DHDPS2 dihydrodipicolinate synthase [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: DHDPS2
Official Full Name: dihydrodipicolinate synthase
Primary source: TAIR:AT2G45440
Locus tag: AT2G45440
See related: Araport:AT2G45440
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: dihydrodipicolinate synthase; dihydrodipicolinate synthase 2; F4L23.5
Summary: Encodes a protein that likely has dihydropicolinate synthase activity based on its mutant phenotype of decreased lysine levels and increased aspartate levels. The mutant also has increased levels of threonine. The enzyme is predicted to localize to the chloroplast.
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Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_130106.3

Function	Evidence Code	Pubs
enables 4-hydroxy-tetrahydrodipicolinate synthase activity	IDA Inferred from Direct Assay more info	PubMed
enables 4-hydroxy-tetrahydrodipicolinate synthase activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in lysine biosynthetic process via diaminopimelate	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info

NP_182068.1

dihydrodipicolinate synthase (DHDPS2); FUNCTIONS IN: dihydrodipicolinate synthase activity; INVOLVED IN: lysine biosynthetic process via diaminopimelate, metabolic process, diaminopimelate biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Dihydrodipicolinate synthase subfamily (InterPro:IPR005263), Dihydrodipicolinate synthetase (InterPro:IPR002220), Dihydrodipicolinate synthetase, active site (InterPro:IPR020625), Dihydrodipicolinate synthetase, conserved site (InterPro:IPR020624); BEST Arabidopsis thaliana protein match is: dihydrodipicolinate synthase 1 (TAIR:AT3G60880.2); Has 13334 Blast hits to 13334 proteins in 2656 species: Archae - 353; Bacteria - 9459; Metazoa - 101; Fungi - 305; Plants - 96; Viruses - 0; Other Eukaryotes - 3020 (source: NCBI BLink).