U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    LOC127891064 OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27738839-27739712 [ Homo sapiens (human) ]

    Gene ID: 127891064, updated on 12-Sep-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    LOC127891064
    Gene description
    OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27738839-27739712
    Gene type
    biological region
    Feature type(s)
    regulatory: enhancer
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors and is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See LOC127891064 in Genome Data Viewer
    Location:
    chromosome: 19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (27247931..27248804)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (29767550..29768423)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (27738839..27739712)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904678 Neighboring gene hepatitis A virus cellular receptor 1 pseudogene 1 Neighboring gene NANOG hESC enhancer GRCh37_chr19:24584392-24584893 Neighboring gene NANOG hESC enhancer GRCh37_chr19:24585417-24585918 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:24625458-24626443 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:24630995-24631601 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27732451-27733302 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27733303-27734155 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27734156-27735007 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:27735098-27735622 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27739713-27740586 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27737965-27738838 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27736489-27737057 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27735920-27736488 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:27737089-27737964 Neighboring gene NANOG hESC enhancer GRCh37_chr19:27808230-27808731 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:27812477-27813220 Neighboring gene NANOG hESC enhancer GRCh37_chr19:27813523-27814024 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:27814077-27814586 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:27836954-27837540 Neighboring gene NANOG hESC enhancer GRCh37_chr19:27844808-27845309 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:27874272-27875240 Neighboring gene NANOG hESC enhancer GRCh37_chr19:27875298-27875799 Neighboring gene NANOG hESC enhancer GRCh37_chr19:27877672-27878173 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:27894379-27895360 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:27897397-27897916 Neighboring gene uncharacterized LOC105372345 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14401 Neighboring gene long intergenic non-protein coding RNA 662 Neighboring gene long intergenic non-protein coding RNA 2987

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

    Go to the top of the page Help

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

    Go to the top of the page Help

    See Variation Viewer (GRCh37.p13)

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_140955.1 

      Range
      101..974
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      27247931..27248804
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      29767550..29768423
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases