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    Dydc1 DPY30 domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 69496, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Dydc1provided by MGI
    Official Full Name
    DPY30 domain containing 1provided by MGI
    Primary source
    MGI:MGI:1916746
    See related
    Ensembl:ENSMUSG00000021790 AllianceGenome:MGI:1916746
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700029M23Rik
    Summary
    Predicted to be involved in epithelial cilium movement involved in extracellular fluid movement; flagellated sperm motility; and mating. Part of radial spoke. Orthologous to human DYDC1 (DPY30 domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 10.0) See more
    Orthologs
    human all
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    Genomic context

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    See Dydc1 in Genome Data Viewer
    Location:
    14 B; 14 22.36 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (40794834..40814154)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (41072880..41092197)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E8554 Neighboring gene predicted gene, 31839 Neighboring gene STARR-positive B cell enhancer ABC_E5429 Neighboring gene peroxiredoxin like 2A Neighboring gene STARR-seq mESC enhancer starr_36477 Neighboring gene DPY30 domain containing 2 Neighboring gene methionine adenosyltransferase 1A Neighboring gene surfactant associated protein A1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Differential requirements of IQUB for the assembly of radial spoke 1 and the motility of mouse cilia and flagella. Zhang X, et al. Cell Rep, 2022 Nov 22. PMID 36417862
    2. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Clone Names

    • MGC58375

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in epithelial cilium movement involved in extracellular fluid movement IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in flagellated sperm motility IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in mating IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in 9+2 motile cilium IC
    Inferred by Curator
    more info
    		 PubMed 
    part_of Set1C/COMPASS complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of radial spoke IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in sperm flagellum IC
    Inferred by Curator
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DPY30 domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001418554.1 → NP_001405483.1  DPY30 domain-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      AC154597
      UniProtKB/Swiss-Prot
      G3X8U6, Q810Q6, Q9D9T0

    2. NM_027094.2 → NP_081370.1  DPY30 domain-containing protein 1

      See identical proteins and their annotated locations for NP_081370.1

      Status: VALIDATED

      Source sequence(s)
      AC154597
      Consensus CDS
      CCDS49451.1
      UniProtKB/Swiss-Prot
      G3X8U6, Q810Q6, Q9D9T0
      Related
      ENSMUSP00000139412.2, ENSMUST00000189865.7
      Conserved Domains (2) summary
      pfam05186
      Location:1 → 42
      Dpy-30; Dpy-30 motif
      pfam06936
      Location:45 → 129
      Selenoprotein_S; Selenoprotein S (SelS)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      40794834..40814154
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017316179.1 → XP_017171668.1  DPY30 domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      E0CXB0
      Related
      ENSMUSP00000124785.2, ENSMUST00000161837.2
      Conserved Domains (2) summary
      pfam05186
      Location:1 → 42
      Dpy-30; Dpy-30 motif
      pfam06936
      Location:45 → 129
      Selenoprotein_S; Selenoprotein S (SelS)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D9T0.2 GenPept UniProtKB/Swiss-Prot:Q9D9T0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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