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    Ccdc163 coiled-coil domain containing 163 [ Mus musculus (house mouse) ]

    Gene ID: 68394, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ccdc163provided by MGI
    Official Full Name
    coiled-coil domain containing 163provided by MGI
    Primary source
    MGI:MGI:1915644
    See related
    Ensembl:ENSMUSG00000028689 AllianceGenome:MGI:1915644
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610037D15Rik; 4933430J04Rik
    Summary
    Is expressed in central nervous system and retina. Orthologous to human CCDC163 (CCDC163 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in testis adult (RPKM 19.0), bladder adult (RPKM 4.9) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ccdc163 in Genome Data Viewer
    Location:
    4 D1; 4 53.29 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (116565537..116572881)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (116708340..116715684)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 25137 Neighboring gene expressed sequence AV051173 Neighboring gene peroxiredoxin 1 Neighboring gene STARR-positive B cell enhancer ABC_E9593 Neighboring gene STARR-positive B cell enhancer ABC_E2706 Neighboring gene methylmalonic aciduria cblC type, with homocystinuria Neighboring gene STARR-positive B cell enhancer ABC_E37 Neighboring gene STARR-seq mESC enhancer starr_11147 Neighboring gene testis-specific kinase 2 Neighboring gene STARR-seq mESC enhancer starr_11148 Neighboring gene STARR-seq mESC enhancer starr_11149 Neighboring gene STARR-positive B cell enhancers ABC_E11715 and ABC_E10249 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:116480418-116480527 Neighboring gene target of EGR1, member 1 (nuclear) Neighboring gene mutY DNA glycosylase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Diversification of stem cell molecular repertoire by alternative splicing. Pritsker M, et al. Proc Natl Acad Sci U S A, 2005 Oct 4. PMID 16183747, Free PMC Article
    2. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein CCDC163

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356315.1 → NP_001343244.1  transmembrane protein CCDC163 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL683847, BE950263, BY248144, CD741104
      Conserved Domains (2) summary
      TIGR02169
      Location:158 → 303
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      TIGR04211
      Location:98 → 179
      SH3_and_anchor; SH3 domain protein

    2. NM_026714.3 → NP_080990.2  transmembrane protein CCDC163 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL683847, BE950263, BY248144, CD741104
      Consensus CDS
      CCDS38853.1
      UniProtKB/TrEMBL
      A2AGD7
      Related
      ENSMUSP00000102072.3, ENSMUST00000106464.3
      Conserved Domains (1) summary
      TIGR02169
      Location:145 → 290
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    RNA

    1. NR_151451.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL683847, BC022718, BE950263, BY248144

    2. NR_151452.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL683847, BC022733, BE950263, BY248144

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      116565537..116572881
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030253737.1 → XP_030109597.1  transmembrane protein CCDC163 isoform X10

      UniProtKB/TrEMBL
      A8Y5M9
      Conserved Domains (1) summary
      TIGR02169
      Location:28 → 173
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    2. XM_006503369.4 → XP_006503432.1  transmembrane protein CCDC163 isoform X12

    3. XM_017320378.3 → XP_017175867.1  transmembrane protein CCDC163 isoform X14

    4. XM_006503358.5 → XP_006503421.1  transmembrane protein CCDC163 isoform X1

      See identical proteins and their annotated locations for XP_006503421.1

      Conserved Domains (2) summary
      TIGR02168
      Location:81 → 254
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      TIGR02169
      Location:158 → 242
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    5. XM_006503363.5 → XP_006503426.1  transmembrane protein CCDC163 isoform X6

      Conserved Domains (1) summary
      TIGR04211
      Location:78 → 179
      SH3_and_anchor; SH3 domain protein

    6. XM_017320376.3 → XP_017175865.1  transmembrane protein CCDC163 isoform X7

      Conserved Domains (1) summary
      TIGR04211
      Location:78 → 179
      SH3_and_anchor; SH3 domain protein

    7. XM_006503368.4 → XP_006503431.1  transmembrane protein CCDC163 isoform X11

      UniProtKB/TrEMBL
      A2AGD6
      Conserved Domains (1) summary
      TIGR04211
      Location:78 → 179
      SH3_and_anchor; SH3 domain protein

    8. XM_006503360.5 → XP_006503423.1  transmembrane protein CCDC163 isoform X3

      Conserved Domains (1) summary
      TIGR02169
      Location:145 → 229
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    9. XM_030253740.2 → XP_030109600.1  transmembrane protein CCDC163 isoform X13

      UniProtKB/TrEMBL
      A2AGD6
      Related
      ENSMUSP00000120572.2, ENSMUST00000130828.8
      Conserved Domains (1) summary
      TIGR04211
      Location:85 → 166
      SH3_and_anchor; SH3 domain protein

    10. XM_030253736.2 → XP_030109596.1  transmembrane protein CCDC163 isoform X9

      UniProtKB/TrEMBL
      A2AGD6
      Conserved Domains (1) summary
      TIGR04211
      Location:65 → 166
      SH3_and_anchor; SH3 domain protein

    11. XM_006503359.4 → XP_006503422.1  transmembrane protein CCDC163 isoform X2

      Conserved Domains (2) summary
      TIGR02168
      Location:80 → 253
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      TIGR02169
      Location:157 → 241
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    12. XM_006503361.4 → XP_006503424.1  transmembrane protein CCDC163 isoform X4

      Conserved Domains (2) summary
      TIGR02168
      Location:67 → 240
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      TIGR02169
      Location:144 → 228
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    13. XM_036164389.1 → XP_036020282.1  transmembrane protein CCDC163 isoform X5

    14. XM_036164391.1 → XP_036020284.1  transmembrane protein CCDC163 isoform X10

      UniProtKB/TrEMBL
      A8Y5M9
      Conserved Domains (1) summary
      TIGR02169
      Location:28 → 173
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    15. XM_017320377.3 → XP_017175866.1  transmembrane protein CCDC163 isoform X8

      Conserved Domains (1) summary
      TIGR02169
      Location:28 → 112
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    16. XM_006503365.4 → XP_006503428.1  transmembrane protein CCDC163 isoform X8

      Conserved Domains (1) summary
      TIGR02169
      Location:28 → 112
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    17. XM_030253738.2 → XP_030109598.1  transmembrane protein CCDC163 isoform X10

      UniProtKB/TrEMBL
      A8Y5M9
      Related
      ENSMUSP00000102070.3, ENSMUST00000106462.9
      Conserved Domains (1) summary
      TIGR02169
      Location:28 → 173
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    18. XM_036164390.1 → XP_036020283.1  transmembrane protein CCDC163 isoform X8

      Conserved Domains (1) summary
      TIGR02169
      Location:28 → 112
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    RNA

    1. XR_003955004.2 RNA Sequence

    2. XR_376350.4 RNA Sequence

    3. XR_001784191.3 RNA Sequence

    4. XR_003955003.2 RNA Sequence

    5. XR_003955001.2 RNA Sequence

      Related
      ENSMUST00000030452.13

    6. XR_004941952.1 RNA Sequence

    7. XR_001784194.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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