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    LOC718576 caspase recruitment domain-containing protein 8 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718576, updated on 14-Nov-2024

    Summary

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    Gene symbol
    LOC718576
    Gene description
    caspase recruitment domain-containing protein 8
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
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    Genomic context

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    See LOC718576 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (48174463..48213538, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (43539392..43577018, complement)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene DNA ligase 1 Neighboring gene zinc finger SWIM-type containing 9 Neighboring gene caspase recruitment domain-containing protein 8 Neighboring gene vomeronasal 1 receptor macMulV1R-ps1040 pseudogene Neighboring gene zinc finger protein 114 Neighboring gene outer dynein arm docking complex subunit 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activator activity involved in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NLRP3 inflammasome complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    caspase recruitment domain-containing protein 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      48174463..48213538 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015124453.2 → XP_014979939.2  caspase recruitment domain-containing protein 8 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZNU3
      Conserved Domains (1) summary
      pfam13553
      Location:90 → 343
      FIIND; Function to find

    2. XM_015124454.2 → XP_014979940.2  caspase recruitment domain-containing protein 8 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZNU3
      Conserved Domains (1) summary
      pfam13553
      Location:90 → 343
      FIIND; Function to find

    3. XM_028838583.1 → XP_028694416.1  caspase recruitment domain-containing protein 8 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZNU3
      Conserved Domains (1) summary
      pfam13553
      Location:90 → 343
      FIIND; Function to find

    4. XM_028838584.1 → XP_028694417.1  caspase recruitment domain-containing protein 8 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZNU3
      Conserved Domains (1) summary
      pfam13553
      Location:90 → 343
      FIIND; Function to find

    5. XM_028838586.1 → XP_028694419.1  caspase recruitment domain-containing protein 8 isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZNU3
      Conserved Domains (1) summary
      pfam13553
      Location:65 → 318
      FIIND; Function to find

    6. XM_028838585.1 → XP_028694418.1  caspase recruitment domain-containing protein 8 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZNU3
      Conserved Domains (1) summary
      pfam13553
      Location:72 → 325
      FIIND; Function to find

    7. XM_028838589.1 → XP_028694422.1  caspase recruitment domain-containing protein 8 isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZNU3
      Conserved Domains (1) summary
      pfam13553
      Location:65 → 318
      FIIND; Function to find

    8. XM_028838587.1 → XP_028694420.1  caspase recruitment domain-containing protein 8 isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZNU3
      Conserved Domains (1) summary
      pfam13553
      Location:65 → 318
      FIIND; Function to find

    9. XM_028838588.1 → XP_028694421.1  caspase recruitment domain-containing protein 8 isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZNU3
      Conserved Domains (1) summary
      pfam13553
      Location:65 → 318
      FIIND; Function to find

    10. XM_002801323.3 → XP_002801369.3  caspase recruitment domain-containing protein 8 isoform X4

      UniProtKB/TrEMBL
      A0A5F8A9I1
      Conserved Domains (2) summary
      pfam13553
      Location:90 → 343
      FIIND; Function to find
      pfam00619
      Location:360 → 442
      CARD; Caspase recruitment domain
    Nucleotide Protein
    Heading Accession and Version

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