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    disease resistance protein (TIR-NBS-LRR class) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831634, updated on 18-Sep-2024

    Summary

    Official Full Name
    disease resistance protein (TIR-NBS-LRR class)
    Primary source
    TAIR:AT5G17680
    Locus tag
    AT5G17680
    See related
    Araport:AT5G17680
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MVA3.30; MVA3_30
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    Genomic context

    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (5822881..5827153)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene glycine/proline-rich protein Neighboring gene tRNA (guanine-N-7) methyltransferase Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene uncharacterized protein Neighboring gene MATE efflux family protein Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    disease resistance protein (TIR-NBS-LRR class)
    NP_197270.1
    • disease resistance protein (TIR-NBS-LRR class), putative; FUNCTIONS IN: transmembrane receptor activity, ATP binding; INVOLVED IN: signal transduction, defense response, apoptosis, innate immune response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Leucine-rich repeat, typical subtype (InterPro:IPR003591), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Disease resistance protein (InterPro:IPR000767), Toll-Interleukin receptor (InterPro:IPR000157); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) (TAIR:AT5G11250.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5822881..5827153
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343517.1NP_001331467.1  disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y4Z2, Q9FN83
    2. NM_121774.1NP_197270.1  disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197270.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y4Z2, F4KIC7
      Conserved Domains (7) summary
      COG4886
      Location:603915
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00116
      Location:604842
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:718740
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00931
      Location:191455
      NB-ARC; NB-ARC domain
      pfam01582
      Location:19177
      TIR; TIR domain
      pfam07725
      Location:603622
      LRR_3; Leucine Rich Repeat
      pfam13855
      Location:9571012
      LRR_8; Leucine rich repeat