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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001252565.2 → NP_001239494.1 nociceptin receptor isoform 1
See identical proteins and their annotated locations for NP_001239494.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate 5' non-coding exon; therefore, differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (1).
- Source sequence(s)
-
AL845173
- Consensus CDS
-
CCDS17222.1
- UniProtKB/Swiss-Prot
- P35377, Q60645, Q8VI74, Q9QUT5, Q9Z2M8, Q9Z2M9, Q9Z2N0
- UniProtKB/TrEMBL
- Q542U1, Q80WU7
- Related
- ENSMUSP00000104399.2, ENSMUST00000108768.8
- Conserved Domains (1) summary
-
- cd15092
Location:49 → 327
- 7tmA_NOFQ_opioid_R; nociceptin/orphanin FQ peptide receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
-
NM_001318919.1 → NP_001305848.1 nociceptin receptor isoform 1x
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the predominant transcript and encodes two isoforms, which result from the use of alternative in-frame translation termination codons. The shorter isoform (1) results from translation termination at the upstream UGA stop codon), while the longer isoform (1x) results from UGA stop codon readthrough to the downstream UAG termination codon. This RefSeq represents the longer, C-terminally extended isoform (1x). As the UGA stop codon has been reported to specify several alternative amino acids (tryptophan, cysteine, arginine and serine), the location of the upstream UGA stop codon in the longer isoform is denoted by an 'X'.
- Source sequence(s)
-
AL845173, BC050885, BY267034
- Consensus CDS
-
CCDS89611.1
- UniProtKB/TrEMBL
- A0A5F8MPZ9, Q80WU7
- Related
- ENSMUSP00000159197.2, ENSMUST00000238942.2
- Conserved Domains (1) summary
-
- cd15092
Location:49 → 327
- 7tmA_NOFQ_opioid_R; nociceptin/orphanin FQ peptide receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
-
NM_001318920.2 → NP_001305849.1 nociceptin receptor isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (3), also known as KOR-3d, uses an alternate, in-frame donor splice site at the first coding exon compared to variant 1. The resulting isoform (2) is shorter, missing a 5 aa protein segment compared to isoform 1. Variants 3 and 9 both encode the same isoform (2).
- Source sequence(s)
-
AL845173
- UniProtKB/TrEMBL
-
Q80WU7
- Conserved Domains (1) summary
-
- cd15092
Location:49 → 322
- 7tmA_NOFQ_opioid_R; nociceptin/orphanin FQ peptide receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
-
NM_001318922.2 → NP_001305851.1 nociceptin receptor isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (4), also known as KOR-3a, contains an additional internal exon, which results in translation initiation from an alternate start codon compared to variant 1. The encoded isoform (3) is shorter with a distinct N-terminus compared to isoform 1. Variants 4 and 10 both encode the same isoform (3).
- Source sequence(s)
-
AL845173
- Consensus CDS
-
CCDS84606.1
- UniProtKB/TrEMBL
-
B0R0C0
- Related
- ENSMUSP00000104394.2, ENSMUST00000108763.8
- Conserved Domains (2) summary
-
- cd14964
Location:70 → 91
- 7tm_GPCRs; TM helix 2 [structural motif]
- cl28897
Location:61 → 313
- 7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
-
NM_001318923.2 → NP_001305852.1 nociceptin receptor isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) uses an alternate donor splice site and contains an additional internal exon, which results in translation initiation from an alternate start codon compared to variant 1. The encoded isoform (4) is shorter with a distinct N-terminus compared to isoform 1.
- Source sequence(s)
-
AL845173
- Conserved Domains (2) summary
-
- cd14964
Location:65 → 86
- 7tm_GPCRs; TM helix 2 [structural motif]
- cl28897
Location:56 → 308
- 7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
-
NM_001318924.2 → NP_001305853.1 nociceptin receptor isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (6), also known as KOR-3b, contains an additional internal exon, which results in translation initiation from an in-frame, downstream start codon compared to variant 1. The encoded isoform (5) has a shorter N-terminus compared to isoform 1. Variants 6, 7, and 11-13 all encode the same isoform (5).
- Source sequence(s)
-
AL845173
- Conserved Domains (2) summary
-
- cd14964
Location:5 → 31
- 7tm_GPCRs; TM helix 2 [structural motif]
- cl28897
Location:1 → 249
- 7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
-
NM_001318925.2 → NP_001305854.1 nociceptin receptor isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (7), also known as KOR-3c, contains an additional internal exon, which results in translation initiation from an in-frame, downstream start codon compared to variant 1. The encoded isoform (5) has a shorter N-terminus compared to isoform 1. Variants 6, 7, and 11-13 all encode the same isoform (5).
- Source sequence(s)
-
AL845173
- Conserved Domains (2) summary
-
- cd14964
Location:5 → 31
- 7tm_GPCRs; TM helix 2 [structural motif]
- cl28897
Location:1 → 249
- 7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
-
NM_001420497.1 → NP_001407426.1 nociceptin receptor isoform 2
Status: REVIEWED
- Source sequence(s)
-
AL845173
- UniProtKB/TrEMBL
-
Q80WU7
-
NM_001420498.1 → NP_001407427.1 nociceptin receptor isoform 3
Status: REVIEWED
- Source sequence(s)
-
AL845173
- UniProtKB/TrEMBL
-
B0R0C0
-
NM_001420499.1 → NP_001407428.1 nociceptin receptor isoform 5
Status: REVIEWED
- Source sequence(s)
-
AL845173
-
NM_001420500.1 → NP_001407429.1 nociceptin receptor isoform 5
Status: REVIEWED
- Source sequence(s)
-
AL845173
-
NM_001420501.1 → NP_001407430.1 nociceptin receptor isoform 5
Status: REVIEWED
- Source sequence(s)
-
AL845173
-
NM_011012.6 → NP_035142.1 nociceptin receptor isoform 1
See identical proteins and their annotated locations for NP_035142.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the predominant transcript and encodes two isoforms, which result from the use of alternative in-frame translation termination codons. The shorter isoform (1) results from translation termination at the upstream UGA stop codon, while the longer isoform (1x) results from UGA stop codon readthrough to the downstream UAG termination codon. This RefSeq represents the shorter isoform (1). Variants 1 and 2 encode the same isoform.
- Source sequence(s)
-
AL845173
- Consensus CDS
-
CCDS17222.1
- UniProtKB/Swiss-Prot
- P35377, Q60645, Q8VI74, Q9QUT5, Q9Z2M8, Q9Z2M9, Q9Z2N0
- UniProtKB/TrEMBL
- Q542U1, Q80WU7
- Related
- ENSMUSP00000071513.4, ENSMUST00000071585.10
- Conserved Domains (1) summary
-
- cd15092
Location:49 → 327
- 7tmA_NOFQ_opioid_R; nociceptin/orphanin FQ peptide receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
RNA
-
NR_134926.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (8) lacks two consecutive internal exons compared to variant 1. It is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.
- Source sequence(s)
-
AL845173
- Related
-
ENSMUST00000126835.2
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000068.8 Reference GRCm39 C57BL/6J
- Range
-
181356585..181362778
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_030248361.2 → XP_030104221.1 nociceptin receptor isoform X3
- UniProtKB/TrEMBL
-
B0R0C0
- Conserved Domains (2) summary
-
- cd14964
Location:70 → 91
- 7tm_GPCRs; TM helix 2 [structural motif]
- cl28897
Location:61 → 313
- 7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
-
XM_017316325.2 → XP_017171814.1 nociceptin receptor isoform X1
- UniProtKB/Swiss-Prot
- P35377, Q60645, Q8VI74, Q9QUT5, Q9Z2M8, Q9Z2M9, Q9Z2N0
- UniProtKB/TrEMBL
- Q542U1, Q80WU7
- Conserved Domains (1) summary
-
- cd15092
Location:49 → 327
- 7tmA_NOFQ_opioid_R; nociceptin/orphanin FQ peptide receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
-
XM_036159470.1 → XP_036015363.1 nociceptin receptor isoform X2
- UniProtKB/TrEMBL
-
Q80WU7
- Conserved Domains (1) summary
-
- cd15092
Location:49 → 322
- 7tmA_NOFQ_opioid_R; nociceptin/orphanin FQ peptide receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
-
XM_036159475.1 → XP_036015368.1 nociceptin receptor isoform X4
- Conserved Domains (2) summary
-
- cd14964
Location:5 → 31
- 7tm_GPCRs; TM helix 2 [structural motif]
- cl28897
Location:1 → 249
- 7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
-
XM_030248365.2 → XP_030104225.1 nociceptin receptor isoform X4
- Conserved Domains (2) summary
-
- cd14964
Location:5 → 31
- 7tm_GPCRs; TM helix 2 [structural motif]
- cl28897
Location:1 → 249
- 7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
-
XM_036159476.1 → XP_036015369.1 nociceptin receptor isoform X4
- Conserved Domains (2) summary
-
- cd14964
Location:5 → 31
- 7tm_GPCRs; TM helix 2 [structural motif]
- cl28897
Location:1 → 249
- 7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
-
XM_017316330.1 → XP_017171819.1 nociceptin receptor isoform X4
- Conserved Domains (2) summary
-
- cd14964
Location:5 → 31
- 7tm_GPCRs; TM helix 2 [structural motif]
- cl28897
Location:1 → 249
- 7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
-
XM_030248366.1 → XP_030104226.1 nociceptin receptor isoform X4
- Conserved Domains (2) summary
-
- cd14964
Location:5 → 31
- 7tm_GPCRs; TM helix 2 [structural motif]
- cl28897
Location:1 → 249
- 7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily