ABCG19 white-brown complex homolog 19 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: ABCG19
Official Full Name: white-brown complex homolog 19
Primary source: TAIR:AT3G55130
Locus tag: AT3G55130
See related: Araport:AT3G55130
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATP-binding cassette G19; ATWBC19; WBC19; white-brown complex homolog 19
Summary: Encodes a vacuole localized protein of the ABC transporter White-Brown Complex (WBC) family. When overexpressed in planta, confers resistance to kanamycin.
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Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

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the antibiotic resistance gene WBC19 appears to also have a role in zinc uptake.
Title: RNA-seq analysis of the effect of kanamycin and the ABC transporter AtWBC19 on Arabidopsis thaliana seedlings reveals changes in metal content.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_115371.3

Function	Evidence Code	Pubs
enables ABC-type transporter activity	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables ATPase-coupled transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within vacuolar transport	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	ISM Inferred from Sequence Model more info
located_in vacuolar lumen	IDA Inferred from Direct Assay more info	PubMed

NP_191073.1

white-brown complex homolog 19 (WBC19); CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC-2 type transporter (InterPro:IPR013525), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: ABC-2 type transporter family protein (TAIR:AT3G55110.1); Has 390163 Blast hits to 355286 proteins in 4114 species: Archae - 7174; Bacteria - 309284; Metazoa - 8345; Fungi - 6290; Plants - 5468; Viruses - 12; Other Eukaryotes - 53590 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain