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    Rps24 ribosomal protein S24 [ Mus musculus (house mouse) ]

    Gene ID: 20088, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rps24provided by MGI
    Official Full Name
    ribosomal protein S24provided by MGI
    Primary source
    MGI:MGI:98147
    See related
    Ensembl:ENSMUSG00000025290 AllianceGenome:MGI:98147
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    A structural constituent of ribosome. Predicted to be involved in erythrocyte homeostasis; rRNA processing; and ribosomal small subunit biogenesis. Predicted to act upstream of or within translation. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in embryo. Human ortholog(s) of this gene implicated in Diamond-blackfan anemia 3. Orthologous to human RPS24 (ribosomal protein S24). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 223.6), bladder adult (RPKM 143.0) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rps24 in Genome Data Viewer
    Location:
    14 A3; 14 14.42 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (24540786..24545925)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (24490678..24496960)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 47814 Neighboring gene polymerase (RNA) III (DNA directed) polypeptide A Neighboring gene STARR-seq mESC enhancer starr_36195 Neighboring gene predicted gene, 31720 Neighboring gene STARR-seq mESC enhancer starr_36198 Neighboring gene predicted gene, 31775 Neighboring gene STARR-seq mESC enhancer starr_36199 Neighboring gene STARR-seq mESC enhancer starr_36200 Neighboring gene STARR-seq mESC enhancer starr_36202 Neighboring gene predicted gene, 31951

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Nucleotide sequences of a cDNA clone encoding mouse ribosomal protein S24. Ro HS, et al. Nucleic Acids Res, 1991 Dec 11. PMID 1840675, Free PMC Article
    2. Development of Soft Tissue Sarcomas in Ribosomal Proteins L5 and S24 Heterozygous Mice. Kazerounian S, et al. J Cancer, 2016. PMID 26722357, Free PMC Article
    3. Molecular characterization of the mouse ribosomal protein S24 multigene family: a uniquely expressed intron-containing gene with cell-specific expression of three alternatively spliced mRNAs. Xu L, et al. Nucleic Acids Res, 1994 Feb 25. PMID 8127713, Free PMC Article
    4. The S29 ribosomal protein increases tumor suppressor activity of K rev-1 gene on v-K ras-transformed NIH3T3 cells. Kondoh N, et al. Biochim Biophys Acta, 1996 Aug 21. PMID 8781548
    5. Comparative genomics RNAi screen identifies Eftud2 as a novel regulator of innate immunity. De Arras L, et al. Genetics, 2014 Jun. PMID 24361939, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1)  1 citation

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC107549

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    enables translation initiation factor binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in erythrocyte homeostasis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in rRNA processing ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in ribosomal small subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in ribosomal small subunit biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within translation ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    involved_in translation at postsynapse NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in translation at presynapse NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    part_of cytosolic small ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in postsynapse NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in presynapse NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in ribosome NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of small-subunit processome ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of small-subunit processome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    small ribosomal subunit protein eS24
    Names
    40S ribosomal protein S24
    MRP S24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360584.2 → NP_001347513.1  small ribosomal subunit protein eS24 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      Q9D7P1, Q9DCA4
      Conserved Domains (1) summary
      PTZ00071
      Location:1 → 130
      PTZ00071; 40S ribosomal protein S24; Provisional

    2. NM_001360585.2 → NP_001347514.1  small ribosomal subunit protein eS24 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      Q9DCA4
      Conserved Domains (1) summary
      PTZ00071
      Location:1 → 130
      PTZ00071; 40S ribosomal protein S24; Provisional

    3. NM_001360586.2 → NP_001347515.1  small ribosomal subunit protein eS24 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC154573
      Consensus CDS
      CCDS88598.1
      UniProtKB/TrEMBL
      A0A286YEB7, Q9DCA4
      Related
      ENSMUSP00000153637.2, ENSMUST00000224568.2
      Conserved Domains (1) summary
      cl00878
      Location:1 → 118
      Ribosomal_S24e; Ribosomal protein S24e

