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    Lcn8 lipocalin 8 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 366008, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lcn8provided by RGD
    Official Full Name
    lipocalin 8provided by RGD
    Primary source
    RGD:1306747
    See related
    EnsemblRapid:ENSRNOG00000017161 AllianceGenome:RGD:1306747
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306747
    Summary
    Predicted to enable small molecule binding activity. Predicted to act upstream of or within response to hormone. Predicted to be located in extracellular region. Orthologous to human LCN8 (lipocalin 8). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 5.1), Testes (RPKM 2.1) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Lcn8 in Genome Data Viewer
    Location:
    3p13
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (28866061..28869045)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (8467934..8473691)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (2871890..2875682)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 141 Neighboring gene ficolin A Neighboring gene lipocalin 5 Neighboring gene 60S ribosomal protein L34 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Gene duplication gives rise to a new 17-kilodalton lipocalin that shows epididymal region-specific expression and testicular factor(s) regulation. Lareyre JJ, et al. Endocrinology, 2001 Mar. PMID 11181548

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables small molecule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to hormone ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    epididymal-specific lipocalin-8
    Names
    epididymal 17 kDa protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001128183.1 → NP_001121655.1  epididymal-specific lipocalin-8 precursor

      See identical proteins and their annotated locations for NP_001121655.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474001
      UniProtKB/TrEMBL
      B3EY82, F7FKZ5
      Related
      ENSRNOP00000023062.4, ENSRNOT00000023062.7
      Conserved Domains (1) summary
      pfam00061
      Location:33 → 157
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      28866061..28869045
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006233632.4 → XP_006233694.3  epididymal-specific lipocalin-8 isoform X1

      Conserved Domains (1) summary
      cd19421
      Location:23 → 172
      lipocalin_5_8-like; lipocalin similar to human epididymal-specific lipocalin-8, mouse lipocalin-5 and -8, and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version

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