tmem251 transmembrane protein 251 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tmem251provided by ZNC
Official Full Name: transmembrane protein 251provided by ZNC
Primary source: ZFIN:ZDB-GENE-041001-121
See related: Ensembl:ENSDARG00000042341 AllianceGenome:ZFIN:ZDB-GENE-041001-121
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: gcaf; zgc:112233; si:dkeyp-55f12.4
Summary: Predicted to be involved in lysosome organization and regulation of vesicle-mediated transport. Predicted to be located in Golgi apparatus. Used to study mucolipidosis. Orthologous to human LYSET (lysosomal enzyme trafficking factor). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (27087539..27090853)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (27188454..27191763)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fd10d04.y1 (e-PCR)
- UniSTS:195104

fi73a12.y1 (e-PCR)
- UniSTS:197931

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in lysosome organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of vesicle-mediated transport	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi apparatus	ISS Inferred from Sequence or Structural Similarity more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: lysosomal enzyme trafficking factor

Names: UPF0694 transmembrane protein C14orf109 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.