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    Fam13b family with sequence similarity 13, member B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291694, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fam13bprovided by RGD
    Official Full Name
    family with sequence similarity 13, member Bprovided by RGD
    Primary source
    RGD:1310484
    See related
    EnsemblRapid:ENSRNOG00000020384 AllianceGenome:RGD:1310484
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam13b1; RGD1310484
    Summary
    Predicted to be involved in signal transduction. Orthologous to human FAM13B (family with sequence similarity 13 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 207.8), Spleen (RPKM 196.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fam13b in Genome Data Viewer
    Location:
    18p12
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (26314440..26395260, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (26040285..26107112, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (27223345..27304462, complement)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene signal recognition particle 19, pseudogene 2 Neighboring gene receptor accessory protein 5 Neighboring gene polycystin 2 like 2, transient receptor potential cation channel Neighboring gene Set nuclear proto-oncogene, pseudogene 8 Neighboring gene Wnt family member 8A Neighboring gene uncharacterized LOC134482927 Neighboring gene NME/NM23 family member 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM13B
    Names
    family with sequence similarity 13, member B1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106158.1 → NP_001099628.1  protein FAM13B

      See identical proteins and their annotated locations for NP_001099628.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473974
      UniProtKB/TrEMBL
      A0A8I6G832, A6J2U4, D3ZJY0
      Related
      ENSRNOP00000027663.4, ENSRNOT00000027663.7
      Conserved Domains (1) summary
      cd04393
      Location:19 → 205
      RhoGAP_FAM13A1a; RhoGAP_FAM13A1a: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of FAM13A1, isoform a-like proteins. The function of FAM13A1a is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      26314440..26395260 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063277238.1 → XP_063133308.1  protein FAM13B isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZRM9, A0A8I6G832

    2. XM_063277236.1 → XP_063133306.1  protein FAM13B isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZRM9, A0A8I6G832

    3. XM_063277247.1 → XP_063133317.1  protein FAM13B isoform X5

      UniProtKB/TrEMBL
      A0A8I6G832

    4. XM_063277252.1 → XP_063133322.1  protein FAM13B isoform X6

      UniProtKB/TrEMBL
      A0A8I6A1J8, A0A8I6G832

    5. XM_063277239.1 → XP_063133309.1  protein FAM13B isoform X2

      UniProtKB/TrEMBL
      A0A8I6G832, A6J2U4, D3ZJY0

    6. XM_063277240.1 → XP_063133310.1  protein FAM13B isoform X2

      UniProtKB/TrEMBL
      A0A8I6G832, A6J2U4, D3ZJY0

    7. XM_063277245.1 → XP_063133315.1  protein FAM13B isoform X2

      UniProtKB/TrEMBL
      A0A8I6G832, A6J2U4, D3ZJY0

    8. XM_063277250.1 → XP_063133320.1  protein FAM13B isoform X6

      UniProtKB/TrEMBL
      A0A8I6A1J8, A0A8I6G832

    9. XM_063277243.1 → XP_063133313.1  protein FAM13B isoform X2

      UniProtKB/TrEMBL
      A0A8I6G832, A6J2U4, D3ZJY0

    10. XM_063277235.1 → XP_063133305.1  protein FAM13B isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZRM9, A0A8I6G832

    11. XM_063277246.1 → XP_063133316.1  protein FAM13B isoform X2

      UniProtKB/TrEMBL
      A0A8I6G832, A6J2U4, D3ZJY0

    12. XM_063277251.1 → XP_063133321.1  protein FAM13B isoform X6

      UniProtKB/TrEMBL
      A0A8I6A1J8, A0A8I6G832

    13. XM_039096730.2 → XP_038952658.1  protein FAM13B isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZRM9, A0A8I6G832
      Conserved Domains (2) summary
      cd04393
      Location:19 → 205
      RhoGAP_FAM13A1a; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of FAM13A1, isoform a-like proteins. The function of FAM13A1a is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their GTP-bound ...
      cl26235
      Location:813 → 852
      RecQL4_SLD2_NTD; N-terminal homeodomain-like domain of metazoan RecQ protein-like 4 (RecQL4), fungal DNA replication regulator SLD2 and similar proteins

