ARHGAP21 Rho GTPase activating protein 21 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: ARHGAP21provided by VGNC
Official Full Name: Rho GTPase activating protein 21provided by VGNC
Primary source: VGNC:VGNC:100296
See related: Ensembl:ENSMMUG00000016123
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 30

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	9	NC_041762.1 (25612797..25747169, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	9	NC_027901.1 (24753062..24886896, complement)

Chromosome 9 - NC_041762.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

SHGC-146218 (e-PCR)
- UniSTS:172567

RH65067 (e-PCR)
- UniSTS:83611

RH66951 (e-PCR)
- UniSTS:88505

RH37461 (e-PCR)
- UniSTS:49146

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Golgi localization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: rho GTPase-activating protein 21

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001261285.1 → NP_001248214.1 rho GTPase-activating protein 21

See identical proteins and their annotated locations for NP_001248214.1

Status: PROVISIONAL

Source sequence(s)

JV047765

UniProtKB/TrEMBL

F7FQM2, G7N1R3, I0FTR0

Related

ENSMMUP00000021210.4, ENSMMUT00000022672.4

Conserved Domains (3) summary

cd00992
Location:48 → 155

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd04395
Location:1134 → 1329

RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...

cd01253
Location:923 → 1032

PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041762.1 Reference Mmul_10 Primary Assembly

Range

25612797..25747169 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028853423.1 → XP_028709256.1 rho GTPase-activating protein 21 isoform X3

UniProtKB/TrEMBL

G7N1R3

Conserved Domains (3) summary

cd00992
Location:48 → 155

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd04395
Location:1144 → 1339

RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...

cd01253
Location:933 → 1042

PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain
XM_028853421.1 → XP_028709254.1 rho GTPase-activating protein 21 isoform X1

UniProtKB/TrEMBL

A0A1D5RL14, G7N1R3

Conserved Domains (3) summary

cd00992
Location:48 → 155

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd04395
Location:1178 → 1373

RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...

cd01253
Location:967 → 1076

PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain
XM_028853426.1 → XP_028709259.1 rho GTPase-activating protein 21 isoform X4

UniProtKB/TrEMBL

F7FQM2, G7N1R3, I0FTR0

Conserved Domains (3) summary

cd00992
Location:48 → 155

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd04395
Location:1134 → 1329

RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...

cd01253
Location:923 → 1032

PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain
XM_028853424.1 → XP_028709257.1 rho GTPase-activating protein 21 isoform X3

UniProtKB/TrEMBL

G7N1R3

Conserved Domains (3) summary

cd00992
Location:48 → 155

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd04395
Location:1144 → 1339

RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...

cd01253
Location:933 → 1042

PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain
XM_028853420.1 → XP_028709253.1 rho GTPase-activating protein 21 isoform X1

UniProtKB/TrEMBL

A0A1D5RL14, G7N1R3

Related

ENSMMUP00000061009.1, ENSMMUT00000075751.2

Conserved Domains (3) summary

cd00992
Location:48 → 155

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd04395
Location:1178 → 1373

RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...

cd01253
Location:967 → 1076

PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain
XM_028853425.1 → XP_028709258.1 rho GTPase-activating protein 21 isoform X4

UniProtKB/TrEMBL

F7FQM2, G7N1R3, I0FTR0

Conserved Domains (3) summary

cd00992
Location:48 → 155

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd04395
Location:1134 → 1329

RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...

cd01253
Location:923 → 1032

PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain
XM_028853419.1 → XP_028709252.1 rho GTPase-activating protein 21 isoform X1

UniProtKB/TrEMBL

A0A1D5RL14, G7N1R3

Conserved Domains (3) summary

cd00992
Location:48 → 155

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd04395
Location:1178 → 1373

RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...

cd01253
Location:967 → 1076

PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain
XM_028853422.1 → XP_028709255.1 rho GTPase-activating protein 21 isoform X2

UniProtKB/TrEMBL

G7N1R3

Conserved Domains (3) summary

cd00992
Location:48 → 155

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd04395
Location:1168 → 1363

RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...

cd01253
Location:957 → 1066

PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain