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    EPHA5 EPH receptor A5 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712074, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EPHA5provided by VGNC
    Official Full Name
    EPH receptor A5provided by VGNC
    Primary source
    VGNC:VGNC:72238
    See related
    Ensembl:ENSMMUG00000014468
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See EPHA5 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (67915494..68277677)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (68721645..69113311)

    Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106998383 Neighboring gene U2 spliceosomal RNA Neighboring gene arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 pseudogene Neighboring gene dipeptidyl peptidase 3-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane-ephrin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ephrin type-A receptor 5
    XP_001109851.4
    XP_028704382.1
    XP_028704383.1
    XP_028704384.1
    XP_028704385.1
    XP_028704386.1
    XP_028704387.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041758.1 Reference Mmul_10 Primary Assembly

      Range
      67915494..68277677
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028848552.1 → XP_028704385.1  ephrin type-A receptor 5 isoform X5

      UniProtKB/TrEMBL
      A0A5F8AC63
      Related
      ENSMMUP00000074561.1, ENSMMUT00000092196.1
      Conserved Domains (5) summary
      cd09546
      Location:854 → 919
      SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
      cd10483
      Location:60 → 232
      EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
      cd00063
      Location:357 → 447
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:559 → 825
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam14575
      Location:467 → 559
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

    2. XM_028848554.1 → XP_028704387.1  ephrin type-A receptor 5 isoform X7

      UniProtKB/TrEMBL
      F7B9U0
      Related
      ENSMMUP00000018999.4, ENSMMUT00000020298.4
      Conserved Domains (5) summary
      cd09546
      Location:802 → 867
      SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
      cd10483
      Location:60 → 232
      EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
      cd00063
      Location:305 → 395
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:507 → 773
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam14575
      Location:415 → 507
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

    3. XM_028848553.1 → XP_028704386.1  ephrin type-A receptor 5 isoform X6

      Conserved Domains (5) summary
      cd10483
      Location:60 → 232
      EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
      cd00063
      Location:357 → 447
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:558 → 824
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam14575
      Location:466 → 558
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl15755
      Location:853 → 891
      SAM_superfamily; SAM (Sterile alpha motif )

    4. XM_001109851.4 → XP_001109851.4  ephrin type-A receptor 5 isoform X1

      UniProtKB/TrEMBL
      F7GJT5
      Related
      ENSMMUP00000019000.4, ENSMMUT00000020299.4
      Conserved Domains (6) summary
      cd09546
      Location:966 → 1031
      SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
      cd10483
      Location:60 → 232
      EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
      cd00063
      Location:469 → 559
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:671 → 937
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:359 → 452
      fn3; Fibronectin type III domain
      pfam14575
      Location:579 → 671
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

    5. XM_028848550.1 → XP_028704383.1  ephrin type-A receptor 5 isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZLZ8
      Related
      ENSMMUP00000065640.1, ENSMMUT00000099159.1
      Conserved Domains (6) summary
      cd09546
      Location:944 → 1009
      SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
      cd10483
      Location:60 → 232
      EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
      cd00063
      Location:469 → 559
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:649 → 915
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:359 → 452
      fn3; Fibronectin type III domain
      pfam14575
      Location:579 → 649
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

    6. XM_028848549.1 → XP_028704382.1  ephrin type-A receptor 5 isoform X2

      UniProtKB/TrEMBL
      G7MT85
      Conserved Domains (6) summary
      cd09546
      Location:965 → 1030
      SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
      cd10483
      Location:60 → 232
      EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
      cd00063
      Location:469 → 559
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:670 → 936
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:359 → 452
      fn3; Fibronectin type III domain
      pfam14575
      Location:578 → 670
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

    7. XM_028848551.1 → XP_028704384.1  ephrin type-A receptor 5 isoform X4

      Conserved Domains (6) summary
      cd09546
      Location:943 → 1008
      SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
      cd10483
      Location:60 → 232
      EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
      cd00063
      Location:469 → 559
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:648 → 914
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:359 → 452
      fn3; Fibronectin type III domain
      pfam14575
      Location:578 → 648
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    Nucleotide Protein
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