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    grsf1 G-rich RNA sequence binding factor 1 [ Danio rerio (zebrafish) ]

    Gene ID: 563249, updated on 9-Dec-2024

    Summary

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    Official Symbol
    grsf1provided by ZNC
    Official Full Name
    G-rich RNA sequence binding factor 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060825-196
    See related
    Ensembl:ENSDARG00000053021 AllianceGenome:ZFIN:ZDB-GENE-060825-196
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb62c04; zgc:153305
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Orthologous to human GRSF1 (G-rich RNA sequence binding factor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See grsf1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (42943972..42950883, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (42343819..42350801, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101886481 Neighboring gene chemokine (C-X-C motif) ligand 20 Neighboring gene RUN and FYVE domain containing 3 Neighboring gene MOB kinase activator 1Ba Neighboring gene aquaporin 3a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Revealing genes associated with vitellogenesis in the liver of the zebrafish (Danio rerio) by transcriptome profiling. Levi L, et al. BMC Genomics, 2009 Mar 31. PMID 19335895, Free PMC Article
    2. Shutdown corner, a large deletion mutant isolated from a haploid mutagenesis screen in zebrafish. Casey MA, et al. G3 (Bethesda), 2022 Mar 4. PMID 35079792, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC153305

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    G-rich sequence factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045852.1 → NP_001039317.1  G-rich sequence factor 1

      See identical proteins and their annotated locations for NP_001039317.1

      Status: PROVISIONAL

      Source sequence(s)
      BC122226
      UniProtKB/TrEMBL
      Q0P482
      Conserved Domains (4) summary
      COG0724
      Location:28 → 266
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12505
      Location:133 → 207
      RRM2_GRSF1; RNA recognition motif 2 in G-rich sequence factor 1 (GRSF-1) and similar proteins
      cd12730
      Location:36 → 114
      RRM1_GRSF1; RNA recognition motif 1 in G-rich sequence factor 1 (GRSF-1) and similar proteins
      cl17169
      Location:246 → 301
      RRM_SF; RNA recognition motif (RRM) superfamily

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      42943972..42950883 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005165334.3 → XP_005165391.1  G-rich sequence factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BCT6, F8W4V6
      Related
      ENSDARP00000124123.1, ENSDART00000149868.3
      Conserved Domains (4) summary
      COG0724
      Location:106 → 403
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12505
      Location:211 → 285
      RRM2_GRSF1; RNA recognition motif 2 in G-rich sequence factor 1 (GRSF-1) and similar proteins
      cd12730
      Location:114 → 192
      RRM1_GRSF1; RNA recognition motif 1 in G-rich sequence factor 1 (GRSF-1) and similar proteins
      cl17169
      Location:324 → 396
      RRM_SF; RNA recognition motif (RRM) superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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