REV3L REV3 like, DNA directed polymerase zeta catalytic subunit [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: REV3Lprovided by VGNC
Official Full Name: REV3 like, DNA directed polymerase zeta catalytic subunitprovided by VGNC
Primary source: VGNC:VGNC:76900
See related: Ensembl:ENSMMUG00000021533
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 37

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	4	NC_041757.1 (14931216..15120396, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	4	NC_027896.1 (156475603..156665204)

Chromosome 4 - NC_041757.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH18317 (e-PCR)
- UniSTS:88365

D3S2934E (e-PCR)
- UniSTS:150918

RH119655 (e-PCR)
- UniSTS:133020

csnprev3l-pcr10-1 (e-PCR)
- UniSTS:243132

csnprev3l-pcr14-1 (e-PCR)
- UniSTS:243135

csnprev3l-pcr14-3 (e-PCR)
- UniSTS:243137

csnprev3l-pcr14-5 (e-PCR)
- UniSTS:243139

csnprev3l-pcr14-6 (e-PCR)
- UniSTS:243140

csnprev3l-pcr14-7 (e-PCR)
- UniSTS:243141

csnprev3l-pcr15-1 (e-PCR)
- UniSTS:243142

csnprev3l-pcr21-1 (e-PCR)
- UniSTS:243145

csnprev3l-pcr29-1 (e-PCR)
- UniSTS:243149

RH103687 (e-PCR)
- UniSTS:98012

REV3L (e-PCR)
- UniSTS:504557

RH78825 (e-PCR)
- UniSTS:90108

G65600 (e-PCR)
- UniSTS:225535

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables DNA-directed DNA polymerase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables nucleotide binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in double-strand break repair via homologous recombination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in error-prone translesion synthesis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
part_of zeta DNA polymerase complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: DNA polymerase zeta catalytic subunit

Names: REV3-like, catalytic subunit of DNA polymerase zeta; REV3-like, polymerase (DNA directed), zeta, catalytic subunit

XP_014993056.2

EC 2.7.7.7

XP_028702867.1

EC 2.7.7.7

XP_028702868.1

EC 2.7.7.7

XP_028702869.1

EC 2.7.7.7

XP_028702870.1

EC 2.7.7.7

XP_028702871.1

EC 2.7.7.7

XP_028702872.1

EC 2.7.7.7

XP_028702873.1

EC 2.7.7.7

XP_028702874.1

EC 2.7.7.7

XP_028702875.1

EC 2.7.7.7

XP_028702876.1

EC 2.7.7.7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041757.1 Reference Mmul_10 Primary Assembly

Range

14931216..15120396 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028847035.1 → XP_028702868.1 DNA polymerase zeta catalytic subunit isoform X2

UniProtKB/TrEMBL

F7FBB2

Conserved Domains (5) summary

cd05778
Location:2291 → 2555

DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase

cd05534
Location:2581 → 3029

POLBc_zeta; DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production ...

PTZ00166
Location:6 → 182

PTZ00166; DNA polymerase delta catalytic subunit; Provisional

pfam15735
Location:747 → 1133

DUF4683; Domain of unknown function (DUF4683)

pfam14260
Location:3065 → 3132

zf-C4pol; C4-type zinc-finger of DNA polymerase delta
XM_028847036.1 → XP_028702869.1 DNA polymerase zeta catalytic subunit isoform X3

UniProtKB/TrEMBL

F7FBB2

Conserved Domains (5) summary

cd05778
Location:2292 → 2530

DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase

cd05534
Location:2556 → 3004

POLBc_zeta; DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production ...

PTZ00166
Location:6 → 182

PTZ00166; DNA polymerase delta catalytic subunit; Provisional

pfam15735
Location:748 → 1134

DUF4683; Domain of unknown function (DUF4683)

pfam14260
Location:3040 → 3107

zf-C4pol; C4-type zinc-finger of DNA polymerase delta
XM_028847034.1 → XP_028702867.1 DNA polymerase zeta catalytic subunit isoform X1

UniProtKB/TrEMBL

F7FBB2

Conserved Domains (5) summary

cd05778
Location:2292 → 2556

DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase

cd05534
Location:2582 → 3030

POLBc_zeta; DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production ...

PTZ00166
Location:6 → 182

PTZ00166; DNA polymerase delta catalytic subunit; Provisional

pfam15735
Location:748 → 1134

DUF4683; Domain of unknown function (DUF4683)

pfam14260
Location:3066 → 3133

zf-C4pol; C4-type zinc-finger of DNA polymerase delta
XM_028847037.1 → XP_028702870.1 DNA polymerase zeta catalytic subunit isoform X5

UniProtKB/TrEMBL

G7MQQ8

Conserved Domains (5) summary

cd05778
Location:2214 → 2478

DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase

cd05534
Location:2504 → 2952

POLBc_zeta; DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production ...

