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    Tmem62 transmembrane protein 62 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 311350, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tmem62provided by RGD
    Official Full Name
    transmembrane protein 62provided by RGD
    Primary source
    RGD:1305647
    See related
    EnsemblRapid:ENSRNOG00000023874 AllianceGenome:RGD:1305647
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305647
    Summary
    Predicted to enable hydrolase activity. Predicted to be located in membrane. Orthologous to human TMEM62 (transmembrane protein 62). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 93.5), Liver (RPKM 83.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem62 in Genome Data Viewer
    Location:
    3q35
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (128380366..128415583)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (107921940..107961830)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (112915415..112950418)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120101914 Neighboring gene tau tubulin kinase 2 Neighboring gene uncharacterized LOC134486141 Neighboring gene ubiquitin protein ligase E3 component n-recognin 1 Neighboring gene cyclin D1 binding protein 1 Neighboring gene erythrocyte membrane protein band 4.2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 62

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398973.1 → NP_001385902.1  transmembrane protein 62

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      Conserved Domains (2) summary
      cd07401
      Location:57 → 345
      MPP_TMEM62_N; Homo sapiens TMEM62, N-terminal metallophosphatase domain
      pfam17957
      Location:340 → 391
      Big_7; Bacterial Ig domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      128380366..128415583
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039106818.2 → XP_038962746.1  transmembrane protein 62 isoform X1

      Related
      ENSRNOP00000086751.2, ENSRNOT00000102696.2
      Conserved Domains (2) summary
      cd07401
      Location:57 → 345
      MPP_TMEM62_N; Homo sapiens TMEM62, N-terminal metallophosphatase domain
      pfam17957
      Location:340 → 391
      Big_7; Bacterial Ig domain

    2. XM_039106820.2 → XP_038962748.1  transmembrane protein 62 isoform X2

      UniProtKB/TrEMBL
      A0A8I6A4E5
      Conserved Domains (2) summary
      cd07401
      Location:8 → 287
      MPP_TMEM62_N; Homo sapiens TMEM62, N-terminal metallophosphatase domain
      pfam17957
      Location:282 → 333
      Big_7; Bacterial Ig domain

    3. XM_039106822.1 → XP_038962750.1  transmembrane protein 62 isoform X3

      Conserved Domains (2) summary
      pfam17957
      Location:208 → 259
      Big_7; Bacterial Ig domain
      cl13995
      Location:28 → 213
      MPP_superfamily; metallophosphatase superfamily, metallophosphatase domain

    RNA

    1. XR_005502958.2 RNA Sequence

      Related
      ENSRNOT00000030065.8
    Nucleotide Protein Strain
    Heading Accession and Version

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