-cell adhesion TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in cell-cell adhesion mediated by cadherin ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell-matrix adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to fibroblast growth factor stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in cellular response to growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to growth factor stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cellular response to indole-3-methanol IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to indole-3-methanol ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to indole-3-methanol ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cellular response to insulin-like growth factor stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in cellular response to insulin-like growth factor stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cellular response to lithium ion IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in cellular response to mechanical stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular response to zinc ion starvation IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in central nervous system vasculogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within central nervous system vasculogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within chemical synaptic transmission ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in chondrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of chondrocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cranial ganglion development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cranial ganglion development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cranial skeletal system development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cranial skeletal system development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in dorsal root ganglion development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in dorsal root ganglion development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in dorsal/ventral axis specification IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within dorsal/ventral axis specification ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within dorsal/ventral pattern formation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ectoderm development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within ectoderm development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in embryonic axis specification IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within embryonic axis specification ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in embryonic brain development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in embryonic brain development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in embryonic digit morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within embryonic digit morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in embryonic foregut morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within embryonic foregut morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in embryonic forelimb morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within embryonic forelimb morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in embryonic heart tube development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within embryonic heart tube development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in embryonic hindlimb morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within embryonic hindlimb morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in embryonic organ development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in embryonic skeletal limb joint morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in embryonic skeletal limb joint morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within endoderm formation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endodermal cell fate commitment IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within endodermal cell fate commitment ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endothelial tube morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endothelial tube morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endothelial tube morphogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in epididymis development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in epithelial cell differentiation involved in prostate gland development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within epithelial cell differentiation involved in prostate gland development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in epithelial cell proliferation involved in prostate gland development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of epithelial cell proliferation involved in prostate gland development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in epithelial tube branching involved in lung morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of epithelial tube branching involved in lung morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within epithelial tube branching involved in lung morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment of blood-brain barrier IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within establishment of blood-brain barrier ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment of blood-retinal barrier IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within establishment of blood-retinal barrier ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in fibroblast growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of fibroblast growth factor receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within forebrain development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in fungiform papilla formation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within fungiform papilla formation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in gastrulation with mouth forming second IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within gastrulation with mouth forming second ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in genitalia morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within genitalia morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within glandular epithelial cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glial cell fate determination IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within glial cell fate determination ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within hair cycle process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in hair follicle morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within hair follicle morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in hair follicle placode formation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within hair follicle placode formation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within heart development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within hemopoiesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in hindbrain development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in hindbrain development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in hypothalamus development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in hypothalamus development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in in utero embryonic development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within in utero embryonic development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within kidney development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in layer formation in cerebral cortex IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within layer formation in cerebral cortex ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in lens morphogenesis in camera-type eye IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within lens morphogenesis in camera-type eye ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within limb development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in liver development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    acts_upstream_of_or_within lung cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within lung development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in lung epithelial cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of lung epithelial cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in lung induction IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within lung induction ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in lung-associated mesenchyme development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within lung-associated mesenchyme development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in male genitalia development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within male genitalia development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of mesenchymal cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mesenchymal cell proliferation involved in lung development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mesenchymal cell proliferation involved in lung development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mesenchymal stem cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in metanephros morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within metanephros morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in midbrain development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in midbrain dopaminergic neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in midbrain dopaminergic neuron differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in midgut development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    acts_upstream_of_or_within morphogenesis of embryonic epithelium ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in myoblast differentiation IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in myoblast proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of myoblast proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within myoblast proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within negative regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of angiogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of angiogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within negative regulation of apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of canonical Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within negative regulation of cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of cell population proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of chondrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within negative regulation of chondrocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of mitotic cell cycle, embryonic IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of mitotic cell cycle, embryonic ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of mitotic cell cycle, embryonic ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of neurogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within negative regulation of neuron apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of oligodendrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within negative regulation of oligodendrocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of osteoclast differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within negative regulation of osteoclast differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of protein sumoylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of protein sumoylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of protein sumoylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nephron tubule formation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within nephron tubule