Slco1a6 solute carrier organic anion transporter family, member 1a6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slco1a6provided by RGD
Official Full Name: solute carrier organic anion transporter family, member 1a6provided by RGD
Primary source: RGD:69304
See related: EnsemblRapid:ENSRNOG00000030894 AllianceGenome:RGD:69304
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Oatp5; Slc21a13
Summary: Predicted to enable bile acid transmembrane transporter activity and sodium-independent organic anion transmembrane transporter activity. Involved in animal organ regeneration. Predicted to be located in plasma membrane. Predicted to be active in basolateral plasma membrane. Orthologous to human SLCO1A2 (solute carrier organic anion transporter family member 1A2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 536.5) See more
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Genomic context

Location:: 4q44

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (176803025..176848311, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (175072143..175107950, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (176345671..176390729, complement)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AU046396 (e-PCR)
- UniSTS:115975

PMC19316P1 (e-PCR)
- UniSTS:271748

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables bile acid transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables sodium-independent organic anion transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in animal organ regeneration	IEP Inferred from Expression Pattern more info	PubMed
involved_in bile acid and bile salt transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in monoatomic ion transport	IEA Inferred from Electronic Annotation more info
involved_in sodium-independent organic anion transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in basolateral plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: solute carrier organic anion transporter family member 1A6

Names: OATP-5; kidney-specific organic anion transporting polypeptide 5; organic anion transporting polypeptide 5; solute carrier family (organic anion transporter) member 13; solute carrier family 21 member 13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_130736.1 → NP_570092.1 solute carrier organic anion transporter family member 1A6

See identical proteins and their annotated locations for NP_570092.1

Status: PROVISIONAL

Source sequence(s)

AF053317

UniProtKB/Swiss-Prot

Q9QYE2

UniProtKB/TrEMBL

A0A8L2UMB7, A6IMS9

Related

ENSRNOP00000039792.4, ENSRNOT00000048367.4

Conserved Domains (1) summary

TIGR00805
Location:1 → 625

oat; sodium-independent organic anion transporter

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086022.1 Reference GRCr8

Range

176803025..176848311 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063286766.1 → XP_063142836.1 solute carrier organic anion transporter family member 1A6 isoform X1

UniProtKB/TrEMBL

A0A8L2ULI3, A0A8L2UMB7
XM_063286767.1 → XP_063142837.1 solute carrier organic anion transporter family member 1A6 isoform X2

UniProtKB/TrEMBL

A0A8L2UMB7