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    ACO2 aconitase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707441, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ACO2provided by VGNC
    Official Full Name
    aconitase 2provided by VGNC
    Primary source
    VGNC:VGNC:69379
    See related
    Ensembl:ENSMMUG00000001454
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ACO2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (9981538..10039834, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (83545554..83606531)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene X-ray repair cross complementing 6 Neighboring gene phosphomannomutase 1 Neighboring gene uncharacterized LOC114670348 Neighboring gene cold shock domain containing C2 Neighboring gene RNA polymerase III subunit H Neighboring gene uncharacterized LOC114670349 Neighboring gene PHD finger protein 5A Neighboring gene transducer of ERBB2, 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables aconitate hydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in tricarboxylic acid cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    aconitate hydratase, mitochondrial
    Names
    aconitase 2, mitochondrial
    NP_001248093.1
    XP_015005884.1
    XP_028683137.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261164.2 → NP_001248093.1  aconitate hydratase, mitochondrial

      See identical proteins and their annotated locations for NP_001248093.1

      Status: PROVISIONAL

      Source sequence(s)
      JV047194
      UniProtKB/TrEMBL
      A0A1D5QB91, F7BKH7
      Related
      ENSMMUP00000001942.2, ENSMMUT00000002057.4
      Conserved Domains (3) summary
      cd01584
      Location:95 → 505
      AcnA_Mitochondrial; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle
      cd01578
      Location:587 → 735
      AcnA_Mitochon_Swivel; Mitochondrial aconitase A swivel domain. Aconitase (also known as aconitate hydratase and citrate hydro-lyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes ...
      TIGR01340
      Location:45 → 775
      aconitase_mito; aconitate hydratase, mitochondrial

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      9981538..10039834 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015150398.2 → XP_015005884.1  aconitate hydratase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A1D5QB91, A0A5F8AU65
      Related
      ENSMMUP00000080481.1, ENSMMUT00000105367.1
      Conserved Domains (1) summary
      TIGR01340
      Location:45 → 744
      aconitase_mito; aconitate hydratase, mitochondrial

    2. XM_028827304.1 → XP_028683137.1  aconitate hydratase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A1D5QB91, A0A5F8AR81
      Related
      ENSMMUP00000080455.1, ENSMMUT00000105683.1
      Conserved Domains (1) summary
      TIGR01340
      Location:12 → 742
      aconitase_mito; aconitate hydratase, mitochondrial

    RNA

    1. XR_001447795.2 RNA Sequence

      Related
      ENSMMUT00000074749.2
    Nucleotide Protein
    Heading Accession and Version

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