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    LOC701504 immunoglobulin kappa light chain [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701504, updated on 9-Nov-2023

    Summary

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    Gene symbol
    LOC701504
    Gene description
    immunoglobulin kappa light chain
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    IGK; IGK@
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    Genomic context

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    See LOC701504 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (17331100..18131070)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (90319457..90324214, complement)

    Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene immunoglobulin kappa variable 1-27-like Neighboring gene immunoglobulin kappa variable 2-30-like Neighboring gene immunoglobulin kappa variable 1-9-like Neighboring gene immunoglobulin kappa variable 1-39-like Neighboring gene U6 spliceosomal RNA Neighboring gene immunoglobulin kappa variable 2D-29-like Neighboring gene developmentally-regulated GTP-binding protein 1 pseudogene Neighboring gene immunoglobulin kappa variable 1-39-like Neighboring gene immunoglobulin kappa variable 1-9 Neighboring gene uncharacterized LOC106993066 Neighboring gene uncharacterized LOC106993052 Neighboring gene immunoglobulin kappa variable 1-12-like Neighboring gene immunoglobulin kappa variable 3-11-like Neighboring gene immunoglobulin kappa variable 3-11-like Neighboring gene protein IMPACT pseudogene Neighboring gene DNA-directed RNA polymerases I, II, and III subunit RPABC4-like Neighboring gene immunoglobulin kappa variable 4-1-like Neighboring gene casein kinase I pseudogene Neighboring gene ankyrin repeat domain-containing protein 36B-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Zhang R, et al. Sci Transl Med, 2016 Apr 27. PMID 27122615, Free PMC Article
    2. Isolation of potent neutralizing monoclonal antibodies from an SIV-Infected rhesus macaque by phage display. Kuwata T, et al. AIDS Res Hum Retroviruses, 2011 May. PMID 20854170
    3. Use of molecular modeling and site-directed mutagenesis to define the structural basis for the immune response to carbohydrate xenoantigens. Kearns-Jonker M, et al. BMC Immunol, 2007 Mar 12. PMID 17352819, Free PMC Article
    4. Characterization of the three immunoglobulin G subclasses of macaques. Calvas P, et al. Scand J Immunol, 1999 Jun. PMID 10354371
    5. Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques. He WT, et al. Sci Transl Med, 2022 Aug 10. PMID 35947674, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immunoglobulin production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    immunoglobulin kappa light chain
    Names
    Mamu IGLK-rh
    Mamu IgK-rh
    anti-HIV immunoglobulin light chain variable region
    anti-SARS-CoV-2 immunoglobulin heavy chain variable region
    anti-SIV env immunoglobulin ITS19 light chain variable region
    anti-SIV env immunoglobulin ITS50 light chain variable region
    anti-SIV env immunoglobulin ITS67 light chain variable region
    immunglobulin light chain variable region
    immunoglobulin G light chain variable region
    immunoglobulin kappa chain constant region
    immunoglobulin kappa chain joining region
    immunoglobulin kappa chain variable region
    immunoglobulin kappa light chain constant region
    immunoglobulin kappa light chain variable region
    immunoglobulin kappa variable region
    immunoglobulin light chain variable region

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041766.1 Reference Mmul_10 Primary Assembly

      Range
      17331100..18131070
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028832098.1 → XP_028687931.1  immunoglobulin kappa light chain isoform X50

      Conserved Domains (2) summary
      cd07699
      Location:132 → 231
      IgC_L; Immunoglobulin Constant domain
      cl11960
      Location:22 → 126
      Ig; Immunoglobulin domain

    2. XM_028832095.1 → XP_028687928.1  immunoglobulin kappa light chain isoform X47

      Conserved Domains (2) summary
      cd04980
      Location:22 → 126
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:132 → 231
      IgC_L; Immunoglobulin Constant domain

    3. XM_028832097.1 → XP_028687930.1  immunoglobulin kappa light chain isoform X49

      Conserved Domains (2) summary
      cd04980
      Location:22 → 126
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:132 → 231
      IgC_L; Immunoglobulin Constant domain

    4. XM_028832076.1 → XP_028687909.1  immunoglobulin kappa light chain isoform X30

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    5. XM_028832074.1 → XP_028687907.1  immunoglobulin kappa light chain isoform X28

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    6. XM_028832079.1 → XP_028687912.1  immunoglobulin kappa light chain isoform X33

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    7. XM_028832075.1 → XP_028687908.1  immunoglobulin kappa light chain isoform X29

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    8. XM_028832078.1 → XP_028687911.1  immunoglobulin kappa light chain isoform X32

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    9. XM_028832073.1 → XP_028687906.1  immunoglobulin kappa light chain isoform X27

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    10. XM_028832080.1 → XP_028687913.1  immunoglobulin kappa light chain isoform X34

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    11. XM_028832077.1 → XP_028687910.1  immunoglobulin kappa light chain isoform X31

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    12. XM_028832094.1 → XP_028687927.1  immunoglobulin kappa light chain isoform X46