formation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neural plate development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within neural plate development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neuroblast proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of neuroblast proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neuron differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neuron fate determination IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within neuron fate determination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neuron migration IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within neuron migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neuron projection extension IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in neuron projection extension ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neuron projection extension ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in odontogenesis of dentin-containing tooth IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in odontogenesis of dentin-containing tooth IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    acts_upstream_of_or_within odontogenesis of dentin-containing tooth ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in oligodendrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of oligodendrocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in oocyte development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within oocyte development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in osteoblast differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of osteoblast differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in osteoblast differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in osteoclast differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of osteoclast differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within osteoclast differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in outflow tract morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in outflow tract morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in oviduct development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within oviduct development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in pancreas development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within pancreas development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of branching involved in lung morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of branching involved in lung morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of determination of dorsal identity IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of determination of dorsal identity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of endothelial cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of endothelial cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of epithelial cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of epithelial cell proliferation involved in prostate gland development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of epithelial cell proliferation involved in prostate gland development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of epithelial to mesenchymal transition IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of epithelial to mesenchymal transition ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of epithelial to mesenchymal transition ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of fibroblast growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of fibroblast growth factor receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of heparan sulfate proteoglycan biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of heparan sulfate proteoglycan biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of heparan sulfate proteoglycan biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of mesenchymal cell proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of mesenchymal cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of molecular function ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of myoblast proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of myoblast proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of neural precursor cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of neuroblast proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of neuroblast proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of neuroblast proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of neuroblast proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of neuron apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of neuron apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of odontoblast differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of odontoblast differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of osteoblast differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of osteoblast differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of skeletal muscle tissue development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of skeletal muscle tissue development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of stem cell proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of stem cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of telomere maintenance via telomerase IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of positive regulation of telomere maintenance via telomerase ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of transcription elongation by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to cell surface IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein localization to cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to cell surface ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein polyubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in proximal/distal pattern formation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within proximal/distal pattern formation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of T cell proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within regulation of T cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of calcium ion import IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of calcium ion import ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of calcium ion import ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within regulation of cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of centriole-centriole cohesion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of centriole-centriole cohesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of centriole-centriole cohesion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of centromeric sister chromatid cohesion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of centromeric sister chromatid cohesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of centromeric sister chromatid cohesion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within regulation of epithelial cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of myelination IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within regulation of myelination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of nephron tubule epithelial cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of nephron tubule epithelial cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of osteoblast differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of osteoclast differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of protein localization to cell surface IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of protein localization to cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of protein localization to cell surface ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of secondary heart field cardioblast proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within regulation of secondary heart field cardioblast proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of smooth muscle cell proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of smooth muscle cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of smooth muscle cell proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of synapse assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of synapse assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of timing of anagen IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of timing of anagen ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in renal inner medulla development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within renal inner medulla development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in renal outer medulla development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within renal outer medulla development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in renal vesicle formation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within renal vesicle formation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to activity IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to cadmium ion IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to cytokine IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in response to estradiol IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to estradiol IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to estradiol ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to estradiol ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in response to estrogen IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in response to hormone IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to organic cyclic compound IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to xenobiotic stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to xenobiotic stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within skeletal system development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within skin development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in smooth muscle cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within smooth muscle cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in stem cell proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of stem cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sympathetic ganglion development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sympathetic ganglion development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sympathetic ganglion development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in synapse organization IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within synapse organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in synaptic vesicle clustering IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in synaptic vesicle clustering ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in synaptic vesicle transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within synaptic vesicle transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in thymus development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within thymus development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within tissue homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in trachea formation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within trachea formation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within trachea morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within vasculature development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within vasculogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of RNA polymerase II transcription regulator complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Schaffer collateral - CA1 synapse IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in Schaffer collateral - CA1 synapse ISO
    Inferred from Sequence Orthology
    more info
     
    part_of Scrib-APC-beta-catenin complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Scrib-APC-beta-catenin complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of Wnt signalosome IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Wnt signalosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Z disc IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Z disc ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in adherens junction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in adherens junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in adherens junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in apical junction complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in apical part of cell IEA
    Inferred from Electronic Annotation
    more info
     
    located_in apical part of cell ISO
    Inferred from Sequence Orthology
    more info
     
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in apicolateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in apicolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in basolateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of beta-catenin destruction complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of beta-catenin destruction complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of beta-catenin destruction complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of beta-catenin-ICAT complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of beta-catenin-ICAT complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of beta-catenin-TCF complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of beta-catenin-TCF7L2 complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of beta-catenin-TCF7L2 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of beta-catenin-TCF7L2 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in bicellular tight junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in bicellular tight junction ISO
    Inferred from Sequence Orthology
    more info
     
    part_of catenin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of catenin complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of catenin complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of catenin complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cell cortex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell cortex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell junction ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cell periphery ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell periphery ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cell projection membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell-cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell-cell junction ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centrosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendritic shaft IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in euchromatin IEA
    Inferred from Electronic Annotation
    more info
     
    located_in euchromatin ISO
    Inferred from Sequence Orthology
    more info
     
    located_in exocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in fascia adherens IEA
    Inferred from Electronic Annotation
    more info
     
    located_in fascia adherens ISO
    Inferred from Sequence Orthology
    more info
     
    part_of flotillin complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of flotillin complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intercalated disc IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in intercalated disc ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lamellipodium IEA
    Inferred from Electronic Annotation
    more info
     
    located_in lamellipodium ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lateral plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in lateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in lateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in microvillus membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in microvillus membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in postsynaptic density, intracellular component IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in postsynaptic density, intracellular component ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in postsynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in presynaptic active zone cytoplasmic component IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in presynaptic active zone cytoplasmic component ISO
    Inferred from Sequence Orthology
    more info
     
    located_in presynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in presynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-DNA complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of protein-DNA complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-DNA complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
     
    located_in synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in tight junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of transcription regulator complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of transcription regulator complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    catenin beta-1
    Names
    beta-catenin
    catenin (cadherin associated protein), beta 1, 88kDa

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431656.1NP_001418585.1  catenin beta-1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A0G2JT93, A6I428
    2. NM_001431662.1NP_001418591.1  catenin beta-1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A0G2JT93, A6I428
    3. NM_001431663.1NP_001418592.1  catenin beta-1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A0G2JT93, A6I428
    4. NM_001431664.1NP_001418593.1  catenin beta-1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A0G2JT93, A6I428
    5. NM_001431665.1NP_001418594.1  catenin beta-1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A0G2JT93, A6I428
    6. NM_001431666.1NP_001418595.1  catenin beta-1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A0G2JT93, A6I428
    7. NM_001431667.1NP_001418596.1  catenin beta-1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A0G2JT93, A6I428
    8. NM_001431668.1NP_001418597.1  catenin beta-1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A0G2JT93, A6I428
    9. NM_053357.3NP_445809.3  catenin beta-1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A0G2JT93, A6I428

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      129517576..129544661
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063266229.1XP_063122299.1  catenin beta-1 isoform X1

    2. XM_039082208.2XP_038938136.1  catenin beta-1 isoform X1

      Conserved Domains (4) summary
      smart00185
      Location:350390
      ARM; Armadillo/beta-catenin-like repeats
      COG5064
      Location:142431
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:402427
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:583622
      Arm; Armadillo/beta-catenin-like repeat
    3. XM_039082209.2XP_038938137.1  catenin beta-1 isoform X1

      Conserved Domains (4) summary
      smart00185
      Location:350390
      ARM; Armadillo/beta-catenin-like repeats
      COG5064
      Location:142431
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:402427
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:583622
      Arm; Armadillo/beta-catenin-like repeat
    4. XM_039082207.2XP_038938135.1  catenin beta-1 isoform X1

      Conserved Domains (4) summary
      smart00185
      Location:350390
      ARM; Armadillo/beta-catenin-like repeats
      COG5064
      Location:142431
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:402427
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:583622
      Arm; Armadillo/beta-catenin-like repeat
    5. XM_063266226.1XP_063122296.1  catenin beta-1 isoform X1

    6. XM_063266224.1XP_063122294.1  catenin beta-1 isoform X1

      Related
      ENSRNOP00000094665.2, ENSRNOT00000101345.2
    7. XM_063266227.1XP_063122297.1  catenin beta-1 isoform X1

    8. XM_063266225.1XP_063122295.1  catenin beta-1 isoform X1

    9. XM_063266228.1XP_063122298.1  catenin beta-1 isoform X1

      Related
      ENSRNOP00000068620.2, ENSRNOT00000079085.3