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    ugt-15 UDP-glucuronosyltransferase [ Caenorhabditis elegans ]

    Gene ID: 183462, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ugt-15
    Official Full Name
    UDP-glucuronosyltransferase
    Primary source
    WormBase:WBGene00008097
    Locus tag
    CELE_C44H9.1
    See related
    AllianceGenome:WB:WBGene00008097
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Orthologous to human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ugt-15 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    8
    Sequence:
    Chromosome: V; NC_003283.11 (12827519..12830114)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene UDP-glucuronosyltransferase Neighboring gene UDP-glucuronosyltransferase Neighboring gene pseudo Neighboring gene DNA2/NAM7 helicase-like C-terminal domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Glucose or Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans. Ladage ML, et al. G3 (Bethesda), 2016 Oct 13. PMID 27507791, Free PMC Article
    2. UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences. Matoušková P, et al. Int J Parasitol Drugs Drug Resist, 2018 Dec. PMID 30293057, Free PMC Article
    3. CEST-2.2 overexpression alters lipid metabolism and extends longevity of mitochondrial mutants. Piazzesi A, et al. EMBO Rep, 2022 May 4. PMID 35297148, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glucuronosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    UDP-glucuronosyltransferase
    NP_506211.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      12827519..12830114
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073810.6 → NP_506211.1  UDP-glucuronosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506211.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18629
      Conserved Domains (2) summary
      pfam00201
      Location:19 → 506
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
      cl10013
      Location:252 → 493
      Glycosyltransferase_GTB_type; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...
    Nucleotide Protein
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