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    DENND2B DENN domain containing 2B [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705444, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DENND2Bprovided by VGNC
    Official Full Name
    DENN domain containing 2Bprovided by VGNC
    Primary source
    VGNC:VGNC:77898
    See related
    Ensembl:ENSMMUG00000021830
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    ST5
    Orthologs
    human mouse all
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    Genomic context

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    See DENND2B in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (56804392..56982201)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (57607607..57786385)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene chromosome 14 C11orf16 homolog Neighboring gene achaete-scute family bHLH transcription factor 3 Neighboring gene A-kinase interacting protein 1 Neighboring gene uncharacterized LOC106993341 Neighboring gene small nucleolar RNA SNORA3/SNORA45 family Neighboring gene small nucleolar RNA SNORA3/SNORA45 family Neighboring gene ribosomal protein L27a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in positive regulation of ERK1 and ERK2 cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    suppression of tumorigenicity 5 protein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      56804392..56982201
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028833713.1 → XP_028689546.1  suppression of tumorigenicity 5 protein isoform X1

      UniProtKB/TrEMBL
      A0A8J8YL53, F7EMG0, F7EMG5, G7MZB1, H9FYX2
      Conserved Domains (3) summary
      smart00801
      Location:1023 → 1089
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:697 → 784
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:791 → 972
      DENN; DENN (AEX-3) domain

    2. XM_028833717.1 → XP_028689550.1  suppression of tumorigenicity 5 protein isoform X1

      UniProtKB/TrEMBL
      A0A8J8YL53, F7EMG0, F7EMG5, G7MZB1, H9FYX2
      Conserved Domains (3) summary
      smart00801
      Location:1023 → 1089
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:697 → 784
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:791 → 972
      DENN; DENN (AEX-3) domain

    3. XM_015114917.2 → XP_014970403.1  suppression of tumorigenicity 5 protein isoform X4

      UniProtKB/TrEMBL
      F7EMF4, I2CXJ1
      Conserved Domains (3) summary
      smart00801
      Location:603 → 669
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:277 → 364
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:371 → 552
      DENN; DENN (AEX-3) domain

    4. XM_028833715.1 → XP_028689548.1  suppression of tumorigenicity 5 protein isoform X1

      UniProtKB/TrEMBL
      A0A8J8YL53, F7EMG0, F7EMG5, G7MZB1, H9FYX2
      Conserved Domains (3) summary
      smart00801
      Location:1023 → 1089
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:697 → 784
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:791 → 972
      DENN; DENN (AEX-3) domain

    5. XM_015114910.2 → XP_014970396.1  suppression of tumorigenicity 5 protein isoform X1

      UniProtKB/TrEMBL
      A0A8J8YL53, F7EMG0, F7EMG5, G7MZB1, H9FYX2
      Conserved Domains (3) summary
      smart00801
      Location:1023 → 1089
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:697 → 784
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:791 → 972
      DENN; DENN (AEX-3) domain

    6. XM_028833714.1 → XP_028689547.1  suppression of tumorigenicity 5 protein isoform X1

      UniProtKB/TrEMBL
      A0A8J8YL53, F7EMG0, F7EMG5, G7MZB1, H9FYX2
      Conserved Domains (3) summary
      smart00801
      Location:1023 → 1089
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:697 → 784
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:791 → 972
      DENN; DENN (AEX-3) domain

    7. XM_015114911.2 → XP_014970397.1  suppression of tumorigenicity 5 protein isoform X1

      UniProtKB/TrEMBL
      A0A8J8YL53, F7EMG0, F7EMG5, G7MZB1, H9FYX2
      Related
      ENSMMUP00000043148.2, ENSMMUT00000057474.2
      Conserved Domains (3) summary
      smart00801
      Location:1023 → 1089
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:697 → 784
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:791 → 972
      DENN; DENN (AEX-3) domain

