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    Ank3 ankyrin 3, epithelial [ Mus musculus (house mouse) ]

    Gene ID: 11735, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ank3provided by MGI
    Official Full Name
    ankyrin 3, epithelialprovided by MGI
    Primary source
    MGI:MGI:88026
    See related
    Ensembl:ENSMUSG00000069601 AllianceGenome:MGI:88026
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AnkG; Ank-3; Ankyrin-3; Ankyrin-G; 2900054D09Rik
    Summary
    This gene encodes a member of the ankyrin protein family. Ankyrins link integral membrane proteins to the spectrin-based cytoskeleton. Ankyrin family members share a protein structure which includes three independently folded domains: the N-terminal ankyrin repeat domain, the central spectrin-binding domain, and the C-terminal rod domain. This ankyrin functions as the major ankyrin in the kidney and may play a role in the polarized distribution of many integral membrane proteins to specific subcellular sites. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
    Expression
    Broad expression in cerebellum adult (RPKM 12.9), CNS E18 (RPKM 10.5) and 16 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ank3 in Genome Data Viewer
    Location:
    10 B5.3; 10 36.1 cM
    Exon count:
    57
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (69234608..69863266)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (69533486..70027436)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930423B08 gene Neighboring gene STARR-positive B cell enhancer ABC_E6871 Neighboring gene STARR-seq mESC enhancer starr_27056 Neighboring gene cyclin dependent kinase 1 Neighboring gene STARR-seq mESC enhancer starr_27058 Neighboring gene suppression of tumorigenicity 13 pseudogene Neighboring gene STARR-seq mESC enhancer starr_27059 Neighboring gene predicted gene, 51806 Neighboring gene predicted gene, 33464 Neighboring gene 60S ribosomal protein L36 pseudogene Neighboring gene STARR-seq mESC enhancer starr_27062 Neighboring gene STARR-seq mESC enhancer starr_27063 Neighboring gene predicted gene, 33416 Neighboring gene predicted gene, 33361 Neighboring gene STARR-seq mESC enhancer starr_27068 Neighboring gene STARR-seq mESC enhancer starr_27069 Neighboring gene STARR-positive B cell enhancer ABC_E5146 Neighboring gene STARR-seq mESC enhancer starr_27073 Neighboring gene predicted gene, 51771 Neighboring gene coiled-coil domain containing 6 Neighboring gene myoregulin

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (5) 
    • Gene trapped (1) 
    • Targeted (8)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC14049

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cadherin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables cadherin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables cytoskeletal protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables cytoskeletal protein binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables phosphorylation-dependent protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein-macromolecule adaptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-macromolecule adaptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables spectrin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables spectrin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables structural constituent of cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    enables transmembrane transporter binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transmembrane transporter binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transmembrane transporter binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane protein transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in anterograde axonal transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in axon development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cellular response to magnesium ion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in clustering of voltage-gated sodium channels ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment of protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment or maintenance of microtubule cytoskeleton polarity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in magnesium ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in maintenance of protein location in cell ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in maintenance of protein location in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in membrane assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in membrane assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mitotic cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of delayed rectifier potassium channel activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neuromuscular junction development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in neuronal action potential IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in plasma membrane organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of action potential TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in positive regulation of cation channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of cell communication by electrical coupling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cell communication by electrical coupling ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of gene expression ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of homotypic cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of homotypic cell-cell adhesion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of membrane depolarization during cardiac muscle cell action potential ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of membrane depolarization during cardiac muscle cell action potential ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of membrane potential ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of membrane potential ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of non-canonical NF-kappaB signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of protein targeting to membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of protein targeting to membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of sodium ion import across plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of sodium ion transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of sodium ion transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of sodium ion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within protein localization to axon IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein localization to axon ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to axon ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein localization to plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein localization to plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein localization to plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of potassium ion transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of potassium ion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of protein targeting ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in synapse organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within synapse organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in T-tubule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in T-tubule ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in Z disc ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Z disc ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in axon ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in axon initial segment IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in axon initial segment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in axon initial segment IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in axon initial segment ISO
    Inferred from Sequence Orthology
    more info
     
    located_in basal plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with bicellular tight junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell surface ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in costamere ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendrite ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in intercalated disc IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in intercalated disc ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in neuromuscular junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in neuromuscular junction ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in node of Ranvier IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in node of Ranvier ISO
    Inferred from Sequence Orthology
    more info
     
    located_in paranode region of axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in postsynapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in postsynaptic density IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in postsynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynaptic membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in sarcolemma ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sarcolemma ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in sarcoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sarcoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in spectrin-associated cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    located_in spectrin-associated cytoskeleton ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    ankyrin-3
    Names
    brain-specific ankyrin-G

