SCL3 scarecrow-like 3 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: SCL3
Official Full Name: scarecrow-like 3
Primary source: TAIR:AT1G50420
Locus tag: AT1G50420
See related: Araport:AT1G50420
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F11F12.22; F11F12_22; scarecrow-like 3; SCARECROW-LIKE 3; SCL-3
Summary: Encodes a scarecrow-like protein (SCL3) Putative transcription factors interacting with the gene product of VHA-B1 (vacuolar ATPase subunit B1; as shown through yeast two-hybrid assay).
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Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Gene Regulation via the Combination of Transcription Factors in the INDETERMINATE DOMAIN and GRAS Families.
Title: Gene Regulation via the Combination of Transcription Factors in the INDETERMINATE DOMAIN and GRAS Families.
SCARECROW-LIKE3 regulates the transcription of gibberellin-related genes by acting as a transcriptional co-repressor of GAI-ASSOCIATED FACTOR1.
Title: SCARECROW-LIKE3 regulates the transcription of gibberellin-related genes by acting as a transcriptional co-repressor of GAI-ASSOCIATED FACTOR1.
Data indicate that SEUSS (SEU) gene has distinct genetic interactions with SHORT-ROOT (SHR), SCARECROW (SCR), and SCARECROW-LIKE3 (SCL3) genes.
Title: SEUSS Integrates Gibberellin Signaling with Transcriptional Inputs from the SHR-SCR-SCL3 Module to Regulate Middle Cortex Formation in the Arabidopsis Root.
The balance of the DELLAs and SCL3 protein levels (both are GRAS proteins) regulates downstream gene expression through IDDs binding to DNA. Review.
Title: DELLA and SCL3 balance gibberellin feedback regulation by utilizing INDETERMINATE DOMAIN proteins as transcriptional scaffolds.
A coregulator exchange system between DELLA (as coactivator) and SCL3 (as corepressor) regulates the expression of SCL3.
Title: DELLA protein functions as a transcriptional activator through the DNA binding of the indeterminate domain family proteins.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_103925.6

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within response to gibberellin	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

NP_175459.1

scarecrow-like 3 (SCL3); CONTAINS InterPro DOMAIN/s: Transcription factor GRAS (InterPro:IPR005202); BEST Arabidopsis thaliana protein match is: SCARECROW-like 21 (TAIR:AT2G04890.1); Has 3106 Blast hits to 2488 proteins in 309 species: Archae - 0; Bacteria - 6; Metazoa - 0; Fungi - 0; Plants - 3100; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).