Treml1 triggering receptor expressed on myeloid cells-like 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Treml1provided by RGD
Official Full Name: triggering receptor expressed on myeloid cells-like 1provided by RGD
Primary source: RGD:1565175
See related: EnsemblRapid:ENSRNOG00000040109 AllianceGenome:RGD:1565175
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1565175
Summary: Predicted to be involved in calcium-mediated signaling and platelet activation. Predicted to be located in several cellular components, including Golgi apparatus; nuclear speck; and platelet alpha granule. Orthologous to human TREML1 (triggering receptor expressed on myeloid cells like 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Spleen (RPKM 61.7), Lung (RPKM 9.1) and 1 other tissue See more
Orthologs: human all
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Genomic context

Location:: 9q12

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	9	NC_086027.1 (20133193..20139933, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	9	NC_051344.1 (12635584..12642324, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	9	NC_005108.4 (14597172..14603622, complement)

Chromosome 9 - NC_086027.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in calcium-mediated signaling	ISO Inferred from Sequence Orthology more info
involved_in platelet activation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
located_in cell surface	ISO Inferred from Sequence Orthology more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nuclear speck	IEA Inferred from Electronic Annotation more info
located_in nuclear speck	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
located_in platelet alpha granule	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: trem-like transcript 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001192001.2 → NP_001178930.1 trem-like transcript 1 protein isoform 1 precursor

Status: VALIDATED

Source sequence(s)

JAXUCZ010000009

UniProtKB/TrEMBL

D3ZYT6

Conserved Domains (2) summary

smart00410
Location:22 → 121

IG_like; Immunoglobulin like

cl11960
Location:24 → 106

Ig; Immunoglobulin domain
NM_001419518.1 → NP_001406447.1 trem-like transcript 1 protein isoform 2 precursor

Status: VALIDATED

Source sequence(s)

JAXUCZ010000009

Related

ENSRNOP00000018138.7, ENSRNOT00000018138.8