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    EPHA3 EPH receptor A3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694583, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EPHA3provided by VGNC
    Official Full Name
    EPH receptor A3provided by VGNC
    Primary source
    VGNC:VGNC:72236
    See related
    Ensembl:ENSMMUG00000008242
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See EPHA3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (182614119..182972395, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (13849263..14211854)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U3 Neighboring gene uncharacterized LOC100429167 Neighboring gene protein FAM133B pseudogene Neighboring gene little elongation complex subunit 2 pseudogene Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane-ephrin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ephrin type-A receptor 3
    XP_001083136.1
    XP_014984688.1
    XP_028700543.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      182614119..182972395 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015129202.2 → XP_014984688.1  ephrin type-A receptor 3 isoform X2

      UniProtKB/TrEMBL
      F7HDY6
      Conserved Domains (8) summary
      cd09544
      Location:912 → 974
      SAM_EPH-A3; SAM domain of EPH-A3 subfamily of tyrosine kinase receptors
      smart00454
      Location:908 → 975
      SAM; Sterile alpha motif
      cd10481
      Location:29 → 201
      EphR_LBD_A3; Ligand Binding Domain of Ephrin type-A Receptor 3
      cd00063
      Location:437 → 527
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:616 → 882
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:327 → 417
      fn3; Fibronectin type III domain
      pfam07714
      Location:621 → 878
      Pkinase_Tyr; Protein tyrosine kinase
      pfam14575
      Location:554 → 616
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

    2. XM_001083136.2 → XP_001083136.1  ephrin type-A receptor 3 isoform X1

      See identical proteins and their annotated locations for XP_001083136.1

      UniProtKB/TrEMBL
      A0A5F7ZKD5, F7HDY6
      Related
      ENSMMUP00000065088.1, ENSMMUT00000105160.1
      Conserved Domains (8) summary
      cd09544
      Location:913 → 975
      SAM_EPH-A3; SAM domain of EPH-A3 subfamily of tyrosine kinase receptors
      smart00454
      Location:909 → 976
      SAM; Sterile alpha motif
      cd10481
      Location:29 → 201
      EphR_LBD_A3; Ligand Binding Domain of Ephrin type-A Receptor 3
      cd00063
      Location:437 → 528
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:617 → 883
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:327 → 417
      fn3; Fibronectin type III domain
      pfam07714
      Location:622 → 879
      Pkinase_Tyr; Protein tyrosine kinase
      pfam14575
      Location:555 → 617
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

    3. XM_028844710.1 → XP_028700543.1  ephrin type-A receptor 3 isoform X3

      Conserved Domains (4) summary
      cd10481
      Location:29 → 201
      EphR_LBD_A3; Ligand Binding Domain of Ephrin type-A Receptor 3
      cd00063
      Location:437 → 528
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07699
      Location:269 → 303
      Ephrin_rec_like; Putative ephrin-receptor like
      pfam00041
      Location:327 → 417
      fn3; Fibronectin type III domain
    Nucleotide Protein
    Heading Accession and Version

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