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    Galr3 galanin receptor 3 [ Mus musculus (house mouse) ]

    Gene ID: 14429, updated on 27-Nov-2024

    Summary

    Official Symbol
    Galr3provided by MGI
    Official Full Name
    galanin receptor 3provided by MGI
    Primary source
    MGI:MGI:1329003
    See related
    Ensembl:ENSMUSG00000114755 AllianceGenome:MGI:1329003
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Galnr3
    Summary
    Predicted to enable galanin receptor activity and peptide hormone binding activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway; neuropeptide signaling pathway; and positive regulation of transcription by RNA polymerase II. Located in non-motile cilium. Orthologous to human GALR3 (galanin receptor 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in duodenum adult (RPKM 6.2), small intestine adult (RPKM 2.3) and 11 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Galr3 in Genome Data Viewer
    Location:
    15 E1; 15 37.7 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (78926085..78927758)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (79041885..79043558)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 17753 Neighboring gene STARR-positive B cell enhancer ABC_E7387 Neighboring gene H1.0 linker histone Neighboring gene glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase) Neighboring gene predicted gene 3924 Neighboring gene ankyrin repeat domain 54

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables galanin receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables galanin receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables galanin receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables peptide hormone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables peptide hormone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cilium ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in non-motile cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    galanin receptor type 3
    Names
    GAL3-R
    GALR-3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_015738.2NP_056553.2  galanin receptor type 3

      See identical proteins and their annotated locations for NP_056553.2

      Status: VALIDATED

      Source sequence(s)
      AL589670, BC131952
      Consensus CDS
      CCDS27631.1
      UniProtKB/Swiss-Prot
      A2RS28, E9QPX7, O88853
      Related
      ENSMUSP00000060517.4, ENSMUST00000058004.4
      Conserved Domains (2) summary
      cd14964
      Location:2044
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:18302
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      78926085..78927758
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)