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    LAX1 uncharacterized protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831866, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LAX1
    Official Full Name
    uncharacterized protein
    Primary source
    TAIR:AT5G01240
    Locus tag
    AT5G01240
    See related
    Araport:AT5G01240
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F7J8.220; F7J8_220; like AUXIN RESISTANT 1
    Summary
    Encodes LAX1 (LIKE AUXIN RESISTANT), a member of the AUX1 LAX family of auxin influx carriers. Required for the establishment of embryonic root cell organization.
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    Genomic context

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    See LAX1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Sequence:
    Chromosome: 5; NC_003076.8 (97536..101835)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene josephin-like protein Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene ncRNA Neighboring gene alpha 1,4-glycosyltransferase family protein Neighboring gene Carbohydrate-binding-like fold

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mechanistic insight into the role of AUXIN RESISTANCE4 in trafficking of AUXIN1 and LIKE AUX1-2. Tidy A, et al. Plant Physiol, 2023 Dec 30. PMID 37776522, Free PMC Article
    2. Auxin influx importers modulate serration along the leaf margin. Kasprzewska A, et al. Plant J, 2015 Aug. PMID 26111009, Free PMC Article
    3. AUX/LAX genes encode a family of auxin influx transporters that perform distinct functions during Arabidopsis development. Péret B, et al. Plant Cell, 2012 Jul. PMID 22773749, Free PMC Article
    4. Auxin influx carriers control vascular patterning and xylem differentiation in Arabidopsis thaliana. Fàbregas N, et al. PLoS Genet, 2015 Apr. PMID 25922946, Free PMC Article
    5. The bHLH protein ROX acts in concert with RAX1 and LAS to modulate axillary meristem formation in Arabidopsis. Yang F, et al. Plant J, 2012 Jul. PMID 22372440

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Mechanistic insight into the role of AUXIN RESISTANCE4 in trafficking of AUXIN1 and LIKE AUX1-2.
      Title: Mechanistic insight into the role of AUXIN RESISTANCE4 in trafficking of AUXIN1 and LIKE AUX1-2.
    2. Data report that three of these genes (AUX1, LAX1 and LAX2) show specific and dynamic patterns of expression during early leaf development
      Title: Auxin influx importers modulate serration along the leaf margin.
    3. we observed fewer and more spaced vascular bundles in quadruple mutants plants of the auxin influx carriers aux1lax1lax2lax3
      Title: Auxin influx carriers control vascular patterning and xylem differentiation in Arabidopsis thaliana.
    4. ROX encodes the LAX1/ba1 ortholog in Arabidopsis. ROX expression is regulated by LAS and RAX1.
      Title: The bHLH protein ROX acts in concert with RAX1 and LAS to modulate axillary meristem formation in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_120202.5
    NM_202990.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables auxin influx transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within root cap development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within somatic embryogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_195744.1
    • like AUXIN RESISTANT 1 (LAX1); CONTAINS InterPro DOMAIN/s: Amino acid transporter, transmembrane (InterPro:IPR013057); BEST Arabidopsis thaliana protein match is: Transmembrane amino acid transporter family protein (TAIR:AT2G38120.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_974719.1
    • like AUXIN RESISTANT 1 (LAX1); FUNCTIONS IN: transporter activity; INVOLVED IN: amino acid transport, root cap development; LOCATED IN: endomembrane system, membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Amino acid transporter, transmembrane (InterPro:IPR013057); BEST Arabidopsis thaliana protein match is: Transmembrane amino acid transporter family protein (TAIR:AT2G38120.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      97536..101835
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120202.5 → NP_195744.1  uncharacterized protein AT5G01240 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195744.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LFB2, Q9SMW2
      UniProtKB/TrEMBL
      A0A178UP16
      Conserved Domains (1) summary
      PLN03074
      Location:1 → 474
      PLN03074; auxin influx permease; Provisional

    2. NM_202990.2 → NP_974719.1  uncharacterized protein AT5G01240 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974719.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654FXP6, F4K7Z8
      Conserved Domains (1) summary
      PLN03074
      Location:1 → 394
      PLN03074; auxin influx permease; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LFB2.1

    Gene LinkOut

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