    4. NM_001424557.1 → NP_001411486.1  small ribosomal subunit protein eS24 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      Q3TIF8, Q9CQK2, Q9CY61

    5. NM_001424558.1 → NP_001411487.1  small ribosomal subunit protein eS24 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      Q9DCA4

    6. NM_001424559.1 → NP_001411488.1  small ribosomal subunit protein eS24 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      Q9DCA4

    7. NM_001424560.1 → NP_001411489.1  small ribosomal subunit protein eS24 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      Q9DCA4

    8. NM_001424561.1 → NP_001411490.1  small ribosomal subunit protein eS24 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      Q9DCA4

    9. NM_001424562.1 → NP_001411491.1  small ribosomal subunit protein eS24 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      Q9CY61

    10. NM_001424563.1 → NP_001411492.1  small ribosomal subunit protein eS24 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      Q9CY61

    11. NM_001424564.1 → NP_001411493.1  small ribosomal subunit protein eS24 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      Q9CY61

    12. NM_001424565.1 → NP_001411494.1  small ribosomal subunit protein eS24 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      A0A286YEB7, Q9DCA4

    13. NM_001424566.1 → NP_001411495.1  small ribosomal subunit protein eS24 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      A0A286YEB7, Q9DCA4

    14. NM_001424567.1 → NP_001411496.1  small ribosomal subunit protein eS24 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      Q9DCA4

    15. NM_001424568.1 → NP_001411497.1  small ribosomal subunit protein eS24 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      Q9DCA4

    16. NM_001424569.1 → NP_001411498.1  small ribosomal subunit protein eS24 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      Q9DCA4

    17. NM_001424570.1 → NP_001411499.1  small ribosomal subunit protein eS24 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      Q9DCA4

    18. NM_001424571.1 → NP_001411500.1  small ribosomal subunit protein eS24 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC154573
      UniProtKB/TrEMBL
      Q9DCA4

    19. NM_011297.4 → NP_035427.2  small ribosomal subunit protein eS24 isoform 1

      See identical proteins and their annotated locations for NP_035427.2

      Status: VALIDATED

      Source sequence(s)
      AC154573
      Consensus CDS
      CCDS36830.1
      UniProtKB/TrEMBL
      Q9DCA4
      Related
      ENSMUSP00000125977.3, ENSMUST00000169826.3
      Conserved Domains (1) summary
      PTZ00071
      Location:1 → 130
      PTZ00071; 40S ribosomal protein S24; Provisional

    20. NM_207634.3 → NP_997517.1  small ribosomal subunit protein eS24 isoform 2

      See identical proteins and their annotated locations for NP_997517.1

      Status: VALIDATED

      Source sequence(s)
      AC154573
      Consensus CDS
      CCDS36829.1
      UniProtKB/Swiss-Prot
      P62849, Q642L0, Q6PDB5
      UniProtKB/TrEMBL
      Q3TIF8, Q5M9M7, Q9CY61
      Related
      ENSMUSP00000152944.2, ENSMUST00000225023.2
      Conserved Domains (1) summary
      PTZ00071
      Location:1 → 130
      PTZ00071; 40S ribosomal protein S24; Provisional

    21. NM_207635.3 → NP_997518.1  small ribosomal subunit protein eS24 isoform 3

      See identical proteins and their annotated locations for NP_997518.1

      Status: VALIDATED

      Source sequence(s)
      AC154573
      Consensus CDS
      CCDS88597.1
      UniProtKB/TrEMBL
      Q9DCA4
      Related
      ENSMUSP00000153659.2, ENSMUST00000223999.2
      Conserved Domains (1) summary
      PTZ00071
      Location:1 → 130
      PTZ00071; 40S ribosomal protein S24; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      24540786..24545925
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P62849.1 GenPept UniProtKB/Swiss-Prot:P62849

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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