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    Mroh2a maestro heat-like repeat family member 2A [ Mus musculus (house mouse) ]

    Gene ID: 100040766, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mroh2aprovided by MGI
    Official Full Name
    maestro heat-like repeat family member 2Aprovided by MGI
    Primary source
    MGI:MGI:3705228
    See related
    Ensembl:ENSMUSG00000079429 AllianceGenome:MGI:3705228
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Heatr7b1
    Summary
    Predicted to be active in cytoplasm. Orthologous to human MROH2A (maestro heat like repeat family member 2A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 40.8), genital fat pad adult (RPKM 3.9) and 2 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Mroh2a in Genome Data Viewer
    Location:
    1 D; 1 44.55 cM
    Exon count:
    47
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (88154713..88190011)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (88226991..88262289)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene UDP glycosyltransferase 1 family, polypeptide A10 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A9 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A8 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A7C Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A6B Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A6A Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A5 Neighboring gene STARR-positive B cell enhancer mm9_chr1:90112870-90113171 Neighboring gene STARR-positive B cell enhancer mm9_chr1:90113610-90113910 Neighboring gene STARR-seq mESC enhancer starr_01629 Neighboring gene STARR-positive B cell enhancer mm9_chr1:90118277-90118578 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A2 Neighboring gene DnaJ heat shock protein family (Hsp40) member B3 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A1 Neighboring gene STARR-positive B cell enhancer mm9_chr1:90185502-90185802 Neighboring gene STARR-positive B cell enhancer mm9_chr1:90186563-90186863 Neighboring gene Holliday junction recognition protein Neighboring gene STARR-positive B cell enhancer mm9_chr1:90195708-90196009 Neighboring gene transient receptor potential cation channel, subfamily M, member 8 Neighboring gene STARR-seq mESC enhancer starr_01631 Neighboring gene secreted phosphoprotein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J. Timmermans S, et al. JCI Insight, 2018 Jul 12. PMID 29997285, Free PMC Article
    2. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
    3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    maestro heat-like repeat-containing protein family member 2A
    Names
    HEAT repeat containing 7B1
    HEAT repeat-containing protein 7B1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001281466.1 → NP_001268395.1  maestro heat-like repeat-containing protein family member 2A

      Status: VALIDATED

      Source sequence(s)
      AC087780
      Consensus CDS
      CCDS69921.1
      UniProtKB/Swiss-Prot
      D3Z750
      UniProtKB/TrEMBL
      F5H8M8
      Related
      ENSMUSP00000108755.2, ENSMUST00000113130.8

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      88154713..88190011
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006529044.3 → XP_006529107.1  maestro heat-like repeat-containing protein family member 2A isoform X4

      UniProtKB/Swiss-Prot
      D3Z750

    2. XM_006529040.3 → XP_006529103.1  maestro heat-like repeat-containing protein family member 2A isoform X1

      See identical proteins and their annotated locations for XP_006529103.1

      UniProtKB/Swiss-Prot
      D3Z750

    3. XM_006529042.3 → XP_006529105.1  maestro heat-like repeat-containing protein family member 2A isoform X2

      UniProtKB/Swiss-Prot
      D3Z750

    4. XM_006529043.2 → XP_006529106.1  maestro heat-like repeat-containing protein family member 2A isoform X3

      UniProtKB/Swiss-Prot
      D3Z750

    5. XM_006529041.2 → XP_006529104.1  maestro heat-like repeat-containing protein family member 2A isoform X1

      See identical proteins and their annotated locations for XP_006529104.1

      UniProtKB/Swiss-Prot
      D3Z750

    6. XM_006529048.4 → XP_006529111.1  maestro heat-like repeat-containing protein family member 2A isoform X7

      See identical proteins and their annotated locations for XP_006529111.1

    7. XM_006529049.4 → XP_006529112.1  maestro heat-like repeat-containing protein family member 2A isoform X7

      See identical proteins and their annotated locations for XP_006529112.1

    8. XM_006529045.2 → XP_006529108.1  maestro heat-like repeat-containing protein family member 2A isoform X5

    9. XM_006529046.3 → XP_006529109.1  maestro heat-like repeat-containing protein family member 2A isoform X6

    RNA

    1. XR_387134.4 RNA Sequence

    2. XR_003946480.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001177364.1: Suppressed sequence

      Description
      NM_001177364.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    D3Z750.2 GenPept UniProtKB/Swiss-Prot:D3Z750

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