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    SEMA7A semaphorin 7A (JohnMiltonHagen blood group) [ Nomascus leucogenys (northern white-cheeked gibbon) ]

    Gene ID: 100582496, updated on 8-Mar-2024

    Summary

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    Gene symbol
    SEMA7A
    Gene description
    semaphorin 7A (JohnMiltonHagen blood group)
    See related
    EnsemblRapid:ENSNLEG00000014432
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Nomascus leucogenys
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
    Orthologs
    human mouse all
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    Genomic context

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    See SEMA7A in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current Asia_NLE_v1 (GCF_006542625.1) 6 NC_044386.1 (93803807..93831789, complement)
    102 previous assembly Nleu_3.0 (GCF_000146795.2) 6 NC_019821.1 (93960832..93990550, complement)

    Chromosome 6 - NC_044386.1Genomic Context describing neighboring genes Neighboring gene cholesterol side-chain cleavage enzyme, mitochondrial Neighboring gene peptidyl-prolyl cis-trans isomerase A pseudogene Neighboring gene uncharacterized LOC115835401 Neighboring gene ubiquitin like 7 Neighboring gene small nucleolar RNA SNORD77

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chemorepellent activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables semaphorin receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of axon extension involved in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neural crest cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of ERK1 and ERK2 cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of axon extension IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of macrophage cytokine production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in semaphorin-plexin signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    semaphorin-7A
    Names
    semaphorin 7A (John Milton Hagen blood group)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Asia_NLE_v1 Primary Assembly

    Genomic

    1. NC_044386.1 Reference Asia_NLE_v1 Primary Assembly

      Range
      93803807..93831789 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030814750.1 → XP_030670610.1  semaphorin-7A isoform X2

      UniProtKB/TrEMBL
      A0A2I3HIG9
      Conserved Domains (3) summary
      smart00423
      Location:328 → 377
      PSI; domain found in Plexins, Semaphorins and Integrins
      cl11960
      Location:384 → 454
      Ig; Immunoglobulin domain
      cl15693
      Location:1 → 326
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    2. XM_030814751.1 → XP_030670611.1  semaphorin-7A isoform X3

      UniProtKB/TrEMBL
      G1RWI4

    3. XM_003267207.3 → XP_003267255.2  semaphorin-7A isoform X1

      UniProtKB/TrEMBL
      G1RWI4
      Related
      ENSNLEP00000017611.2, ENSNLET00000018489.4
      Conserved Domains (2) summary
      cd11243
      Location:70 → 489
      Sema_7A; The Sema domain, a protein interacting module, of semaphorin 7A (Sema7A, also called CD108)
      smart00423
      Location:491 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins

    4. XM_012507444.2 → XP_012362898.1  semaphorin-7A isoform X2

      UniProtKB/TrEMBL
      A0A2I3HIG9
      Conserved Domains (3) summary
      smart00423
      Location:328 → 377
      PSI; domain found in Plexins, Semaphorins and Integrins
      cl11960
      Location:384 → 454
      Ig; Immunoglobulin domain
      cl15693
      Location:1 → 326
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins
    Nucleotide Protein
    Heading Accession and Version

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