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    mrpl-2 Large ribosomal subunit protein uL2 C-terminal domain-containing protein;Ribosomal_L2_C domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176903, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mrpl-2
    Official Full Name
    Large ribosomal subunit protein uL2 C-terminal domain-containing protein;Ribosomal_L2_C domain-containing protein
    Primary source
    WormBase:WBGene00018932
    Locus tag
    CELE_F56B3.8
    See related
    AllianceGenome:WB:WBGene00018932
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Orthologous to human MRPL2 (mitochondrial ribosomal protein L2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See mrpl-2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (773237..776655)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene EB domain-containing protein Neighboring gene pseudo Neighboring gene C2H2-type domain-containing protein Neighboring gene glucuronosyltransferase Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel gene-diet interaction promotes organismal lifespan and host protection during infection via the mitochondrial UPR. Amin MR, et al. PLoS Genet, 2020 Dec. PMID 33338044, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A novel gene-diet interaction promotes organismal lifespan and host protection during infection via the mitochondrial UPR.
      Title: A novel gene-diet interaction promotes organismal lifespan and host protection during infection via the mitochondrial UPR.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Large ribosomal subunit protein uL2 C-terminal domain-containing protein;Ribosomal_L2_C domain-containing protein
    NP_001368336.1
    • Confirmed by transcript evidence
    NP_499987.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      773237..776655
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067586.6 → NP_499987.2  Large ribosomal subunit protein uL2 C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499987.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45110
      Conserved Domains (1) summary
      COG0090
      Location:22 → 246
      RplB; Ribosomal protein L2 [Translation, ribosomal structure and biogenesis]

    2. NM_001380018.1 → NP_001368336.1  Ribosomal_L2_C domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PFC3
    Nucleotide Protein
    Heading Accession and Version

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