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    Wdr25 WD repeat domain 25 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 314443, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Wdr25provided by RGD
    Official Full Name
    WD repeat domain 25provided by RGD
    Primary source
    RGD:1562505
    See related
    EnsemblRapid:ENSRNOG00000004733 AllianceGenome:RGD:1562505
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Wdr25l; RGD1562505; RGD1565864
    Summary
    Orthologous to human WDR25 (WD repeat domain 25). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 40.5), Spleen (RPKM 27.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Wdr25 in Genome Data Viewer
    Location:
    6q32
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (133571790..133704154)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (127807347..127939795)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (132802327..132932254)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 25, member 47 Neighboring gene tryptophanyl-tRNA synthetase 1 Neighboring gene brain-enriched guanylate kinase-associated Neighboring gene ribosomal protein S18, pseudogene 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC188413

    General protein information

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    Preferred Names
    WD repeat-containing protein 25

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135894.1 → NP_001129366.1  WD repeat-containing protein 25

      See identical proteins and their annotated locations for NP_001129366.1

      Status: PROVISIONAL

      Source sequence(s)
      BC166712
      UniProtKB/TrEMBL
      B2RYB0, F1LQP6
      Conserved Domains (2) summary
      cd00200
      Location:228 → 532
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:240 → 279
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      133571790..133704154
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063262013.1 → XP_063118083.1  WD repeat-containing protein 25 isoform X3

    2. XM_006240545.5 → XP_006240607.1  WD repeat-containing protein 25 isoform X1

      See identical proteins and their annotated locations for XP_006240607.1

      UniProtKB/TrEMBL
      B2RYB0, F1LQP6
      Related
      ENSRNOP00000006281.6, ENSRNOT00000006281.8
      Conserved Domains (2) summary
      cd00200
      Location:228 → 532
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:240 → 279
      7WD40; WD40 repeat [structural motif]

    3. XM_039112407.2 → XP_038968335.1  WD repeat-containing protein 25 isoform X1

      UniProtKB/TrEMBL
      B2RYB0, F1LQP6
      Conserved Domains (2) summary
      cd00200
      Location:228 → 532
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:240 → 279
      7WD40; WD40 repeat [structural motif]

    4. XM_006240546.5 → XP_006240608.1  WD repeat-containing protein 25 isoform X1

      See identical proteins and their annotated locations for XP_006240608.1

      UniProtKB/TrEMBL
      B2RYB0, F1LQP6
      Conserved Domains (2) summary
      cd00200
      Location:228 → 532
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:240 → 279
      7WD40; WD40 repeat [structural motif]

    5. XM_063262012.1 → XP_063118082.1  WD repeat-containing protein 25 isoform X2

    6. XM_039112408.1 → XP_038968336.1  WD repeat-containing protein 25 isoform X1

      UniProtKB/TrEMBL
      B2RYB0, F1LQP6
      Conserved Domains (2) summary
      cd00200
      Location:228 → 532
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:240 → 279
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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