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    Zfp787 zinc finger protein 787 [ Mus musculus (house mouse) ]

    Gene ID: 67109, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zfp787provided by MGI
    Official Full Name
    zinc finger protein 787provided by MGI
    Primary source
    MGI:MGI:1914359
    See related
    Ensembl:ENSMUSG00000046792 AllianceGenome:MGI:1914359
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Znf787; 2210018M03Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; male reproductive system; and urinary system. Orthologous to human ZNF787 (zinc finger protein 787). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 27.5), adrenal adult (RPKM 22.9) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfp787 in Genome Data Viewer
    Location:
    7 A1; 7 3.55 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (6134488..6162382, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (6131489..6159380, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene NLR family, pyrin domain containing 4C Neighboring gene predicted gene, 18758 Neighboring gene STARR-positive B cell enhancer ABC_E9284 Neighboring gene predicted gene, 36371 Neighboring gene STARR-positive B cell enhancer ABC_E4893 Neighboring gene zinc finger protein 444 Neighboring gene STARR-seq mESC enhancer starr_17966 Neighboring gene galanin-like peptide

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Comprehensive interactome of Otx2 in the adult mouse neural retina. Fant B, et al. Genesis, 2015 Nov. PMID 26426291
    2. Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain. Lee Y, et al. Biochem Biophys Res Commun, 2020 Aug 13. PMID 32560809
    3. A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Wiese CB, et al. Front Neurosci, 2012. PMID 22988430, Free PMC Article
    4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    5. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific double-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 787

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013012.2 → NP_001013030.1  zinc finger protein 787 isoform a

      See identical proteins and their annotated locations for NP_001013030.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2), as well as variant 1, encodes the longer isoform (a).
      Source sequence(s)
      AC026949
      Consensus CDS
      CCDS20769.1
      UniProtKB/Swiss-Prot
      B9EHE2, Q8BIF9
      Related
      ENSMUSP00000092468.2, ENSMUST00000094870.3
      Conserved Domains (3) summary
      COG5048
      Location:93 → 200
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:68 → 88
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:66 → 88
      zf-C2H2; Zinc finger, C2H2 type

    2. NM_001379298.1 → NP_001366227.1  zinc finger protein 787 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4), as well as variant 3, encodes isoform b.
      Source sequence(s)
      AC026949
      Conserved Domains (3) summary
      COG5048
      Location:62 → 169
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:37 → 57
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:35 → 57
      zf-C2H2; Zinc finger, C2H2 type

    3. NM_001379299.1 → NP_001366228.1  zinc finger protein 787 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3), as well as variant 4, encodes isoform b.
      Source sequence(s)
      AC026949
      Conserved Domains (3) summary
      COG5048
      Location:62 → 169
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:37 → 57
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:35 → 57
      zf-C2H2; Zinc finger, C2H2 type

    4. NM_001379300.1 → NP_001366229.1  zinc finger protein 787 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1), as well as variant 2, encodes the longer isoform (a).
      Source sequence(s)
      AC026949
      UniProtKB/Swiss-Prot
      B9EHE2, Q8BIF9
      Conserved Domains (3) summary
      COG5048
      Location:93 → 200
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:68 → 88
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:66 → 88
      zf-C2H2; Zinc finger, C2H2 type

    RNA

    1. NR_166603.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC026949

    2. NR_166604.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC026949

    3. NR_166605.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC026949

    4. NR_166606.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC026949
      Related
      ENSMUST00000207628.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      6134488..6162382 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006540313.5 → XP_006540376.1  zinc finger protein 787 isoform X1

      See identical proteins and their annotated locations for XP_006540376.1

      UniProtKB/Swiss-Prot
      B9EHE2, Q8BIF9
      Conserved Domains (3) summary
      COG5048
      Location:93 → 200
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:68 → 88
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:66 → 88
      zf-C2H2; Zinc finger, C2H2 type
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BIF9.3 GenPept UniProtKB/Swiss-Prot:Q8BIF9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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