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    sydn-1 Synaptic defective enhancer 1 [ Caenorhabditis elegans ]

    Gene ID: 189773, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sydn-1
    Official Full Name
    Synaptic defective enhancer 1
    Primary source
    WormBase:WBGene00021473
    Locus tag
    CELE_Y39G10AR.17
    See related
    AllianceGenome:WB:WBGene00021473
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mRNA processing. Located in nuclear speck. Is expressed in germ cell; hypodermis; and neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sydn-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (2377089..2381851, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene non-specific serine/threonine protein kinase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Histone-lysine N-methyltransferase, H3 lysine-79 specific Neighboring gene Protein zwilch homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Negative regulation of Caenorhabditis elegans epidermal damage responses by death-associated protein kinase. Tong A, et al. Proc Natl Acad Sci U S A, 2009 Feb 3. PMID 19164535, Free PMC Article
    2. Context-dependent modulation of Pol II CTD phosphatase SSUP-72 regulates alternative polyadenylation in neuronal development. Chen F, et al. Genes Dev, 2015 Nov 15. PMID 26588990, Free PMC Article
    3. Tissue-specific regulation of alternative polyadenylation represses expression of a neuronal ankyrin isoform in C. elegans epidermal development. Chen F, et al. Development, 2017 Feb 15. PMID 28087624, Free PMC Article
    4. Widespread genetic incompatibility in C. elegans maintained by balancing selection. Seidel HS, et al. Science, 2008 Feb 1. PMID 18187622, Free PMC Article
    5. Nuclear pre-mRNA 3'-end processing regulates synapse and axon development in C. elegans. Van Epps H, et al. Development, 2010 Jul. PMID 20530551, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. loss of sydn-1 blocks ectopic expression of neuronal ankyrin and suppresses epidermal morphology defects of dapk-1; effects of sydn-1 are mediated by ssup-72 autonomously in the epidermis
      Title: Tissue-specific regulation of alternative polyadenylation represses expression of a neuronal ankyrin isoform in C. elegans epidermal development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nuclear speck IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Synaptic defective enhancer 1
    NP_001367776.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      2377089..2381851 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001381388.1 → NP_001367776.1  Synaptic defective enhancer 1 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95XQ1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95XQ1.4

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