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    B3galt5 Beta-1,3-galactosyltransferase 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288161, updated on 9-Dec-2024

    Summary

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    Official Symbol
    B3galt5provided by RGD
    Official Full Name
    Beta-1,3-galactosyltransferase 5provided by RGD
    Primary source
    RGD:1306727
    See related
    EnsemblRapid:ENSRNOG00000030983 AllianceGenome:RGD:1306727
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to act upstream of or within response to bacterium. Predicted to be active in Golgi membrane. Orthologous to human B3GALT5 (beta-1,3-galactosyltransferase 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 52.8), Brain (RPKM 24.4) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See B3galt5 in Genome Data Viewer
    Location:
    11q11
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (49053959..49100398)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (35584273..35630922)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (36638067..36683915)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene lebercilin LCA5 like Neighboring gene SH3 domain binding glutamate-rich protein Neighboring gene microRNA 6325 Neighboring gene immunoglobulin superfamily, member 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Association between expression levels of CA 19-9 and N-acetylglucosamine-beta;1,3-galactosyltransferase 5 gene in human pancreatic cancer tissue. Hayashi N, et al. Pathobiology, 2004. PMID 14555842
    2. Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins. Hu YH, et al. BMC Genomics, 2006 Jun 16. PMID 16780588, Free PMC Article
    3. Impact of lactobacilli on orally acquired listeriosis. Archambaud C, et al. Proc Natl Acad Sci U S A, 2012 Oct 9. PMID 23012479, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein O-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within response to bacterium ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    beta-1,3-galactosyltransferase 5
    Names
    UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
    NP_001099357.1
    XP_017453417.1
    XP_017453418.1
    XP_063126476.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105887.3 → NP_001099357.1  beta-1,3-galactosyltransferase 5

      See identical proteins and their annotated locations for NP_001099357.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A6KPR5, D4AB20
      Related
      ENSRNOP00000045319.3, ENSRNOT00000050178.6
      Conserved Domains (1) summary
      cl21608
      Location:69 → 259
      Galactosyl_T; Galactosyltransferase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      49053959..49100398
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063270406.1 → XP_063126476.1  beta-1,3-galactosyltransferase 5 isoform X1

      UniProtKB/TrEMBL
      A6KPR5, D4AB20
      Related
      ENSRNOP00000082456.1, ENSRNOT00000119017.2

    2. XM_017597929.3 → XP_017453418.1  beta-1,3-galactosyltransferase 5 isoform X1

      UniProtKB/TrEMBL
      A6KPR5, D4AB20
      Conserved Domains (1) summary
      cl21608
      Location:69 → 259
      Galactosyl_T; Galactosyltransferase

    3. XM_017597928.3 → XP_017453417.1  beta-1,3-galactosyltransferase 5 isoform X1

      UniProtKB/TrEMBL
      A6KPR5, D4AB20
      Related
      ENSRNOP00000106597.1, ENSRNOT00000163103.1
      Conserved Domains (1) summary
      cl21608
      Location:69 → 259
      Galactosyl_T; Galactosyltransferase
    Nucleotide Protein Strain
    Heading Accession and Version

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