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    Cldnd2 claudin domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 74276, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cldnd2provided by MGI
    Official Full Name
    claudin domain containing 2provided by MGI
    Primary source
    MGI:MGI:1921526
    See related
    Ensembl:ENSMUSG00000038973 AllianceGenome:MGI:1921526
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700071E18Rik
    Summary
    Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human CLDND2 (claudin domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 34.5) See more
    Orthologs
    human all
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    Genomic context

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    See Cldnd2 in Genome Data Viewer
    Location:
    7 B3; 7 28.25 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (43090164..43093554)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (43440740..43444130)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene lens intrinsic membrane protein 2 Neighboring gene natural killer cell group 7 sequence Neighboring gene STARR-positive B cell enhancer ABC_E9689 Neighboring gene electron transferring flavoprotein, beta polypeptide Neighboring gene microRNA 7051 Neighboring gene predicted gene, 39000 Neighboring gene STARR-positive B cell enhancer ABC_E4923 Neighboring gene V-set and immunoglobulin domain containing 10 like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    claudin domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001418965.1 → NP_001405894.1  claudin domain-containing protein 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC149091, AC154108

    2. NM_028849.2 → NP_083125.1  claudin domain-containing protein 2 isoform 1

      See identical proteins and their annotated locations for NP_083125.1

      Status: VALIDATED

      Source sequence(s)
      AC149091, AC154108
      Consensus CDS
      CCDS39929.1
      UniProtKB/Swiss-Prot
      Q9D9H2
      UniProtKB/TrEMBL
      A1A539
      Related
      ENSMUSP00000037980.2, ENSMUST00000040227.3
      Conserved Domains (1) summary
      cl21598
      Location:23 → 144
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      43090164..43093554
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030243028.2 → XP_030098888.1  claudin domain-containing protein 2 isoform X2

      Conserved Domains (1) summary
      cl21598
      Location:23 → 144
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    2. XM_017312349.2 → XP_017167838.1  claudin domain-containing protein 2 isoform X1

      Conserved Domains (1) summary
      cl21598
      Location:23 → 140
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    3. XM_030243029.1 → XP_030098889.1  claudin domain-containing protein 2 isoform X3

      Conserved Domains (1) summary
      cl21598
      Location:23 → 140
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    4. XM_030243031.1 → XP_030098891.1  claudin domain-containing protein 2 isoform X5

      UniProtKB/Swiss-Prot
      Q9D9H2
      UniProtKB/TrEMBL
      A1A539
      Conserved Domains (1) summary
      cl21598
      Location:23 → 144
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    5. XM_030243030.1 → XP_030098890.1  claudin domain-containing protein 2 isoform X4

      Conserved Domains (1) summary
      cl21598
      Location:23 → 144
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D9H2.1 GenPept UniProtKB/Swiss-Prot:Q9D9H2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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