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    PIP2;5 plasma membrane intrinsic protein 2;5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824647, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PIP2;5
    Official Full Name
    plasma membrane intrinsic protein 2;5
    Primary source
    TAIR:AT3G54820
    Locus tag
    AT3G54820
    See related
    Araport:AT3G54820
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    PIP2D; plasma membrane intrinsic protein 2;5; PLASMA MEMBRANE INTRINSIC PROTEIN 2D
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    Genomic context

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    See PIP2;5 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (20301759..20304309)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Pleckstrin homology (PH) and lipid-binding START domains-containing protein Neighboring gene Plant-specific GATA-type zinc finger transcription factor family protein Neighboring gene pseudo Neighboring gene Zim17-type zinc finger protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plasma Membrane Aquaporin Members PIPs Act in Concert to Regulate Cold Acclimation and Freezing Tolerance Responses in Arabidopsis thaliana. Rahman A, et al. Plant Cell Physiol, 2020 Apr 1. PMID 31999343
    2. Overexpression of PIP2;5 aquaporin alleviates effects of low root temperature on cell hydraulic conductivity and growth in Arabidopsis. Lee SH, et al. Plant Physiol, 2012 May. PMID 22434042, Free PMC Article
    3. The complete set of genes encoding major intrinsic proteins in Arabidopsis provides a framework for a new nomenclature for major intrinsic proteins in plants. Johanson U, et al. Plant Physiol, 2001 Aug. PMID 11500536, Free PMC Article
    4. A membrane protein/signaling protein interaction network for Arabidopsis version AMPv2. Lalonde S, et al. Front Physiol, 2010. PMID 21423366, Free PMC Article
    5. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Plasma Membrane Aquaporin Members PIPs Act in Concert to Regulate Cold Acclimation and Freezing Tolerance Responses in Arabidopsis thaliana.
      Title: Plasma Membrane Aquaporin Members PIPs Act in Concert to Regulate Cold Acclimation and Freezing Tolerance Responses in Arabidopsis thaliana.
    2. Low root temperature had no effect on growth in plants overexpressing PIP2;5.
      Title: Overexpression of PIP2;5 aquaporin alleviates effects of low root temperature on cell hydraulic conductivity and growth in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_115339.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables water channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within water transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    plasma membrane intrinsic protein 2;5
    NP_191042.1
    • plasma membrane intrinsic protein 2;5 (PIP2;5); FUNCTIONS IN: water channel activity; INVOLVED IN: transport, transmembrane transport; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: plasma membrane intrinsic protein 2 (TAIR:AT2G37170.1); Has 10866 Blast hits to 10851 proteins in 2236 species: Archae - 80; Bacteria - 5189; Metazoa - 1483; Fungi - 451; Plants - 2536; Viruses - 2; Other Eukaryotes - 1125 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      20301759..20304309
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115339.3 → NP_191042.1  plasma membrane intrinsic protein 2;5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191042.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SV31
      UniProtKB/TrEMBL
      A0A5S9XKZ5, A0A654FFU4
      Conserved Domains (1) summary
      pfam00230
      Location:30 → 265
      MIP; Major intrinsic protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SV31.1

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