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    Rimklb ribosomal modification protein rimK-like family member B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362428, updated on 9-Dec-2024

    Summary

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    Symbol
    Rimklbprovided by RGD
    Full Name
    ribosomal modification protein rimK-like family member Bprovided by RGD
    Primary source
    RGD:1560851
    See related
    EnsemblRapid:ENSRNOG00000064238 AllianceGenome:RGD:1560851
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Naags; Fam80b; RGD1560851
    Summary
    Predicted to enable N-acetyl-L-aspartate-L-glutamate ligase activity and citrate-L-glutamate ligase activity. Predicted to be involved in protein modification process. Predicted to be active in cytoplasm. Orthologous to human RIMKLB (ribosomal modification protein rimK like family member B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 74.0), Testes (RPKM 67.5) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rimklb in Genome Data Viewer
    Location:
    4q42
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (157336950..157396970, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (155664392..155706888, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (155258241..155292809, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene transfer RNA alanine (anticodon AGC) 5 Neighboring gene small ubiquitin-related modifier 1-like Neighboring gene microfibril associated protein 5 Neighboring gene U4 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Molecular characterization of N-acetylaspartylglutamate synthetase. Becker I, et al. J Biol Chem, 2010 Sep 17. PMID 20643647, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables N-acetyl-L-aspartate-L-glutamate ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables N-acetyl-L-aspartate-L-glutamate ligase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables citrate-L-glutamate ligase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein modification process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    beta-citrylglutamate synthase B
    Names
    N-acetylaspartyl-glutamate synthetase
    family with sequence similarity 80, member B
    ribosomal protein S6 modification-like protein B
    NP_001414785.1
    XP_006237377.1
    XP_006237378.1
    XP_006237379.1
    XP_063142406.1
    XP_063142407.1
    XP_063142408.1
    XP_063142409.1
    XP_063142410.1
    XP_063142411.1
    XP_063142412.1
    XP_063142413.1
    XP_063142414.1
    XP_063142415.1
    XP_063142416.1
    XP_063142417.1
    XP_063142418.1
    XP_063142419.1
    XP_342750.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427856.1 → NP_001414785.1  beta-citrylglutamate synthase B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A0A8I6A4B6, A0A8I6A9U5
      Related
      ENSRNOP00000085776.1, ENSRNOT00000115622.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      157336950..157396970 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063286340.1 → XP_063142410.1  beta-citrylglutamate synthase B isoform X1

      UniProtKB/TrEMBL
      A0A8I6A4B6, A0A8I6A9U5

    2. XM_063286336.1 → XP_063142406.1  beta-citrylglutamate synthase B isoform X1

      UniProtKB/TrEMBL
      A0A8I6A4B6, A0A8I6A9U5

    3. XM_063286349.1 → XP_063142419.1  beta-citrylglutamate synthase B isoform X3

    4. XM_063286338.1 → XP_063142408.1  beta-citrylglutamate synthase B isoform X1

      UniProtKB/TrEMBL
      A0A8I6A4B6, A0A8I6A9U5

    5. XM_063286342.1 → XP_063142412.1  beta-citrylglutamate synthase B isoform X2

      UniProtKB/TrEMBL
      A6ILE7

    6. XM_063286347.1 → XP_063142417.1  beta-citrylglutamate synthase B isoform X3

    7. XM_006237316.5 → XP_006237378.1  beta-citrylglutamate synthase B isoform X1

      See identical proteins and their annotated locations for XP_006237378.1

      UniProtKB/TrEMBL
      A0A8I6A4B6, A0A8I6A9U5
      Conserved Domains (1) summary
      TIGR00768
      Location:8 → 303
      rimK_fam; alpha-L-glutamate ligase, RimK family

    8. XM_063286341.1 → XP_063142411.1  beta-citrylglutamate synthase B isoform X1

      UniProtKB/TrEMBL
      A0A8I6A4B6, A0A8I6A9U5

    9. XM_063286339.1 → XP_063142409.1  beta-citrylglutamate synthase B isoform X1

      UniProtKB/TrEMBL
      A0A8I6A4B6, A0A8I6A9U5

    10. XM_063286345.1 → XP_063142415.1  beta-citrylglutamate synthase B isoform X2

      UniProtKB/TrEMBL
      A6ILE7

    11. XM_006237317.5 → XP_006237379.1  beta-citrylglutamate synthase B isoform X1

      See identical proteins and their annotated locations for XP_006237379.1

      UniProtKB/TrEMBL
      A0A8I6A4B6, A0A8I6A9U5
      Conserved Domains (1) summary
      TIGR00768
      Location:8 → 303
      rimK_fam; alpha-L-glutamate ligase, RimK family

    12. XM_063286343.1 → XP_063142413.1  beta-citrylglutamate synthase B isoform X2

      UniProtKB/TrEMBL
      A6ILE7

    13. XM_063286346.1 → XP_063142416.1  beta-citrylglutamate synthase B isoform X3

    14. XM_342749.10 → XP_342750.3  beta-citrylglutamate synthase B isoform X1

      See identical proteins and their annotated locations for XP_342750.3

      UniProtKB/TrEMBL
      A0A8I6A4B6, A0A8I6A9U5
      Conserved Domains (1) summary
      TIGR00768
      Location:8 → 303
      rimK_fam; alpha-L-glutamate ligase, RimK family

    15. XM_063286337.1 → XP_063142407.1  beta-citrylglutamate synthase B isoform X1

      UniProtKB/TrEMBL
      A0A8I6A4B6, A0A8I6A9U5

    16. XM_063286344.1 → XP_063142414.1  beta-citrylglutamate synthase B isoform X2

      UniProtKB/TrEMBL
      A6ILE7

    17. XM_063286348.1 → XP_063142418.1  beta-citrylglutamate synthase B isoform X3

    18. XM_006237315.4 → XP_006237377.1  beta-citrylglutamate synthase B isoform X1

      See identical proteins and their annotated locations for XP_006237377.1

      UniProtKB/TrEMBL
      A0A8I6A4B6, A0A8I6A9U5
      Conserved Domains (1) summary
      TIGR00768
      Location:8 → 303
      rimK_fam; alpha-L-glutamate ligase, RimK family
    Nucleotide Protein Strain
    Heading Accession and Version

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