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    Rrh retinal pigment epithelium derived rhodopsin homolog [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310869, updated on 27-Dec-2024

    Summary

    Official Symbol
    Rrhprovided by RGD
    Official Full Name
    retinal pigment epithelium derived rhodopsin homologprovided by RGD
    Primary source
    RGD:1308948
    See related
    EnsemblRapid:ENSRNOG00000053349 AllianceGenome:RGD:1308948
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to be active in plasma membrane. Orthologous to human RRH (retinal pigment epithelium-derived rhodopsin homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 5.7), Brain (RPKM 4.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rrh in Genome Data Viewer
    Location:
    2q43
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (221036436..221048627, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (218362195..218374387, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (235237422..235250474, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene epidermal growth factor Neighboring gene leucine-rich repeat, Ig-like and transmembrane domains 3 Neighboring gene uncharacterized LOC134485966 Neighboring gene GAR1 ribonucleoprotein

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G protein-coupled photoreceptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cellular response to light stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in detection of visible light IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in phototransduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in visual perception IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    visual pigment-like receptor peropsin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107726.2NP_001101196.1  visual pigment-like receptor peropsin isoform 2

      See identical proteins and their annotated locations for NP_001101196.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A6HVP7, A6HVP8, D3ZY73
      Related
      ENSRNOP00000072493.1, ENSRNOT00000085096.3
      Conserved Domains (1) summary
      pfam00001
      Location:47197
      7tm_1; 7 transmembrane receptor (rhodopsin family)
    2. NM_001415060.1NP_001401989.1  visual pigment-like receptor peropsin isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A0A1W2Q6H2
      Related
      ENSRNOP00000076275.1, ENSRNOT00000093631.3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      221036436..221048627 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)