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009670.4NP_033800.2  ankyrin-3 isoform g

      See identical proteins and their annotated locations for NP_033800.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) utilizes an alternate exon in the 5' coding region and an alternate translation initiation site, compared to variant 2. This results in a shorter isoform (g) and distinct N-terminus, compared to isoform b.
      Source sequence(s)
      AC132435, L40631
      Consensus CDS
      CCDS59546.1
      UniProtKB/TrEMBL
      S4R1X7
      Related
      ENSMUSP00000138285.2, ENSMUST00000181974.8
      Conserved Domains (2) summary
      smart00218
      Location:116220
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:609692
      Death_ank3; Death domain of Ankyrin-3
    2. NM_146005.3NP_666117.2  ankyrin-3 isoform b

      See identical proteins and their annotated locations for NP_666117.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) represents the longest transcript and encodes the longest isoform (b).
      Source sequence(s)
      AC129018, AC132435, AC156836, L40632
      Consensus CDS
      CCDS23909.1
      UniProtKB/Swiss-Prot
      G5E8K4, G5E8K5, O08866, O08867, Q3TSJ8, Q4U205, Q4U206, Q4U256, Q4U260, Q61305, Q61306, Q61307, Q61308, Q61309, Q61310, Q8CBN3, Q8VC68
      Related
      ENSMUSP00000138326.2, ENSMUST00000182884.8
      Conserved Domains (7) summary
      smart00218
      Location:9831087
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14761559
      Death_ank3; Death domain of Ankyrin-3
      cd00204
      Location:443568
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:453544
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:614667
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:732786
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:448479
      ANK; ANK repeat [structural motif]
    3. NM_170687.3NP_733788.2  ankyrin-3 isoform f

      See identical proteins and their annotated locations for NP_733788.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) utilizes an alternate exon in the 5' coding region and an alternate translation initiation site, compared to variant 2. This results in a shorter isoform (f) and distinct N-terminus, compared to isoform b.
      Source sequence(s)
      AC132435, AC156836, L40631
      Consensus CDS
      CCDS23912.1
      UniProtKB/TrEMBL
      S4R236
      Related
      ENSMUSP00000090089.5, ENSMUST00000092433.12
      Conserved Domains (2) summary
      smart00218
      Location:116220
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:609692
      Death_ank3; Death domain of Ankyrin-3
    4. NM_170688.2NP_733789.1  ankyrin-3 isoform c

      See identical proteins and their annotated locations for NP_733789.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame segment in the coding region, compared to variant 2. This results in a shorter isoform (c), compared to isoform b.
      Source sequence(s)
      AC129018, AC132435, AC156836, L40632
      UniProtKB/Swiss-Prot
      G5E8K5
      Conserved Domains (7) summary
      smart00218
      Location:9831087
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14761559
      Death_ank3; Death domain of Ankyrin-3
      cd00204
      Location:443568
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:453544
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:614667
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:732786
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:448479
      ANK; ANK repeat [structural motif]
    5. NM_170689.2NP_733790.2  ankyrin-3 isoform d

      See identical proteins and their annotated locations for NP_733790.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks an alternate in-frame exon in the coding region, compared to variant 2. This results in a shorter isoform (d), compared to isoform b.
      Source sequence(s)
      AC129018, AC132435, AC156836, L40632
      Consensus CDS
      CCDS48590.1
      UniProtKB/TrEMBL
      G5E8K3
      Related
      ENSMUSP00000090088.6, ENSMUST00000092432.12
      Conserved Domains (7) summary
      smart00218
      Location:9651069
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14581541
      Death_ank3; Death domain of Ankyrin-3
      cd00204
      Location:443568
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:453544
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:614667
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:732786
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:448479
      ANK; ANK repeat [structural motif]
    6. NM_170690.2NP_733791.2  ankyrin-3 isoform e

