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    TTN10 GINS complex protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838490, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TTN10
    Official Full Name
    GINS complex protein
    Primary source
    TAIR:AT1G19080
    Locus tag
    AT1G19080
    See related
    Araport:AT1G19080
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F14D16.33; Partner of SLD5 3; PSF3; TITAN 10
    Summary
    This gene is predicted to encode a PSF3 component of the GINS complex. This complex has been implicated in the initiation of DNA replication in Xenopus. Mutations in this gene cause defects in embryo development.
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    Genomic context

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    See TTN10 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (6584241..6586517)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene response regulator 7 Neighboring gene hypothetical protein (DUF626) Neighboring gene F-box family protein Neighboring gene uncharacterized protein Neighboring gene receptor-like serine/threonine kinase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide analysis of the core DNA replication machinery in the higher plants Arabidopsis and rice. Shultz RW, et al. Plant Physiol, 2007 Aug. PMID 17556508, Free PMC Article
    2. Identification of genes required for embryo development in Arabidopsis. Tzafrir I, et al. Plant Physiol, 2004 Jul. PMID 15266054, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_001198102.1
    NM_101766.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA-templated DNA replication ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of GINS complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    GINS complex protein
    NP_001185031.1
    • TITAN 10 (TTN10); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: DNA-dependent DNA replication, embryo development ending in seed dormancy; LOCATED IN: GINS complex; EXPRESSED IN: pollen tube; CONTAINS InterPro DOMAIN/s: GINS complex, subunit Psf3 (InterPro:IPR010492), GINS complex (InterPro:IPR021151); BEST Arabidopsis thaliana protein match is: GINS complex protein (TAIR:AT3G55490.1).
    NP_173342.2
    • TITAN 10 (TTN10); CONTAINS InterPro DOMAIN/s: GINS complex, subunit Psf3 (InterPro:IPR010492), GINS complex (InterPro:IPR021151); BEST Arabidopsis thaliana protein match is: GINS complex protein (TAIR:AT3G55490.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6584241..6586517
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001198102.1 → NP_001185031.1  GINS complex protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185031.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VCB9, A0A384LKD0, A0MDR5, Q6NNH6
      Conserved Domains (2) summary
      cd11713
      Location:61 → 167
      GINS_A_psf3; Alpha-helical domain of GINS complex protein Psf3 (partner of Sld5 3)
      cd21693
      Location:4 → 66
      GINS_B_Psf3; beta-strand (B) domain of GINS complex protein Psf3

    2. NM_101766.3 → NP_173342.2  GINS complex protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173342.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VCB9, A0A384LKD0, A0MDR5, Q6NNH6
      Conserved Domains (2) summary
      cd11713
      Location:61 → 167
      GINS_A_psf3; Alpha-helical domain of GINS complex protein Psf3 (partner of Sld5 3)
      cd21693
      Location:4 → 66
      GINS_B_Psf3; beta-strand (B) domain of GINS complex protein Psf3
    Nucleotide Protein
    Heading Accession and Version

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