pfam15735
Location:670 → 1056

DUF4683; Domain of unknown function (DUF4683)

pfam03104
Location:23 → 113

DNA_pol_B_exo1; DNA polymerase family B, exonuclease domain

pfam14260
Location:2988 → 3055

zf-C4pol; C4-type zinc-finger of DNA polymerase delta
XM_028847039.1 → XP_028702872.1 DNA polymerase zeta catalytic subunit isoform X5

UniProtKB/TrEMBL

G7MQQ8

Conserved Domains (5) summary

cd05778
Location:2214 → 2478

DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase

cd05534
Location:2504 → 2952

POLBc_zeta; DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production ...

pfam15735
Location:670 → 1056

DUF4683; Domain of unknown function (DUF4683)

pfam03104
Location:23 → 113

DNA_pol_B_exo1; DNA polymerase family B, exonuclease domain

pfam14260
Location:2988 → 3055

zf-C4pol; C4-type zinc-finger of DNA polymerase delta
XM_028847038.1 → XP_028702871.1 DNA polymerase zeta catalytic subunit isoform X5

UniProtKB/TrEMBL

G7MQQ8

Conserved Domains (5) summary

cd05778
Location:2214 → 2478

DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase

cd05534
Location:2504 → 2952

POLBc_zeta; DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production ...

pfam15735
Location:670 → 1056

DUF4683; Domain of unknown function (DUF4683)

pfam03104
Location:23 → 113

DNA_pol_B_exo1; DNA polymerase family B, exonuclease domain

pfam14260
Location:2988 → 3055

zf-C4pol; C4-type zinc-finger of DNA polymerase delta
XM_028847041.1 → XP_028702874.1 DNA polymerase zeta catalytic subunit isoform X7

UniProtKB/TrEMBL

G7MQQ8

Conserved Domains (4) summary

cd05778
Location:2170 → 2434

DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase

cd05534
Location:2460 → 2908

POLBc_zeta; DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production ...

pfam15735
Location:626 → 1012

DUF4683; Domain of unknown function (DUF4683)

pfam14260
Location:2944 → 3011

zf-C4pol; C4-type zinc-finger of DNA polymerase delta
XM_015137570.2 → XP_014993056.2 DNA polymerase zeta catalytic subunit isoform X4

UniProtKB/TrEMBL

A0A5F7Z8L5, F7FBB2

Related

ENSMMUP00000061482.1, ENSMMUT00000104986.1

Conserved Domains (5) summary

cd05778
Location:2291 → 2529

DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase

cd05534
Location:2555 → 3003

POLBc_zeta; DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production ...

PTZ00166
Location:6 → 182

PTZ00166; DNA polymerase delta catalytic subunit; Provisional

pfam15735
Location:747 → 1133

DUF4683; Domain of unknown function (DUF4683)

pfam14260
Location:3039 → 3106

zf-C4pol; C4-type zinc-finger of DNA polymerase delta
XM_028847040.1 → XP_028702873.1 DNA polymerase zeta catalytic subunit isoform X6

UniProtKB/TrEMBL

A0A5F7ZHD9, G7MQQ8

Related

ENSMMUP00000065006.1, ENSMMUT00000081245.1

Conserved Domains (5) summary

cd05778
Location:2213 → 2451

DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase

cd05534
Location:2477 → 2925

POLBc_zeta; DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production ...

pfam15735
Location:669 → 1055

DUF4683; Domain of unknown function (DUF4683)

pfam03104
Location:23 → 113

DNA_pol_B_exo1; DNA polymerase family B, exonuclease domain

pfam14260
Location:2961 → 3028

zf-C4pol; C4-type zinc-finger of DNA polymerase delta
XM_028847043.1 → XP_028702876.1 DNA polymerase zeta catalytic subunit isoform X9

UniProtKB/TrEMBL

A0A5F8A920

Conserved Domains (4) summary

cd05778
Location:2292 → 2530

DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase

PTZ00166
Location:6 → 182

PTZ00166; DNA polymerase delta catalytic subunit; Provisional

pfam15735
Location:748 → 1134

DUF4683; Domain of unknown function (DUF4683)

cl10023
Location:2556 → 2676

POLBc; DNA polymerase type-B family catalytic domain. DNA-directed DNA polymerases elongate DNA by adding nucleotide triphosphate (dNTP) residues to the 5'-end of the growing chain of DNA. DNA-directed DNA polymerases are multifunctional with both synthetic ...
XM_028847042.1 → XP_028702875.1 DNA polymerase zeta catalytic subunit isoform X8

UniProtKB/TrEMBL

A0A5F8A920

Conserved Domains (4) summary

cd05778
Location:2292 → 2556

DNA_polB_zeta_exo; inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase zeta, a family-B DNA polymerase

PTZ00166
Location:6 → 182

PTZ00166; DNA polymerase delta catalytic subunit; Provisional

pfam15735
Location:748 → 1134

DUF4683; Domain of unknown function (DUF4683)

cl10023
Location:2582 → 2702

POLBc; DNA polymerase type-B family catalytic domain. DNA-directed DNA polymerases elongate DNA by adding nucleotide triphosphate (dNTP) residues to the 5'-end of the growing chain of DNA. DNA-directed DNA polymerases are multifunctional with both synthetic ...