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    LRP3 LDL receptor related protein 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703776, updated on 17-Aug-2024

    Summary

    Official Symbol
    LRP3provided by VGNC
    Official Full Name
    LDL receptor related protein 3provided by VGNC
    Primary source
    VGNC:VGNC:74444
    See related
    Ensembl:ENSMMUG00000022872
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See LRP3 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (32660878..32674813)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (29149445..29163181)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene WD repeat domain 88 Neighboring gene transfer RNA threonine (anticodon AGU) Neighboring gene solute carrier family 7 member 10 Neighboring gene translation initiation factor IF-2-like Neighboring gene CCAAT enhancer binding protein alpha

    Genomic regions, transcripts, and products

    General protein information

    Preferred Names
    low-density lipoprotein receptor-related protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260541.1NP_001247470.1  low-density lipoprotein receptor-related protein 3

      See identical proteins and their annotated locations for NP_001247470.1

      Status: PROVISIONAL

      Source sequence(s)
      JV044861
      UniProtKB/TrEMBL
      A0A1D5R1C6, H9F593, I0FKF6
      Related
      ENSMMUP00000054110.2, ENSMMUT00000060228.2
      Conserved Domains (2) summary
      cd00041
      Location:43156
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00112
      Location:455489
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      32660878..32674813
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028838404.1XP_028694237.1  low-density lipoprotein receptor-related protein 3 isoform X1

      UniProtKB/TrEMBL
      H9F593
      Conserved Domains (2) summary
      cd00041
      Location:43156
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00112
      Location:455489
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    2. XM_028838405.1XP_028694238.1  low-density lipoprotein receptor-related protein 3 isoform X2

      UniProtKB/TrEMBL
      H9F593
      Conserved Domains (2) summary
      cd00041
      Location:42155
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00112
      Location:454488
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...