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    PAK1 p21 (RAC1) activated kinase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698585, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PAK1provided by VGNC
    Official Full Name
    p21 (RAC1) activated kinase 1provided by VGNC
    Primary source
    VGNC:VGNC:101373
    See related
    Ensembl:ENSMMUG00000001387
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PAK1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (70393251..70542828, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (69512538..69664087, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene glycerophosphodiester phosphodiesterase domain containing 4 Neighboring gene mitochondrial import receptor subunit TOM20 homolog pseudogene Neighboring gene translation initiation factor IF-2-like Neighboring gene U7 small nuclear RNA Neighboring gene uncharacterized LOC106993393

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of axonogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase PAK 1
    XP_014970742.2
    XP_014970744.2
    XP_014970746.2
    XP_014970747.2
    XP_014970748.2
    XP_014970749.2
    XP_014970750.2
    XP_014970751.2
    XP_014970752.2
    XP_028689681.1
    XP_028689682.1
    XP_028689683.1
    XP_028689684.1
    XP_028689685.1
    XP_028689686.1
    XP_028689687.1
    XP_028689688.1
    XP_028689689.1
    XP_028689690.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      70393251..70542828 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015115263.2 → XP_014970749.2  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RKP7, F7D0C3
      Conserved Domains (2) summary
      cd06654
      Location:270 → 565
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    2. XM_028833848.1 → XP_028689681.1  serine/threonine-protein kinase PAK 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5RKP7
      Conserved Domains (2) summary
      cd06654
      Location:269 → 564
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 128
      PBD; P21-Rho-binding domain

    3. XM_028833850.1 → XP_028689683.1  serine/threonine-protein kinase PAK 1 isoform X4

      UniProtKB/TrEMBL
      A0A1D5RKP7
      Conserved Domains (2) summary
      cd06654
      Location:253 → 548
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 128
      PBD; P21-Rho-binding domain

    4. XM_028833855.1 → XP_028689688.1  serine/threonine-protein kinase PAK 1 isoform X7

      UniProtKB/TrEMBL
      A0A1D5RKP7
      Conserved Domains (2) summary
      pfam00786
      Location:74 → 128
      PBD; P21-Rho-binding domain
      cl21453
      Location:270 → 519
      PKc_like; Protein Kinases, catalytic domain

    5. XM_015115258.2 → XP_014970744.2  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RKP7, F7D0C3
      Related
      ENSMMUP00000001853.4, ENSMMUT00000001966.4
      Conserved Domains (2) summary
      cd06654
      Location:270 → 565
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    6. XM_028833849.1 → XP_028689682.1  serine/threonine-protein kinase PAK 1 isoform X3

      UniProtKB/TrEMBL
      F6XUP1
      Conserved Domains (2) summary
      cd06647
      Location:283 → 538
      STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
      pfam00786
      Location:74 → 128
      PBD; P21-Rho-binding domain

    7. XM_015115264.2 → XP_014970750.2  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RKP7, F7D0C3
      Conserved Domains (2) summary
      cd06654
      Location:270 → 565
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    8. XM_015115256.2 → XP_014970742.2  serine/threonine-protein kinase PAK 1 isoform X5

      UniProtKB/TrEMBL
      A0A1D5RJE4, A0A1D5RKP7, H9EM79
      Conserved Domains (2) summary
      cd06654
      Location:249 → 544
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    9. XM_015115266.2 → XP_014970752.2  serine/threonine-protein kinase PAK 1 isoform X5

      UniProtKB/TrEMBL
      A0A1D5RJE4, A0A1D5RKP7, H9EM79
      Related
      ENSMMUP00000077300.1, ENSMMUT00000108089.1
      Conserved Domains (2) summary
      cd06654
      Location:249 → 544
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    10. XM_015115261.2 → XP_014970747.2  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RKP7, F7D0C3
      Conserved Domains (2) summary
      cd06654
      Location:270 → 565
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    11. XM_015115262.2 → XP_014970748.2  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RKP7, F7D0C3
      Conserved Domains (2) summary
      cd06654
      Location:270 → 565
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    12. XM_028833852.1 → XP_028689685.1  serine/threonine-protein kinase PAK 1 isoform X5

      UniProtKB/TrEMBL
      A0A1D5RJE4, A0A1D5RKP7, H9EM79
      Conserved Domains (2) summary
      cd06654
      Location:249 → 544
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    13. XM_015115265.2 → XP_014970751.2  serine/threonine-protein kinase PAK 1 isoform X5

      UniProtKB/TrEMBL
      A0A1D5RJE4, A0A1D5RKP7, H9EM79
      Related
      ENSMMUP00000070636.1, ENSMMUT00000085517.1
      Conserved Domains (2) summary
      cd06654
      Location:249 → 544
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    14. XM_028833851.1 → XP_028689684.1  serine/threonine-protein kinase PAK 1 isoform X5

      UniProtKB/TrEMBL
      A0A1D5RJE4, A0A1D5RKP7, H9EM79
      Conserved Domains (2) summary
      cd06654
      Location:249 → 544
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    15. XM_028833853.1 → XP_028689686.1  serine/threonine-protein kinase PAK 1 isoform X5

      UniProtKB/TrEMBL
      A0A1D5RJE4, A0A1D5RKP7, H9EM79
      Conserved Domains (2) summary
      cd06654
      Location:249 → 544
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    16. XM_028833857.1 → XP_028689690.1  serine/threonine-protein kinase PAK 1 isoform X8

      UniProtKB/TrEMBL
      A0A1D5RKP7, A0A5F7ZUG6
      Related
      ENSMMUP00000069304.1, ENSMMUT00000085837.1
      Conserved Domains (2) summary
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain
      cl21453
      Location:249 → 498
      PKc_like; Protein Kinases, catalytic domain

    17. XM_028833856.1 → XP_028689689.1  serine/threonine-protein kinase PAK 1 isoform X8

      UniProtKB/TrEMBL
      A0A1D5RKP7, A0A5F7ZUG6
      Conserved Domains (2) summary
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain
      cl21453
      Location:249 → 498
      PKc_like; Protein Kinases, catalytic domain

    18. XM_028833854.1 → XP_028689687.1  serine/threonine-protein kinase PAK 1 isoform X6

      UniProtKB/TrEMBL
      F6XUP1, F7D0B4
      Related
      ENSMMUP00000076728.1, ENSMMUT00000108785.1
      Conserved Domains (2) summary
      cd06647
      Location:262 → 517
      STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
      pfam00786
      Location:74 → 128
      PBD; P21-Rho-binding domain

    19. XM_015115260.2 → XP_014970746.2  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RKP7, F7D0C3
      Conserved Domains (2) summary
      cd06654
      Location:270 → 565
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain
    Nucleotide Protein
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