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    Cabcoco1 ciliary associated calcium binding coiled-coil 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361834, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cabcoco1provided by RGD
    Official Full Name
    ciliary associated calcium binding coiled-coil 1provided by RGD
    Primary source
    RGD:1306739
    See related
    EnsemblRapid:ENSRNOG00000000634 AllianceGenome:RGD:1306739
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306739
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be located in centrosome; cytoplasm; and sperm flagellum. Orthologous to human CABCOCO1 (ciliary associated calcium binding coiled-coil 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 202.3), Heart (RPKM 90.2) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cabcoco1 in Genome Data Viewer
    Location:
    20p11
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (20057462..20166732)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (20058492..20167973)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (21316770..21426036)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102546320 Neighboring gene uncharacterized LOC102546397 Neighboring gene ribosomal protein L5, pseudogene 4 Neighboring gene uncharacterized LOC102546480 Neighboring gene uncharacterized LOC102546554 Neighboring gene uncharacterized LOC134483790

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. CABCOCO1, a novel coiled-coil protein With calcium-binding activity, is localized in the sperm flagellum. Kawashima A, et al. Mol Reprod Dev, 2016 Oct. PMID 26990073

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium ion binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within sperm flagellum assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in sperm flagellum ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    ciliary-associated calcium-binding coiled-coil protein 1
    Names
    uncharacterized protein C10orf107 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134576.1 → NP_001128048.1  ciliary-associated calcium-binding coiled-coil protein 1

      See identical proteins and their annotated locations for NP_001128048.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473988
      UniProtKB/TrEMBL
      A0A8I5Y6I4, A6JKU4
      Conserved Domains (1) summary
      pfam14769
      Location:99 → 193
      CLAMP; Flagellar C1a complex subunit C1a-32

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      20057462..20166732
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006256355.4 → XP_006256417.1  ciliary-associated calcium-binding coiled-coil protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I5Y6I4, D3ZD36
      Related
      ENSRNOP00000000785.5, ENSRNOT00000000785.7
      Conserved Domains (1) summary
      pfam14769
      Location:93 → 187
      CLAMP; Flagellar C1a complex subunit C1a-32

    2. XM_006256356.5 → XP_006256418.1  ciliary-associated calcium-binding coiled-coil protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I5Y6I4, A0A8I6APL6
      Related
      ENSRNOP00000095689.1, ENSRNOT00000098928.2
      Conserved Domains (1) summary
      pfam14769
      Location:65 → 159
      CLAMP; Flagellar C1a complex subunit C1a-32

    3. XM_039098858.2 → XP_038954786.1  ciliary-associated calcium-binding coiled-coil protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I5Y6I4
      Related
      ENSRNOP00000077935.2, ENSRNOT00000103305.2
      Conserved Domains (1) summary
      pfam14769
      Location:59 → 155
      CLAMP; Flagellar C1a complex subunit C1a-32
    Nucleotide Protein Strain
    Heading Accession and Version

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