    8. XM_015114908.2 → XP_014970394.1  suppression of tumorigenicity 5 protein isoform X1

      UniProtKB/TrEMBL
      A0A8J8YL53, F7EMG0, F7EMG5, G7MZB1, H9FYX2
      Related
      ENSMMUP00000078664.1, ENSMMUT00000107252.1
      Conserved Domains (3) summary
      smart00801
      Location:1023 → 1089
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:697 → 784
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:791 → 972
      DENN; DENN (AEX-3) domain

    9. XM_015114916.2 → XP_014970402.1  suppression of tumorigenicity 5 protein isoform X4

      UniProtKB/TrEMBL
      F7EMF4, I2CXJ1
      Related
      ENSMMUP00000028748.4, ENSMMUT00000030718.4
      Conserved Domains (3) summary
      smart00801
      Location:603 → 669
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:277 → 364
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:371 → 552
      DENN; DENN (AEX-3) domain

    10. XM_015114914.2 → XP_014970400.1  suppression of tumorigenicity 5 protein isoform X1

      UniProtKB/TrEMBL
      A0A8J8YL53, F7EMG0, F7EMG5, G7MZB1, H9FYX2
      Related
      ENSMMUP00000028746.4, ENSMMUT00000030716.4
      Conserved Domains (3) summary
      smart00801
      Location:1023 → 1089
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:697 → 784
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:791 → 972
      DENN; DENN (AEX-3) domain

    11. XM_015114919.2 → XP_014970405.1  suppression of tumorigenicity 5 protein isoform X4

      UniProtKB/TrEMBL
      F7EMF4, I2CXJ1
      Conserved Domains (3) summary
      smart00801
      Location:603 → 669
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:277 → 364
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:371 → 552
      DENN; DENN (AEX-3) domain

    12. XM_015114907.2 → XP_014970393.1  suppression of tumorigenicity 5 protein isoform X2

      UniProtKB/TrEMBL
      A0A8J8YL53, G7MZB1, H9FYX2
      Conserved Domains (3) summary
      smart00801
      Location:1043 → 1109
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:717 → 804
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:811 → 992
      DENN; DENN (AEX-3) domain

    13. XM_015114913.2 → XP_014970399.1  suppression of tumorigenicity 5 protein isoform X1

      UniProtKB/TrEMBL
      A0A8J8YL53, F7EMG0, F7EMG5, G7MZB1, H9FYX2
      Conserved Domains (3) summary
      smart00801
      Location:1023 → 1089
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:697 → 784
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:791 → 972
      DENN; DENN (AEX-3) domain

    14. XM_015114918.2 → XP_014970404.1  suppression of tumorigenicity 5 protein isoform X4

      UniProtKB/TrEMBL
      F7EMF4, I2CXJ1
      Conserved Domains (3) summary
      smart00801
      Location:603 → 669
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:277 → 364
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:371 → 552
      DENN; DENN (AEX-3) domain

    15. XM_028833718.1 → XP_028689551.1  suppression of tumorigenicity 5 protein isoform X3

      UniProtKB/TrEMBL
      A0A1D5Q533
      Conserved Domains (2) summary
      smart00800
      Location:697 → 784
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:791 → 972
      DENN; DENN (AEX-3) domain

    16. XM_028833712.1 → XP_028689545.1  suppression of tumorigenicity 5 protein isoform X1

      UniProtKB/TrEMBL
      A0A8J8YL53, F7EMG0, F7EMG5, G7MZB1, H9FYX2
      Related
      ENSMMUP00000060195.2, ENSMMUT00000053237.2
      Conserved Domains (3) summary
      smart00801
      Location:1023 → 1089
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:697 → 784
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:791 → 972
      DENN; DENN (AEX-3) domain

    17. XM_028833719.1 → XP_028689552.1  suppression of tumorigenicity 5 protein isoform X4

      UniProtKB/TrEMBL
      F7EMF4, I2CXJ1
      Conserved Domains (3) summary
      smart00801
      Location:603 → 669
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:277 → 364
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:371 → 552
      DENN; DENN (AEX-3) domain
    Nucleotide Protein
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