      Conserved Domains (2) summary
      cd04980
      Location:22 → 126
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:132 → 231
      IgC_L; Immunoglobulin Constant domain

    13. XM_028832096.1 → XP_028687929.1  immunoglobulin kappa light chain isoform X48

      Conserved Domains (2) summary
      cd04980
      Location:22 → 126
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:132 → 231
      IgC_L; Immunoglobulin Constant domain

    14. XM_028832081.1 → XP_028687914.1  immunoglobulin kappa light chain isoform X35

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    15. XM_028832083.1 → XP_028687916.1  immunoglobulin kappa light chain isoform X36

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    16. XM_028832085.1 → XP_028687918.1  immunoglobulin kappa light chain isoform X38

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    17. XM_028832084.1 → XP_028687917.1  immunoglobulin kappa light chain isoform X37

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    18. XM_028832060.1 → XP_028687893.1  immunoglobulin kappa light chain isoform X14

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    19. XM_028832058.1 → XP_028687891.1  immunoglobulin kappa light chain isoform X12

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    20. XM_028832061.1 → XP_028687894.1  immunoglobulin kappa light chain isoform X15

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    21. XM_028832059.1 → XP_028687892.1  immunoglobulin kappa light chain isoform X13

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    22. XM_028832089.1 → XP_028687922.1  immunoglobulin kappa light chain isoform X42

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    23. XM_028832071.1 → XP_028687904.1  immunoglobulin kappa light chain isoform X25

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    24. XM_028832069.1 → XP_028687902.1  immunoglobulin kappa light chain isoform X23

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    25. XM_028832072.1 → XP_028687905.1  immunoglobulin kappa light chain isoform X26

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    26. XM_028832070.1 → XP_028687903.1  immunoglobulin kappa light chain isoform X24

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    27. XM_028832052.1 → XP_028687885.1  immunoglobulin kappa light chain isoform X6

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    28. XM_028832050.1 → XP_028687883.1  immunoglobulin kappa light chain isoform X4

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    29. XM_028832048.1 → XP_028687881.1  immunoglobulin kappa light chain isoform X2

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    30. XM_028832049.1 → XP_028687882.1  immunoglobulin kappa light chain isoform X3

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    31. XM_028832051.1 → XP_028687884.1  immunoglobulin kappa light chain isoform X5

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    32. XM_028832047.1 → XP_028687880.1  immunoglobulin kappa light chain isoform X1

      Conserved Domains (2) summary
      cd04980
      Location:24 → 129
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:135 → 234
      IgC_L; Immunoglobulin Constant domain

    33. XM_028832056.1 → XP_028687889.1  immunoglobulin kappa light chain isoform X10

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    34. XM_028832054.1 → XP_028687887.1  immunoglobulin kappa light chain isoform X8

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    35. XM_028832053.1 → XP_028687886.1  immunoglobulin kappa light chain isoform X7

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    36. XM_028832057.1 → XP_028687890.1  immunoglobulin kappa light chain isoform X11

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    37. XM_028832055.1 → XP_028687888.1  immunoglobulin kappa light chain isoform X9

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    38. XM_028832066.1 → XP_028687899.1  immunoglobulin kappa light chain isoform X20

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    39. XM_028832063.1 → XP_028687896.1  immunoglobulin kappa light chain isoform X17

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    40. XM_028832068.1 → XP_028687901.1  immunoglobulin kappa light chain isoform X22

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    41. XM_028832067.1 → XP_028687900.1  immunoglobulin kappa light chain isoform X21

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    42. XM_028832062.1 → XP_028687895.1  immunoglobulin kappa light chain isoform X16

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    43. XM_028832065.1 → XP_028687898.1  immunoglobulin kappa light chain isoform X19

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    44. XM_028832064.1 → XP_028687897.1  immunoglobulin kappa light chain isoform X18

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    45. XM_028832087.1 → XP_028687920.1  immunoglobulin kappa light chain isoform X40

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    46. XM_028832086.1 → XP_028687919.1  immunoglobulin kappa light chain isoform X39

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    47. XM_028832090.1 → XP_028687923.1  immunoglobulin kappa light chain isoform X43

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    48. XM_028832088.1 → XP_028687921.1  immunoglobulin kappa light chain isoform X41

      Conserved Domains (2) summary
      cd04980
      Location:24 → 128
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:134 → 233
      IgC_L; Immunoglobulin Constant domain

    49. XM_028832092.1 → XP_028687925.1  immunoglobulin kappa light chain isoform X45

      Conserved Domains (2) summary
      cd04980
      Location:22 → 127
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:133 → 232
      IgC_L; Immunoglobulin Constant domain

    50. XM_028832091.1 → XP_028687924.1  immunoglobulin kappa light chain isoform X44

      Conserved Domains (2) summary
      cd04980
      Location:22 → 127
      IgV_L_kappa; Immunoglobulin (Ig) light chain, kappa type, variable (V) domain
      cd07699
      Location:133 → 232
      IgC_L; Immunoglobulin Constant domain
    Nucleotide Protein
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