Wmp WAVE homology in membrane protrusions [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Wmpprovided by MGI
Official Full Name: WAVE homology in membrane protrusionsprovided by MGI
Primary source: MGI:MGI:2685578
See related: Ensembl:ENSMUSG00000073006 AllianceGenome:MGI:2685578
Gene type: protein coding
RefSeq status: PREDICTED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm732; Whimp
Summary: Predicted to enable Arp2/3 complex binding activity and protein kinase A regulatory subunit binding activity. Predicted to be involved in actin cytoskeleton organization and positive regulation of Arp2/3 complex-mediated actin nucleation. Predicted to be part of SCAR complex. Predicted to be active in lamellipodium. [provided by Alliance of Genome Resources, Nov 2024]
Expression: Restricted expression toward testis adult (RPKM 4.0) See more
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Genomic context

Location:: X D; X 47.66 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (106989341..106992042, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (107945735..107948436, complement)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables Arp2/3 complex binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein kinase A regulatory subunit binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in actin cytoskeleton organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of Arp2/3 complex-mediated actin nucleation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of SCAR complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in lamellipodium	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: uncharacterized protein LOC213450

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.