      See identical proteins and their annotated locations for NP_733791.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) lacks an alternate in-frame exon in the coding region, compared to variant 2. This results in a shorter isoform (e), compared to isoform b.
      Source sequence(s)
      AC129018, AC132435, AC156836, L40632
      Consensus CDS
      CCDS23910.1
      UniProtKB/TrEMBL
      G5E8K2
      Related
      ENSMUSP00000090087.6, ENSMUST00000092431.12
      Conserved Domains (7) summary
      smart00218
      Location:9621066
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14551538
      Death_ank3; Death domain of Ankyrin-3
      cd00204
      Location:443568
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:453544
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:614667
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:732786
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:448479
      ANK; ANK repeat [structural motif]
    7. NM_170728.2NP_733924.2  ankyrin-3 isoform a

      See identical proteins and their annotated locations for NP_733924.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) has multiple differences in the coding region but maintains the reading frame, compared to variant 2. The encoded isoform (a) is shorter, compared to isoform b.
      Source sequence(s)
      AC129018, AC132435, AC156836, L40632
      Consensus CDS
      CCDS59545.1
      UniProtKB/Swiss-Prot
      G5E8K5
      Related
      ENSMUSP00000138347.2, ENSMUST00000182155.8
      Conserved Domains (7) summary
      smart00218
      Location:9441048
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14371520
      Death_ank3; Death domain of Ankyrin-3
      cd00204
      Location:443568
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:453544
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:614667
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:732786
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:448479
      ANK; ANK repeat [structural motif]
    8. NM_170729.2NP_733925.2  ankyrin-3 isoform h

      See identical proteins and their annotated locations for NP_733925.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) has multiple differences in the coding region but maintains the reading frame, compared to variant 2. This results in a shorter isoform (h), compared to isoform b.
      Source sequence(s)
      AC129018, AC132435, AC156836, L40632
      Consensus CDS
      CCDS35931.1
      UniProtKB/Swiss-Prot
      G5E8K5
      Related
      ENSMUSP00000061698.9, ENSMUST00000054167.15
      Conserved Domains (7) summary
      smart00218
      Location:9441048
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14371520
      Death_ank3; Death domain of Ankyrin-3
      cd00204
      Location:443568
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:453544
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:614667
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:732786
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:448479
      ANK; ANK repeat [structural motif]
    9. NM_170730.2NP_733926.2  ankyrin-3 isoform i

      See identical proteins and their annotated locations for NP_733926.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) lacks an in-frame segment in the 5' coding region and an in-frame segment in the 3' coding region, compared to variant 2. This results in a shorter isoform (i), compared to isoform b.
      Source sequence(s)
      AC129018, AC132435, L40632
      Consensus CDS
      CCDS23911.1
      UniProtKB/TrEMBL
      G3X971, Q9QXH1
      Related
      ENSMUSP00000138356.2, ENSMUST00000182439.8
      Conserved Domains (2) summary
      smart00218
      Location:56160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:549632
      Death_ank3; Death domain of Ankyrin-3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      69234608..69863266
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036155552.1XP_036011445.1  ankyrin-3 isoform X36

      UniProtKB/TrEMBL
      A0A1W2P812
      Related
      ENSMUSP00000151906.2, ENSMUST00000218680.2
      Conserved Domains (7) summary
      smart00218
      Location:9761080
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14691552
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:363651
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:459490
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:757809
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13021431
      UPA_2; UPA domain
      cl39094
      Location:545782
      Ank_2; Ankyrin repeats (3 copies)
    2. XM_036155538.1XP_036011431.1  ankyrin-3 isoform X19

      Conserved Domains (7) summary
      smart00218
      Location:9661070
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14681551
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:363651
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:459490
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:757809
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12921421
      UPA_2; UPA domain
      cl39094
      Location:545782
      Ank_2; Ankyrin repeats (3 copies)
    3. XM_036155553.1XP_036011446.1  ankyrin-3 isoform X37

      Conserved Domains (7) summary
      smart00218
      Location:9661070
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14681551
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:363651
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:459490
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:757809
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12921421
      UPA_2; UPA domain
      cl39094
      Location:545782
      Ank_2; Ankyrin repeats (3 copies)
    4. XM_036155554.1XP_036011447.1  ankyrin-3 isoform X38

      Conserved Domains (7) summary
      smart00218
      Location:9661070
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14681551
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:363651
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:459490
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:757809
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12921421
      UPA_2; UPA domain
      cl39094
      Location:545782
      Ank_2; Ankyrin repeats (3 copies)
    5. XM_036155557.1XP_036011450.1  ankyrin-3 isoform X42

