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    TCAF1 TRPM8 channel associated factor 1 [ Pongo abelii (Sumatran orangutan) ]

    Gene ID: 100173022, updated on 3-Dec-2024

    Summary

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    Gene symbol
    TCAF1
    Gene description
    TRPM8 channel associated factor 1
    Locus tag
    CR201_G0049604
    See related
    Ensembl:ENSPPYG00000018126
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pongo abelii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
    Also known as
    FAM115A
    Orthologs
    human mouse all
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    Genomic context

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    See TCAF1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 6 NC_071991.2 (141332195..141383313, complement)
    RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 7 NC_071992.1 (135153985..135205094, complement)

    Chromosome 6 - NC_071991.2Genomic Context describing neighboring genes Neighboring gene cTAGE family member 15 Neighboring gene TRPM8 channel associated factor 2 Neighboring gene uncharacterized LOC112134345 Neighboring gene uncharacterized LOC129060508 Neighboring gene olfactory receptor 2F2 Neighboring gene olfactory receptor 2F1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TRP channel-associated factors are a novel protein family that regulates TRPM8 trafficking and activity. Gkika D, et al. J Cell Biol, 2015 Jan 5. PMID 25559186, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • DKFZp469B1025

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables transmembrane transporter binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of anion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of protein targeting to membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TRPM8 channel-associated factor 1
    Names
    Protein FAM115A
    TRP channel-associated factor 1
    family with sequence similarity 115, member A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001132598.1 → NP_001126070.1  TRPM8 channel-associated factor 1

      See identical proteins and their annotated locations for NP_001126070.1

      Status: PROVISIONAL

      Source sequence(s)
      CR859688
      UniProtKB/TrEMBL
      A0A2J8RNF7, A0A8I5U2B9
      Conserved Domains (1) summary
      pfam13402
      Location:516 → 841
      Peptidase_M60; Peptidase M60, enhancin and enhancin-like

    RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Genomic

    1. NC_071991.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

      Range
      141332195..141383313 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009243355.4 → XP_009241630.3  TRPM8 channel-associated factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A2J8RNF4, H2PNW9

    2. XM_009243358.4 → XP_009241633.3  TRPM8 channel-associated factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A2J8RNF4, H2PNW9

    3. XM_009243360.4 → XP_009241635.3  TRPM8 channel-associated factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A2J8RNF4, H2PNW9

    4. XM_063725506.1 → XP_063581576.1  TRPM8 channel-associated factor 1 isoform X2

      UniProtKB/TrEMBL
      A0A2J8RNF7, A0A8I5U2B9

    5. XM_009243361.4 → XP_009241636.3  TRPM8 channel-associated factor 1 isoform X2

      UniProtKB/TrEMBL
      A0A2J8RNF7, A0A8I5U2B9

    6. XM_063725507.1 → XP_063581577.1  TRPM8 channel-associated factor 1 isoform X2

      UniProtKB/TrEMBL
      A0A2J8RNF7, A0A8I5U2B9

    7. XM_009243356.4 → XP_009241631.3  TRPM8 channel-associated factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A2J8RNF4, H2PNW9

    8. XM_063725505.1 → XP_063581575.1  TRPM8 channel-associated factor 1 isoform X2

      UniProtKB/TrEMBL
      A0A2J8RNF7, A0A8I5U2B9

    9. XM_009243359.4 → XP_009241634.3  TRPM8 channel-associated factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A2J8RNF4, H2PNW9

    10. XM_009243357.4 → XP_009241632.3  TRPM8 channel-associated factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A2J8RNF4, H2PNW9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5R8R3.2 GenPept UniProtKB/Swiss-Prot:Q5R8R3

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