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    fd3F forkhead domain 3F [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31336, updated on 9-Dec-2024

    Summary

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    Official Symbol
    fd3Fprovided by FlyBase
    Official Full Name
    forkhead domain 3Fprovided by FlyBase
    Primary source
    FLYBASE:FBgn0264954
    Locus tag
    Dmel_CG44123
    See related
    AllianceGenome:FB:FBgn0264954
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12632; CG15238; CG18771; CG32779; CG44123; Dmel\CG44123; fd3f; Fd3F; FoxT
    Old locus tag
    Dmel_CG12632; Dmel_CG32779
    Summary
    Enables transcription cis-regulatory region binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Is expressed in several structures, including chordotonal neurons; chordotonal organ; and chordotonal organ precursor cell. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See fd3F in Genome Data Viewer
    Location:
    3F2-3F2; 1-5 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (3802316..3811040)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (3696349..3705073)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44118 Neighboring gene pseudo Neighboring gene Hsc/Hsp70-interacting protein Neighboring gene transfer RNA:Glutamine-CTG 2-1 Neighboring gene echinus Neighboring gene transfer RNA:Proline-CGG 3-1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Drosophila model for Meniere's disease: Dystrobrevin is required for support cell function in hearing and proprioception. Requena T, et al. Front Cell Dev Biol, 2022. PMID 36438562, Free PMC Article
    2. Duplicate gene evolution toward multiple fates at the Drosophila melanogaster HIP/HIP-Replacement locus. Hogan CC, et al. J Mol Evol, 2009 Apr. PMID 19333534
    3. Mutations in ZMYND10, a gene essential for proper axonemal assembly of inner and outer dynein arms in humans and flies, cause primary ciliary dyskinesia. Moore DJ, et al. Am J Hum Genet, 2013 Aug 8. PMID 23891471, Free PMC Article
    4. HEATR2 plays a conserved role in assembly of the ciliary motile apparatus. Diggle CP, et al. PLoS Genet, 2014 Sep. PMID 25232951, Free PMC Article
    5. Survey of forkhead domain encoding genes in the Drosophila genome: Classification and embryonic expression patterns. Lee HH, et al. Dev Dyn, 2004 Feb. PMID 14745961

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: 3803907-3804045 mobile_element_type = transposon:INE-1{}1942

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription cis-regulatory region binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anatomical structure morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    forkhead domain 3F
    Names
    CG44123-PC
    CG44123-PD
    fd3F-PC
    fd3F-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      3802316..3811040
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001370027.1 → NP_001356931.1  forkhead domain 3F, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4D6K5G3
      Conserved Domains (1) summary
      pfam00250
      Location:401 → 473
      Forkhead; Forkhead domain

    2. NM_166991.3 → NP_726889.3  forkhead domain 3F, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726889.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W4Q1
      Conserved Domains (1) summary
      pfam00250
      Location:401 → 473
      Forkhead; Forkhead domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A4D6K5G3 A0A4D6K5G3
    Q8T9W8 Q8T9W8
    Q9W4Q1 Q9W4Q1

    Gene LinkOut

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