      Conserved Domains (7) summary
      smart00218
      Location:9551059
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14481531
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:363651
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:459490
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:757809
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12811410
      UPA_2; UPA domain
      cl39094
      Location:545782
      Ank_2; Ankyrin repeats (3 copies)
    6. XM_036155521.1XP_036011414.1  ankyrin-3 isoform X1

      Conserved Domains (9) summary
      smart00218
      Location:10181155
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:41134196
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      pfam05109
      Location:15421949
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam11081
      Location:32963412
      DUF2890; Protein of unknown function (DUF2890)
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13771506
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    7. XM_036155522.1XP_036011415.1  ankyrin-3 isoform X2

      Conserved Domains (9) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:41184201
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      pfam05109
      Location:15471954
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam11081
      Location:33013417
      DUF2890; Protein of unknown function (DUF2890)
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    8. XM_036155523.1XP_036011416.1  ankyrin-3 isoform X3

      Conserved Domains (9) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:41184201
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      pfam05109
      Location:15471954
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam11081
      Location:33013417
      DUF2890; Protein of unknown function (DUF2890)
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    9. XM_036155525.1XP_036011418.1  ankyrin-3 isoform X5

      Conserved Domains (9) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:41184201
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      pfam05109
      Location:15471954
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam11081
      Location:33013417
      DUF2890; Protein of unknown function (DUF2890)
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    10. XM_036155526.1XP_036011419.1  ankyrin-3 isoform X6

      Conserved Domains (9) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:36893772
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      pfam05109
      Location:15471954
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam11081
      Location:33013417
      DUF2890; Protein of unknown function (DUF2890)
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    11. XM_036155524.1XP_036011417.1  ankyrin-3 isoform X4

      Conserved Domains (9) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:41184201
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      pfam05109
      Location:15471954
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam11081
      Location:33013417
      DUF2890; Protein of unknown function (DUF2890)
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    12. XM_036155527.1XP_036011420.1  ankyrin-3 isoform X7

      Conserved Domains (9) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:36893772
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      pfam05109
      Location:15471954
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam11081
      Location:33013417
      DUF2890; Protein of unknown function (DUF2890)
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    13. XM_036155528.1XP_036011421.1  ankyrin-3 isoform X8

      Conserved Domains (9) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:36893772
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      pfam05109
      Location:15471954
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam11081
      Location:33013417
      DUF2890; Protein of unknown function (DUF2890)
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    14. XM_036155529.1XP_036011422.1  ankyrin-3 isoform X9

      Conserved Domains (8) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:24082491
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      pfam05109
      Location:15471954
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    15. XM_036155530.1XP_036011423.1  ankyrin-3 isoform X10

      Conserved Domains (8) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:24082491
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      pfam05109
      Location:15471954
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    16. XM_036155531.1XP_036011424.1  ankyrin-3 isoform X11

      Conserved Domains (8) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:24062489
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      pfam05109
      Location:15511952
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    17. XM_006513133.4XP_006513196.1  ankyrin-3 isoform X12

      UniProtKB/TrEMBL
      S4R2K9
      Related
      ENSMUSP00000138686.2, ENSMUST00000182992.8
      Conserved Domains (8) summary
      smart00218
      Location:9901094
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:23332416
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      pfam05109
      Location:14721879
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13161445
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    18. XM_036155532.1XP_036011425.1  ankyrin-3 isoform X13

      Conserved Domains (7) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:15371620
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    19. XM_036155540.1XP_036011433.1  ankyrin-3 isoform X22

      Conserved Domains (7) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:15581641
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    20. XM_036155535.1XP_036011428.1  ankyrin-3 isoform X16

      Conserved Domains (7) summary
      smart00218
      Location:10121116
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14931576
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13381467
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    21. XM_036155533.1XP_036011426.1  ankyrin-3 isoform X14

      Conserved Domains (7) summary
      smart00218
      Location:10081112
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:15011584
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13341463
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    22. XM_036155534.1XP_036011427.1  ankyrin-3 isoform X15

      Conserved Domains (7) summary
      smart00218
      Location:10011105
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14941577
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13271456
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    23. XM_036155539.1XP_036011432.1  ankyrin-3 isoform X21

      Conserved Domains (7) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:15581641
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    24. XM_036155543.1XP_036011436.1  ankyrin-3 isoform X25

      Conserved Domains (7) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:15461629
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    25. XM_036155542.1XP_036011435.1  ankyrin-3 isoform X24

      Conserved Domains (7) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:15491632
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    26. XM_036155536.1XP_036011429.1  ankyrin-3 isoform X17

      Conserved Domains (7) summary
      smart00218
      Location:9901094
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14831566
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13161445
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    27. XM_036155537.1XP_036011430.1  ankyrin-3 isoform X18

      Conserved Domains (7) summary
      smart00218
      Location:9801084
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14731556
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13061435
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    28. XM_006513136.4XP_006513199.1  ankyrin-3 isoform X20

      Conserved Domains (7) summary
      smart00218
      Location:9691073
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14621545
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12951424
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    29. XM_036155541.1XP_036011434.1  ankyrin-3 isoform X23

      Conserved Domains (7) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:15491632
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    30. XM_036155544.1XP_036011437.1  ankyrin-3 isoform X26

      Conserved Domains (7) summary
      smart00218
      Location:10231160
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:15371620
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13821511
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    31. XM_036155545.1XP_036011438.1  ankyrin-3 isoform X27

      Conserved Domains (7) summary
      smart00218
      Location:10231127
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:15251608
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13491478
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    32. XM_036155546.1XP_036011439.1  ankyrin-3 isoform X28

      Conserved Domains (7) summary
      smart00218
      Location:10231127
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:15161599
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13491478
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    33. XM_036155548.1XP_036011441.1  ankyrin-3 isoform X30

      Conserved Domains (7) summary
      smart00218
      Location:10121116
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:15051588
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13381467
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    34. XM_036155550.1XP_036011443.1  ankyrin-3 isoform X33

      Conserved Domains (7) summary
      smart00218
      Location:9801084
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14821565
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13061435
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    35. XM_036155547.1XP_036011440.1  ankyrin-3 isoform X29

      Conserved Domains (7) summary
      smart00218
      Location:10121116
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:15051588
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13381467
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    36. XM_030244846.2XP_030100706.1  ankyrin-3 isoform X31

      Conserved Domains (7) summary
      smart00218
      Location:9901094
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14831566
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13161445
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    37. XM_036155551.1XP_036011444.1  ankyrin-3 isoform X35

      Conserved Domains (7) summary
      smart00218
      Location:9901094
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14711554
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13161445
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    38. XM_036155549.1XP_036011442.1  ankyrin-3 isoform X32

      Conserved Domains (7) summary
      smart00218
      Location:9801084
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14821565
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13061435
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    39. XM_036155556.1XP_036011449.1  ankyrin-3 isoform X41

      Conserved Domains (7) summary
      smart00218
      Location:9751079
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14561539
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13011430
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    40. XM_017313778.3XP_017169267.1  ankyrin-3 isoform X34

      Conserved Domains (7) summary
      smart00218
      Location:9821086
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14751558
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:369657
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:465496
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:763815
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:13081437
      UPA_2; UPA domain
      cl39094
      Location:551788
      Ank_2; Ankyrin repeats (3 copies)
    41. XM_006513138.4XP_006513201.1  ankyrin-3 isoform X40

      Conserved Domains (7) summary
      smart00218
      Location:9691073
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14621545
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:377665
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:473504
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:771823
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12951424
      UPA_2; UPA domain
      cl39094
      Location:559796
      Ank_2; Ankyrin repeats (3 copies)
    42. XM_036155555.1XP_036011448.1  ankyrin-3 isoform X39

      Conserved Domains (7) summary
      smart00218
      Location:9721076
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:14651548
      Death_ank3; Death domain of Ankyrin-3
      PHA03095
      Location:369657
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:465496
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:763815
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12981427
      UPA_2; UPA domain
      cl39094
      Location:551788
      Ank_2; Ankyrin repeats (3 copies)
    43. XM_006513139.5XP_006513202.1  ankyrin-3 isoform X43

      UniProtKB/TrEMBL
      S4R236
      Related
      ENSMUSP00000138337.2, ENSMUST00000182029.8
      Conserved Domains (3) summary
      smart00218
      Location:116220
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08803
      Location:609692
      Death_ank3; Death domain of Ankyrin-3
      pfam17809
      Location:442571
      UPA_2; UPA domain