    14. XM_063277241.1 → XP_063133311.1  protein FAM13B isoform X2

      UniProtKB/TrEMBL
      A0A8I6G832, A6J2U4, D3ZJY0

    15. XM_063277249.1 → XP_063133319.1  protein FAM13B isoform X6

      UniProtKB/TrEMBL
      A0A8I6A1J8, A0A8I6G832

    16. XM_039096731.2 → XP_038952659.1  protein FAM13B isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZRM9, A0A8I6G832
      Conserved Domains (2) summary
      cd04393
      Location:19 → 205
      RhoGAP_FAM13A1a; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of FAM13A1, isoform a-like proteins. The function of FAM13A1a is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their GTP-bound ...
      cl26235
      Location:813 → 852
      RecQL4_SLD2_NTD; N-terminal homeodomain-like domain of metazoan RecQ protein-like 4 (RecQL4), fungal DNA replication regulator SLD2 and similar proteins

    17. XM_039096733.2 → XP_038952661.1  protein FAM13B isoform X8

      Conserved Domains (1) summary
      cl26235
      Location:623 → 662
      RecQL4_SLD2_NTD; N-terminal homeodomain-like domain of metazoan RecQ protein-like 4 (RecQL4), fungal DNA replication regulator SLD2 and similar proteins

    18. XM_039096732.2 → XP_038952660.1  protein FAM13B isoform X8

      Conserved Domains (1) summary
      cl26235
      Location:623 → 662
      RecQL4_SLD2_NTD; N-terminal homeodomain-like domain of metazoan RecQ protein-like 4 (RecQL4), fungal DNA replication regulator SLD2 and similar proteins

    19. XM_063277253.1 → XP_063133323.1  protein FAM13B isoform X7

      UniProtKB/TrEMBL
      A0A8I6G832

    20. XM_008772033.4 → XP_008770255.1  protein FAM13B isoform X5

      UniProtKB/TrEMBL
      A0A8I6G832
      Conserved Domains (1) summary
      cd04393
      Location:19 → 205
      RhoGAP_FAM13A1a; RhoGAP_FAM13A1a: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of FAM13A1, isoform a-like proteins. The function of FAM13A1a is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active ...

    21. XM_063277248.1 → XP_063133318.1  protein FAM13B isoform X6

      UniProtKB/TrEMBL
      A0A8I6A1J8, A0A8I6G832
      Related
      ENSRNOP00000085511.1, ENSRNOT00000119847.2

    22. XM_008772031.4 → XP_008770253.1  protein FAM13B isoform X3

      UniProtKB/TrEMBL
      A0A8I6G832
      Conserved Domains (1) summary
      cd04393
      Location:19 → 205
      RhoGAP_FAM13A1a; RhoGAP_FAM13A1a: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of FAM13A1, isoform a-like proteins. The function of FAM13A1a is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active ...

    23. XM_008772032.4 → XP_008770254.1  protein FAM13B isoform X4

      UniProtKB/TrEMBL
      A0A8I6G832
      Conserved Domains (1) summary
      cd04393
      Location:19 → 205
      RhoGAP_FAM13A1a; RhoGAP_FAM13A1a: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of FAM13A1, isoform a-like proteins. The function of FAM13A1a is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active ...

    24. XM_017600914.3 → XP_017456403.1  protein FAM13B isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZRM9, A0A8I6G832
      Related
      ENSRNOP00000079749.1, ENSRNOT00000096309.2
      Conserved Domains (2) summary
      cd04393
      Location:19 → 205
      RhoGAP_FAM13A1a; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of FAM13A1, isoform a-like proteins. The function of FAM13A1a is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their GTP-bound ...
      cl26235
      Location:813 → 852
      RecQL4_SLD2_NTD; N-terminal homeodomain-like domain of metazoan RecQ protein-like 4 (RecQL4), fungal DNA replication regulator SLD2 and similar proteins

    25. XM_063277242.1 → XP_063133312.1  protein FAM13B isoform X2

      UniProtKB/TrEMBL
      A0A8I6G832, A6J2U4, D3ZJY0

    26. XM_063277237.1 → XP_063133307.1  protein FAM13B isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZRM9, A0A8I6G832

    27. XM_063277244.1 → XP_063133314.1  protein FAM13B isoform X2

      UniProtKB/TrEMBL
      A0A8I6G832, A6J2U4, D3ZJY0

    28. XM_039096734.1 → XP_038952662.1  protein FAM13B isoform X9

    Nucleotide Protein Strain
    Heading Accession and Version

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