U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701400, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ARAP3provided by VGNC
    Official Full Name
    ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3provided by VGNC
    Primary source
    VGNC:VGNC:69893
    See related
    Ensembl:ENSMMUG00000000465
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ARAP3 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (139035075..139063578, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (139428892..139457820, complement)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene histone deacetylase 3 Neighboring gene FCH and double SH3 domains 1 Neighboring gene RELT like 2 Neighboring gene uncharacterized LOC106998972 Neighboring gene protocadherin 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-3,4,5-trisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in ruffle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      139035075..139063578 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015141089.2 → XP_014996575.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X4

      UniProtKB/TrEMBL
      G7MVC0
      Conserved Domains (9) summary
      cd09490
      Location:4 → 66
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      smart00454
      Location:12 → 64
      SAM; Sterile alpha motif
      cd04385
      Location:853 → 1028
      RhoGAP_ARAP; RhoGAP_ARAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ...
      cd13253
      Location:231 → 323
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:340 → 421
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      pfam00169
      Location:230 → 321
      PH; PH domain
      pfam00788
      Location:1061 → 1153
      RA; Ras association (RalGDS/AF-6) domain
      pfam01412
      Location:432 → 548
      ArfGap; Putative GTPase activating protein for Arf
      cl17171
      Location:1156 → 1275
      PH-like; Pleckstrin homology-like domain

    2. XM_015141088.2 → XP_014996574.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A1D5RDA8, G7MVC0
      Related
      ENSMMUP00000058301.2, ENSMMUT00000060800.2
      Conserved Domains (9) summary
      cd09490
      Location:4 → 66
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      smart00454
      Location:12 → 64
      SAM; Sterile alpha motif
      cd04385
      Location:911 → 1086
      RhoGAP_ARAP; RhoGAP_ARAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ...
      cd13253
      Location:289 → 381
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:398 → 479
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      pfam00169
      Location:288 → 379
      PH; PH domain
      pfam01412
      Location:490 → 606
      ArfGap; Putative GTPase activating protein for Arf
      cl00155
      Location:1119 → 1203
      UBQ; Ubiquitin-like proteins
      cl17171
      Location:1177 → 1290
      PH-like; Pleckstrin homology-like domain

    3. XM_015141087.2 → XP_014996573.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X2

      UniProtKB/TrEMBL
      F6YQS1
      Related
      ENSMMUP00000000634.4, ENSMMUT00000000685.4
      Conserved Domains (9) summary
      cd09490
      Location:4 → 66
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      smart00454
      Location:12 → 64
      SAM; Sterile alpha motif
      cd04385
      Location:911 → 1086
      RhoGAP_ARAP; RhoGAP_ARAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ...
      cd13253
      Location:289 → 381
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:398 → 479
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      pfam00169
      Location:288 → 379
      PH; PH domain
      pfam00788
      Location:1119 → 1211
      RA; Ras association (RalGDS/AF-6) domain
      pfam01412
      Location:490 → 606
      ArfGap; Putative GTPase activating protein for Arf
      cl17171
      Location:1214 → 1333
      PH-like; Pleckstrin homology-like domain

    4. XM_015141085.2 → XP_014996571.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QLW8, G7MVC0
      Conserved Domains (9) summary
      cd09490
      Location:4 → 66
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      smart00454
      Location:12 → 64
      SAM; Sterile alpha motif
      cd04385
      Location:911 → 1086
      RhoGAP_ARAP; RhoGAP_ARAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ...
      cd13253
      Location:289 → 381
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:398 → 479
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      pfam00169
      Location:288 → 379
      PH; PH domain
      pfam00788
      Location:1119 → 1211
      RA; Ras association (RalGDS/AF-6) domain
      pfam01412
      Location:490 → 606
      ArfGap; Putative GTPase activating protein for Arf
      cl17171
      Location:1214 → 1333
      PH-like; Pleckstrin homology-like domain

    5. XM_015141090.2 → XP_014996576.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X5

      UniProtKB/TrEMBL
      G7MVC0
      Conserved Domains (7) summary
      cd04385
      Location:833 → 1008
      RhoGAP_ARAP; RhoGAP_ARAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ...
      cd13253
      Location:211 → 303
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:320 → 401
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      pfam00169
      Location:210 → 301
      PH; PH domain
      pfam00788
      Location:1041 → 1133
      RA; Ras association (RalGDS/AF-6) domain
      pfam01412
      Location:412 → 528
      ArfGap; Putative GTPase activating protein for Arf
      cl17171
      Location:1136 → 1255
      PH-like; Pleckstrin homology-like domain

    6. XM_015141086.2 → XP_014996572.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QLW8, G7MVC0
      Related
      ENSMMUP00000049043.2, ENSMMUT00000076305.2
      Conserved Domains (9) summary
      cd09490
      Location:4 → 66
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      smart00454
      Location:12 → 64
      SAM; Sterile alpha motif
      cd04385
      Location:911 → 1086
      RhoGAP_ARAP; RhoGAP_ARAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ...
      cd13253
      Location:289 → 381
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:398 → 479
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      pfam00169
      Location:288 → 379
      PH; PH domain
      pfam00788
      Location:1119 → 1211
      RA; Ras association (RalGDS/AF-6) domain
      pfam01412
      Location:490 → 606
      ArfGap; Putative GTPase activating protein for Arf
      cl17171
      Location:1214 → 1333
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials