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    YTHDC2 YTH domain containing 2 [ Gallus gallus (chicken) ]

    Gene ID: 415602, updated on 17-Aug-2024

    Summary

    Symbol
    YTHDC2provided by CGNC
    Full Name
    YTH domain containing 2provided by CGNC
    Primary source
    CGNC:106
    See related
    Ensembl:ENSGALG00010008243
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
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    Genomic context

    See YTHDC2 in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (46370811..46409153, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (46370811..46409153, complement)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene isochorismatase domain containing 1 Neighboring gene solute carrier family 27 (fatty acid transporter), member 6 Neighboring gene U2 spliceosomal RNA Neighboring gene mutated in colorectal cancers Neighboring gene decapping mRNA 2

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in intracellular anatomical structure IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    probable ATP-dependent RNA helicase YTHDC2; 3'-5' RNA helicase YTHDC2
    XP_004949328.1
    XP_025000689.1
    XP_046791805.1
    XP_046791806.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      46370811..46409153 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004949271.5XP_004949328.1  3'-5' RNA helicase YTHDC2 isoform X1

      Conserved Domains (9) summary
      cd06007
      Location:57115
      R3H_DEXH_helicase; R3H domain of a group of proteins which also contain a DEXH-box helicase domain, and may function as ATP-dependent DNA or RNA helicases. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine ...
      smart00847
      Location:827912
      HA2; Helicase associated domain (HA2) Add an annotation
      cd00046
      Location:221360
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00204
      Location:498583
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00271
      Location:621753
      Helicase_C; Helicase conserved C-terminal domain
      pfam04146
      Location:12961411
      YTH; YT521-B-like domain
      pfam07717
      Location:9501077
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
      pfam13637
      Location:520570
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:516548
      ANK; ANK repeat [structural motif]
    2. XM_025144921.3XP_025000689.1  3'-5' RNA helicase YTHDC2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Y1J8
      Related
      ENSGALP00010011264.1, ENSGALT00010019716.1
      Conserved Domains (4) summary
      cd06007
      Location:57115
      R3H_DEXH_helicase; R3H domain of a group of proteins which also contain a DEXH-box helicase domain, and may function as ATP-dependent DNA or RNA helicases. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine ...
      COG1643
      Location:2001019
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
      sd00045
      Location:516548
      ANK; ANK repeat [structural motif]
      pfam04146
      Location:12951426
      YTH; YT521-B-like domain

    RNA

    1. XR_005842652.2 RNA Sequence

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      46370811..46409153 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046935849.1XP_046791805.1  3'-5' RNA helicase YTHDC2 isoform X1

    2. XM_046935850.1XP_046791806.1  3'-5' RNA helicase YTHDC2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Y1J8

    RNA

    1. XR_006937577.1 RNA Sequence