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    RIPK2 receptor interacting serine/threonine kinase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695567, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RIPK2provided by VGNC
    Official Full Name
    receptor interacting serine/threonine kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:76696
    See related
    Ensembl:ENSMMUG00000020725
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See RIPK2 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (90153083..90190754)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (88262021..88298664)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106999848 Neighboring gene uncharacterized LOC114680291 Neighboring gene uncharacterized LOC106999849 Neighboring gene U6 spliceosomal RNA Neighboring gene oxidative stress induced growth inhibitor family member 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables JUN kinase kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    receptor-interacting serine/threonine-protein kinase 2
    XP_001084687.1
    XP_015001159.1
    XP_015001160.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      90153083..90190754
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001084687.4 → XP_001084687.1  receptor-interacting serine/threonine-protein kinase 2 isoform X1

      See identical proteins and their annotated locations for XP_001084687.1

      UniProtKB/TrEMBL
      F6Q6C2, G7MZQ5
      Related
      ENSMMUP00000032057.2, ENSMMUT00000038968.3
      Conserved Domains (3) summary
      cd08786
      Location:438 → 524
      CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
      smart00221
      Location:21 → 290
      STYKc; Protein kinase; unclassified specificity
      cl21453
      Location:20 → 303
      PKc_like; Protein Kinases, catalytic domain

    2. XM_015145673.2 → XP_015001159.1  receptor-interacting serine/threonine-protein kinase 2 isoform X2

      UniProtKB/TrEMBL
      G7MZQ5
      Conserved Domains (3) summary
      cd08786
      Location:408 → 494
      CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
      smart00221
      Location:21 → 290
      STYKc; Protein kinase; unclassified specificity
      cl21453
      Location:20 → 303
      PKc_like; Protein Kinases, catalytic domain

    3. XM_015145674.2 → XP_015001160.1  receptor-interacting serine/threonine-protein kinase 2 isoform X3

      UniProtKB/TrEMBL
      H9F423
      Conserved Domains (2) summary
      cd08786
      Location:341 → 427
      CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
      cl21453
      Location:1 → 206
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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